Pyruvic Acid

solute carrier family 16 member 1 ; Homo sapiens







39 Article(s)
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1 33559958 Monocarboxylate transporter 1 promotes proliferation and invasion of renal cancer cells by mediating acetate transport. 2021 Jun 2
2 34022218 Excess exogenous pyruvate inhibits lactate dehydrogenase activity in live cells in an MCT1-dependent manner. 2021 Jul 6
3 34254872 Solute carrier transporter superfamily member SLC16A1 is a potential prognostic biomarker and associated with immune infiltration in skin cutaneous melanoma. 2021 Dec 1
4 34625424 Hyperpolarized Carbon-13 MRI for Early Response Assessment of Neoadjuvant Chemotherapy in Breast Cancer Patients. 2021 Dec 1 2
5 34649623 3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation. 2021 Oct 14 1
6 32123312 Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition. 2020 Apr 1
7 32144120 Monocarboxylate Transporters (SLC16): Function, Regulation, and Role in Health and Disease. 2020 Apr 1
8 32450839 Pyruvate anaplerosis is a mechanism of resistance to pharmacological glutaminase inhibition in triple-receptor negative breast cancer. 2020 May 25 1
9 32839325 Hyperpolarized [1-13C]pyruvate-to-[1-13C]lactate conversion is rate-limited by monocarboxylate transporter-1 in the plasma membrane. 2020 Sep 8 3
10 31380330 A SLC16A1 Mutation in an Infant With Ketoacidosis and Neuroimaging Assessment: Expanding the Clinical Spectrum of MCT1 Deficiency. 2019 4
11 30177396 Genetic variations in the monocarboxylate transporter genes (SLC16A1, SLC16A3, and SLC16A11) in the Japanese population. 2018 Oct 1
12 30416849 An overview of MCT1 and MCT4 in GBM: small molecule transporters with large implications. 2018 1
13 28421181 MCT1 in Invasive Ductal Carcinoma: Monocarboxylate Metabolism and Aggressive Breast Cancer. 2017 2
14 29066459 Branched-chain ketoacids secreted by glioblastoma cells via MCT1 modulate macrophage phenotype. 2017 Dec 2
15 26876179 MCT1 Modulates Cancer Cell Pyruvate Export and Growth of Tumors that Co-express MCT1 and MCT4. 2016 Feb 23 5
16 27729975 Lactate/pyruvate transporter MCT-1 is a direct Wnt target that confers sensitivity to 3-bromopyruvate in colon cancer. 2016 1
17 24485392 MCT1 A1470T: a novel polymorphism for sprint performance? 2015 Jan 1
18 25403912 Genetic disruption of lactate/H+ symporters (MCTs) and their subunit CD147/BASIGIN sensitizes glycolytic tumor cells to phenformin. 2015 Jan 1 1
19 26528183 Lactate does not activate NF-κB in oxidative tumor cells. 2015 1
20 24486553 S-Nitrosation of monocarboxylate transporter 1: inhibition of pyruvate-fueled respiration and proliferation of breast cancer cells. 2014 Apr 1
21 22945392 Treatment with the MEK inhibitor U0126 induces decreased hyperpolarized pyruvate to lactate conversion in breast, but not prostate, cancer cells. 2013 Mar 1
22 23506875 The SLC16 gene family - structure, role and regulation in health and disease. 2013 Apr-Jun 2
23 21856423 Altered expression of brain monocarboxylate transporter 1 in models of temporal lobe epilepsy. 2012 Jan 2
24 22240841 Genetic variations of the MCT4 (SLC16A3) gene in the Chinese and Indian populations of Singapore. 2012 2
25 22407107 Role of monocarboxylate transporters in human cancers: state of the art. 2012 Feb 1
26 21081165 Monocarboxylate transporter 1 is deficient on microvessels in the human epileptogenic hippocampus. 2011 Feb 2
27 19826085 Kinetics of hyperpolarized 13C1-pyruvate transport and metabolism in living human breast cancer cells. 2009 Oct 27 4
28 19881260 Genetic variations in the MCT1 (SLC16A1) gene in the Chinese population of Singapore. 2009 4
29 18668440 The SLC16 monocaboxylate transporter family. 2008 Jul 2
30 17182800 Monocarboxylate transporter 1 mediates DL-2-Hydroxy-(4-methylthio)butanoic acid transport across the apical membrane of Caco-2 cell monolayers. 2007 Jan 1
31 17606506 Expression of monocarboxylate transporter 1 in oral and ocular canine melanocytic tumors. 2007 Jul 2
32 17701893 Physical exercise-induced hypoglycemia caused by failed silencing of monocarboxylate transporter 1 in pancreatic beta cells. 2007 Sep 2
33 16604139 Distribution of monocarboxylate transporters MCT1-MCT8 in rat tissues and human skeletal muscle. 2006 Feb 1
34 16326938 Lactate--a signal coordinating cell and systemic function. 2005 Dec 1
35 12739169 The SLC16 gene family-from monocarboxylate transporters (MCTs) to aromatic amino acid transporters and beyond. 2004 Feb 1
36 11943706 The precrystalline cytoplasmic granules of alveolar soft part sarcoma contain monocarboxylate transporter 1 and CD147. 2002 Apr 1
37 10471310 Helix 8 and helix 10 are involved in substrate recognition in the rat monocarboxylate transporter MCT1. 1999 Aug 31 1
38 10510291 The proton-linked monocarboxylate transporter (MCT) family: structure, function and regulation. 1999 Oct 15 1
39 9447934 Functional evidence for a monocarboxylate transporter (MCT) in strial marginal cells and molecular evidence for MCT1 and MCT2 in stria vascularis. 1997 Dec 1