Steroids

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ; Homo sapiens







111 Article(s)
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1 35087285 Association Between the Polymorphism of Steroid Hormone Metabolism Genes and High-Altitude Pulmonary Edema in the Chinese Han Population. 2022 1
2 34521750 Interleukins 4 and 13 drive lipid abnormalities in skin cells through regulation of sex steroid hormone synthesis. 2021 Sep 21 2
3 34890031 Steroid-converting enzymes in human adipose tissues and fat deposition with a focus on AKR1C enzymes. 2021 Dec 1
4 31936362 Establishment of A Reversibly Inducible Porcine Granulosa Cell Line. 2020 Jan 8 1
5 33290750 Expression of ARID1A in polycystic ovary syndrome and its effect on the proliferation and apoptosis of ovarian granulosa cells. 2020 Dec 1
6 31150682 Steroidogenic potential of human fetal kidney at early gestational age. 2019 Sep 1
7 29409762 Effects of antihistamines on the H295R steroidogenesis - Autocrine up-regulation following 3β-HSD inhibition. 2018 Apr 2
8 29939161 HSD3B1(1245A>C) variant regulates dueling abiraterone metabolite effects in prostate cancer. 2018 Aug 1 3
9 28655875 Proximal GATA-binding sites are essential for human HSD3B1 gene transcription in the placenta. 2017 Jun 27 2
10 28863887 Development of monoclonal antibodies against the human 3β-hydroxysteroid dehydrogenase/isomerase isozymes. 2017 Nov 1
11 26781511 High-Throughput Screening of Chemical Effects on Steroidogenesis Using H295R Human Adrenocortical Carcinoma Cells. 2016 Apr 1
12 27139182 Human 3β-hydroxysteroid dehydrogenase type 1 in human breast cancer: clinical significance and prognostic associations. 2016 Jul 1
13 27683264 Apelin (APLN) and Apelin Receptor (APLNR) in Human Ovary: Expression, Signaling, and Regulation of Steroidogenesis in Primary Human Luteinized Granulosa Cells. 2016 Nov 1
14 24832628 3βHSD and CYB5A double positive adrenocortical cells during adrenal development/aging. 2015 2
15 25947291 Contribution of a low-barrier hydrogen bond to catalysis is not significant in ketosteroid isomerase. 2015 May 1
16 25970467 Retinoic acid receptor beta and angiopoietin-like protein 1 are involved in the regulation of human androgen biosynthesis. 2015 May 13 1
17 23807211 Antitumoral effects of 9-cis retinoic acid in adrenocortical cancer. 2014 Mar 1
18 24075909 Immunolocalization of murine type VI 3β-hydroxysteroid dehydrogenase in the adrenal gland, testis, skin, and placenta. 2014 Jan 25 1
19 24292869 Possible role of the aromatase-independent steroid metabolism pathways in hormone responsive primary breast cancers. 2014 Jan 1
20 24372086 Two novel HSD3B2 missense mutations with diverse residual enzymatic activities for Δ5-steroids. 2014 Jun 2
21 25092869 Angiotensin II triggers expression of the adrenal gland zona glomerulosa-specific 3β-hydroxysteroid dehydrogenase isoenzyme through de novo protein synthesis of the orphan nuclear receptors NGFIB and NURR1. 2014 Oct 1
22 25416481 Using SILAC proteomics to investigate the effect of the mycotoxin, alternariol, in the human H295R steroidogenesis model. 2014 Dec 2
23 23318910 HSD3B1 is a specific trophoblast-associated marker not expressed in a wide spectrum of tumors. 2013 Feb 1
24 23913445 Rapid impact of progesterone on the neuronal growth cone. 2013 Oct 2
25 23928325 Neuroprotective action of synthetic steroids with oxygen bridge. Activity on GABAA receptor. 2013 Nov 2
26 24002028 Regulation of 3β-hydroxysteroid dehydrogenase/Δ⁵-Δ⁴ isomerase: a review. 2013 Sep 2 3
