Steroids

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ; Homo sapiens







111 Article(s)
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51 12798356 Molecular cloning and characterization of 3beta-hydroxysteroid dehydrogenase/Delta5-Delta4 isomerase cDNAs from Japanese eel ovary. 2003 May 1
52 12858014 Expression of 3beta-hydroxysteroid dehydrogenase and P450 side chain cleavage enzyme in the human uterine endometrium. 2003 Jun 30 1
53 14665668 Proplatelet formation of megakaryocytes is triggered by autocrine-synthesized estradiol. 2003 Dec 1 2
54 14672737 Characterization and modulation of sex steroid metabolizing activity in normal human keratinocytes in primary culture and HaCaT cells. 2003 Nov 1
55 12428206 Congenital adrenal hyperplasia due to 3beta-hydroxysteroid dehydrogenase/Delta(5)-Delta(4) isomerase deficiency. 2002 Aug 2
56 12429139 Glucocorticoids enhance activation of the human type II 3beta-hydroxysteroid dehydrogenase/Delta5-Delta4 isomerase gene. 2002 Sep 2
57 12530651 Differences in substrate and inhibitor kinetics of human type 1 and type 2 3beta-hydroxysteroid dehydrogenase are explained by the type 1 mutant, H156Y. 2002 Nov 1
58 11174850 Immunoelectron microscopic localization of 3beta-hydroxysteroid dehydrogenase and type 5 17beta-hydroxysteroid dehydrogenase in the human prostate and mammary gland. 2001 Feb 2
59 11344940 Congenital adrenal hyperplasia owing to 3 beta-hydroxysteroid dehydrogenase deficiency. 2001 Mar 1
60 11384880 Multiple signal transduction pathways mediate interleukin-4-induced 3beta-hydroxysteroid dehydrogenase/Delta5-Delta4 isomerase in normal and tumoral target tissues. 2001 Jan-Mar 2
61 11683717 cDNA cloning and physical mapping of porcine 3 beta-hydroxysteroid dehydrogenase/Delta 5-Delta 4 isomerase. 2001 Oct 1
62 11739460 3 beta hydroxysteroid dehydrogenase autoantibodies in patients with idiopathic premature ovarian failure target N- and C-terminal epitopes. 2001 Dec 1
63 10611255 Hormonal regulation of steroidogenic enzyme expression in granulosa cells during the peri-ovulatory interval in monkeys. 2000 Jan 1
64 10674396 Multiple signaling pathways mediate interleukin-4-induced 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase type 1 gene expression in human breast cancer cells. 2000 Feb 1
65 11155097 Developmental changes in steroidogenic enzymes in human postnatal adrenal cortex: immunohistochemical studies. 2000 Dec 1
66 9892013 Induction of 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase type 1 gene transcription in human breast cancer cell lines and in normal mammary epithelial cells by interleukin-4 and interleukin-13. 1999 Jan 3
67 10499513 Induction of 3beta-hydroxysteroid dehydrogenase/isomerase type 1 expression by interleukin-4 in human normal prostate epithelial cells, immortalized keratinocytes, colon, and cervix cancer cell lines. 1999 Oct 3
68 9617077 [The mechanisms of corticoids biosynthesis revealed by immunohistochemistry and in situ hybridization]. 1998 Apr 1
69 9768686 Adrenarche results from development of a 3beta-hydroxysteroid dehydrogenase-deficient adrenal reticularis. 1998 Oct 3
70 9029732 The regulation of 3 beta-hydroxysteroid dehydrogenase expression. 1997 Jan 1
71 9131995 NMR studies of the secondary structure in solution and the steroid binding site of delta5-3-ketosteroid isomerase in complexes with diamagnetic and paramagnetic steroids. 1997 Mar 25 3
72 9379114 Expression of the genes for 3 beta-hydroxysteroid dehydrogenase type 1 and cytochrome P450scc during syncytium formation by human placental cytotrophoblast cells in culture and the regulation by progesterone and estradiol. 1997 Sep 3
73 8943800 Regulation of 3 beta-hydroxysteroid dehydrogenase expression in human adrenocortical H295R cells. 1996 Sep 1
74 8954056 Identification of 3 beta-hydroxysteroid dehydrogenase as a novel target of steroid cell autoantibodies: association of autoantibodies with endocrine autoimmune disease. 1996 Dec 1
75 7588420 Immunohistochemical evaluation of the cellular localization and ontogeny of 3 beta-hydroxysteroid dehydrogenase/delta 5-4 isomerase in the human fetal adrenal gland. 1995 Feb-May 1
76 7626445 Molecular basis of human 3 beta-hydroxysteroid dehydrogenase deficiency. 1995 Jun 1
77 7835088 Genetic linkage mapping of HSD3B1 and HSD3B2 encoding human types I and II 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase close to D1S514 and the centromeric D1Z5 locus. 1995 1
78 8126127 Detection and functional characterization of the novel missense mutation Y254D in type II 3 beta-hydroxysteroid dehydrogenase (3 beta HSD) gene of a female patient with nonsalt-losing 3 beta HSD deficiency. 1994 Mar 1
79 8360152 Affinity radiolabeling identifies peptides and amino acids associated with substrate binding in human placental 3 beta-hydroxy-delta(5)-steroid dehydrogenase. 1993 Sep 5 1
80 8387158 Regulation of 3 beta-hydroxysteroid dehydrogenase and 17 beta-hydroxysteroid dehydrogenase messenger ribonucleic acid levels by cyclic adenosine 3',5'-monophosphate and phorbol myristate acetate in human choriocarcinoma cells. 1993 Mar 1
81 8444412 Formation of 7 alpha- and 7 beta-hydroxylated bile acid precursors from 27-hydroxycholesterol in human liver microsomes and mitochondria. 1993 Mar 1
82 8477648 Enzyme characteristics of two distinct forms of mouse 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase complementary deoxyribonucleic acids expressed in COS-1 cells. 1993 May 1
83 8486361 The genes encoding gonadal and nongonadal forms of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase are closely linked on mouse chromosome 3. 1993 Apr 1
84 8518207 3 beta-hydroxysteroid dehydrogenase activity in tissues of the human fetus determined with 5 alpha-androstane-3 beta,17 beta-diol and dehydroepiandrosterone as substrates. 1993 Jun 1
85 1381375 Immunohistochemical localization of 3 beta-hydroxy-5-ene-steroid dehydrogenase/delta 5----delta 4 isomerase in human placenta and fetal membranes throughout gestation. 1992 Sep 2
86 1390295 Ontogeny and subcellular localization of 3 beta-hydroxysteroid dehydrogenase (3 beta-HSD) in the human and rat adrenal, ovary and testis. 1992 Oct 1
87 1401999 Characterization, expression, and immunohistochemical localization of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase in human skin. 1992 Oct 1
88 1525044 Influence of 19-nortestosterone and androgens on progesterone biosynthetic enzymes in early human placental explants. 1992 Sep 1
89 1562516 Structure and tissue-specific expression of 3 beta-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase genes in human and rat classical and peripheral steroidogenic tissues. 1992 Mar 1
90 1569177 Immunocytochemical localization of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase in human ovary. 1992 May 2
91 1582424 Steroid hormone synthesis by a vaccinia enzyme: a new type of virus virulence factor. 1992 May 1
92 1831194 Characterization of the structure-activity relationships of rat types I and II 3 beta-hydroxysteroid dehydrogenase/delta 5 -delta 4 isomerase by site-directed mutagenesis and expression in HeLa cells. 1991 Aug 15 1
93 1846095 Regulation of 3 beta-hydroxysteroid dehydrogenase/delta 5----4-isomerase expression by adrenocorticotropin in bovine adrenocortical cells. 1991 Jan 1
94 1917679 Ontogeny of 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4 isomerase (3 beta-HSD) in human testis as studied by immunocytochemistry. 1991 May-Jun 1
95 1944309 Structure and expression of a new complementary DNA encoding the almost exclusive 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase in human adrenals and gonads. 1991 Aug 1
96 2050270 Characterization of macaque 3 beta-hydroxy-5-ene steroid dehydrogenase/delta 5-delta 4 isomerase: structure and expression in steroidogenic and peripheral tissues in primate. 1991 Feb 1
97 1700972 Immunohistochemical study of 3 beta-hydroxysteroid dehydrogenase in sex cord-stromal tumors of the ovary. 1990 2
98 2243100 Characterization of human 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase gene and its expression in mammalian cells. 1990 Nov 25 1
99 2351102 Light microscopic immunocytochemical localization of 3 beta-hydroxy-5-ene-steroid dehydrogenase/delta 5-delta 4-isomerase in the gonads and adrenal glands of the guinea pig. 1990 Jun 1
100 32138438 Immunolocalization of 3β-hydroxysteroid dehydrogenase in human adrenal cortex and in its disorders. 1990 Jun 1