27 21631238 Genetic variation in the HSD3B1 gene and recurrent spontaneous abortions. 2012 Apr 1
28 21918127 Costs and consequences of cellular compartmentalization and substrate competition among human enzymes involved in androgen and estrogen synthesis. 2012 Jan 3
29 22024430 Variation in 3β-hydroxysteroid dehydrogenase activity and in pregnenolone supply rate can paradoxically alter androstenedione synthesis. 2012 Jan 4
30 22673022 Left ventricular structure and function in relation to steroid biosynthesis genes in a white population. 2012 Sep 1
31 23012064 Preparation of high-performance water-soluble quantum dots for biorecognition through fluorescence resonance energy transfer. 2012 Dec 1
32 23110082 Genetic susceptibility factors on genes involved in the steroid hormone biosynthesis pathway and progesterone receptor for gastric cancer risk. 2012 1
33 21949360 Direct measurement of the protein response to an electrostatic perturbation that mimics the catalytic cycle in ketosteroid isomerase. 2011 Oct 4 1
34 20420909 The functions of key residues in the inhibitor, substrate and cofactor sites of human 3beta-hydroxysteroid dehydrogenase type 1 are validated by mutagenesis. 2010 Jun 2
35 20660004 Association of HSD3B1 and HSD3B2 gene polymorphisms with essential hypertension, aldosterone level, and left ventricular structure. 2010 Oct 1
36 19117688 The 3beta-hydroxysteroid dehydrogenase inhibitor trilostane shows antidepressant properties in mice. 2009 Jun 1
37 18223326 HSD3B1 as a novel trophoblast-associated marker that assists in the differential diagnosis of trophoblastic tumors and tumorlike lesions. 2008 Feb 1
38 18426392 Targeting human glutathione transferase A3-3 attenuates progesterone production in human steroidogenic cells. 2008 Aug 15 3
39 18524572 Structure/function of the inhibition of human 3beta-hydroxysteroid dehydrogenase type 1 and type 2 by trilostane. 2008 Jul 2
40 17624763 Structure/function of human type 1 3beta-hydroxysteroid dehydrogenase: An intrasubunit disulfide bond in the Rossmann-fold domain and a Cys residue in the active site are critical for substrate and coenzyme utilization. 2007 Oct 2
41 17689071 Human 3beta-hydroxysteroid dehydrogenase types 1 and 2: Gene sequence variation and functional genomics. 2007 Oct 2
42 17975261 Steroidogenic factor 1/adrenal 4 binding protein transforms human bone marrow mesenchymal cells into steroidogenic cells. 2007 Nov 1
43 16009527 Immunolocalization of 3beta-hydroxysteroid dehydrogenase in normal and hyperplastic ram prostates. 2006 Jan 3
44 17056005 Characterization of the Rana grylio virus 3beta-hydroxysteroid dehydrogenase and its novel role in suppressing virus-induced cytopathic effect. 2006 Dec 8 2
45 15632317 Molecular biology of the 3beta-hydroxysteroid dehydrogenase/delta5-delta4 isomerase gene family. 2005 Jun 2
46 14672942 Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action. 2004 Mar 12 1
47 15131259 Transcription enhancer factor-5 and a GATA-like protein determine placental-specific expression of the Type I human 3beta-hydroxysteroid dehydrogenase gene, HSD3B1. 2004 Aug 2
48 15243798 Immunohistochemical localisation of 3beta-hydroxysteroid dehydrogenase in Sarcocystis spp. 2004 Aug 1
49 15291757 Serine 124 completes the Tyr, Lys and Ser triad responsible for the catalysis of human type 1 3beta-hydroxysteroid dehydrogenase. 2004 Aug 4
50 12756265 Steroid hormone synthesis by vaccinia virus suppresses the inflammatory response to infection. 2003 May 19 3