Lactic Acid

solute carrier family 16 member 1 ; Homo sapiens







249 Article(s)
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1 34472101 l-lactic acidosis confers insensitivity to PKC inhibitors by competing for uptake via monocarboxylate transporters. 2022 Jan 2
2 34586586 Neuropeptide α-Melanocyte-Stimulating Hormone Promotes Neurological Recovery and Repairs Cerebral Ischemia/Reperfusion Injury in Type 1 Diabetes. 2022 Feb 1
3 34606041 Lactate shuttle: from substance exchange to regulatory mechanism. 2022 Jan 2
4 34619707 Coexpression of MCT1 and MCT4 in ALK-positive Anaplastic Large Cell Lymphoma: Diagnostic and Therapeutic Implications. 2022 Feb 1 1
5 34843897 Lactate Supply from Astrocytes to Neurons and its Role in Ischemic Stroke-induced Neurodegeneration. 2022 Jan 15 3
6 35054026 BSG (CD147) Serum Level and Genetic Variants Are Associated with Overall Survival in Acute Myeloid Leukaemia. 2022 Jan 10 1
7 35054513 Lactic Acid Permeability of Aquaporin-9 Enables Cytoplasmic Lactate Accumulation via an Ion Trap. 2022 Jan 14 2
8 35102189 Effect of endurance training and PGC-1α overexpression on calculated lactate production volume during exercise based on blood lactate concentration. 2022 Jan 31 1
9 35173374 Genetic characteristics of competitive swimmers: a review. 2022 Jan 1
10 35188217 Monocarboxylate transporter 1-mediated lactate accumulation promotes nucleus pulposus degeneration under hypoxia in a 3D multilayered nucleus pulposus degeneration model. 2022 Feb 21 2
11 35239073 Immunohistochemical evaluation and prognostic value of monocarboxylate transporter 1 (MCT1) and 4 (MCT4) in T-cell non-Hodgkin lymphoma. 2022 Mar 3 2
12 35406740 A Heme-Binding Transcription Factor BACH1 Regulates Lactate Catabolism Suggesting a Combined Therapy for Triple-Negative Breast Cancer. 2022 Mar 31 4
13 35440568 Inhibition of the succinyl dehydrogenase complex in acute myeloid leukemia leads to a lactate-fuelled respiratory metabolic vulnerability. 2022 Apr 19 2
14 35547368 Monocarboxylate Transporter 1 May Benefit Cerebral Ischemia via Facilitating Lactate Transport From Glial Cells to Neurons. 2022 7
15 35574309 Lactate Induces the Expressions of MCT1 and HCAR1 to Promote Tumor Growth and Progression in Glioblastoma. 2022 2
16 33221062 Synthesis and anticancer activity of new coumarin-3-carboxylic acid derivatives as potential lactatetransportinhibitors. 2021 Jan 1 4
17 33333023 Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates. 2021 Jan 21 2
18 33401672 The Harmonious Interplay of Amino Acid and Monocarboxylate Transporters Induces the Robustness of Cancer Cells. 2021 Jan 2 1
19 33450176 Recent developments of human monocarboxylate transporter (hMCT) inhibitors as anticancer agents. 2021 Mar 1
20 33486968 Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes. 2021 Mar 19 2
21 33548088 Compartmentalised metabolic programmes in human anagen hair follicles: New targets to modulate epithelial stem cell behaviour, keratinocyte proliferation and hair follicle immune status? 2021 May 1
22 33559958 Monocarboxylate transporter 1 promotes proliferation and invasion of renal cancer cells by mediating acetate transport. 2021 Jun 2
23 33645520 [Features of the in vitro expression profile of hippocampal neurogenic niche cells during optogenetic stimulation]. 2021 Jan 1
24 33933680 TMEM67, TMEM237, and Embigin in Complex With Monocarboxylate Transporter MCT1 Are Unique Components of the Photoreceptor Outer Segment Plasma Membrane. 2021 1
25 34020698 Lactate oxidative phosphorylation by annulus fibrosus cells: evidence for lactate-dependent metabolic symbiosis in intervertebral discs. 2021 May 21 3
26 34254872 Solute carrier transporter superfamily member SLC16A1 is a potential prognostic biomarker and associated with immune infiltration in skin cutaneous melanoma. 2021 Dec 1
27 34298681 MCT1 Is a New Prognostic Biomarker and Its Therapeutic Inhibition Boosts Response to Temozolomide in Human Glioblastoma. 2021 Jul 11 1
28 34471053 Pharmacological Inhibition of MCT4 Reduces 4-Hydroxytamoxifen Sensitivity by Increasing HIF-1α Protein Expression in ER-Positive MCF-7 Breast Cancer Cells. 2021 1
29 34475628 The MCT1 gene Glu490Asp polymorphism (rs1049434) is associated with endurance athlete status, lower blood lactate accumulation and higher maximum oxygen uptake. 2021 Sep 1
30 34625424 Hyperpolarized Carbon-13 MRI for Early Response Assessment of Neoadjuvant Chemotherapy in Breast Cancer Patients. 2021 Dec 1 1
31 34649623 3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation. 2021 Oct 14 3
32 34773210 Metabolic Transporters in the Peripheral Nerve-What, Where, and Why? 2021 Oct 1
33 29852858 Modulation of Immuno-biome during Radio-sensitization of Tumors by Glycolytic Inhibitors. 2020 1
34 31395464 Monocarboxylate transporters in cancer. 2020 Mar 1
35 31564440 Hyperpolarized MRI of Human Prostate Cancer Reveals Increased Lactate with Tumor Grade Driven by Monocarboxylate Transporter 1. 2020 Jan 7 1
36 31678436 The circadian clock regulates RPE-mediated lactate transport via SLC16A1 (MCT1). 2020 Jan 4
37 31853067 Metabolic heterogeneity confers differences in melanoma metastatic potential. 2020 Jan 1
38 31900520 Effect of transforming growth factor-β1 on functional expression of monocarboxylate transporter 1 in alveolar epithelial A549 cells. 2020 May 3
39 31936895 Inhibition of Alternative Cancer Cell Metabolism of EGFR Mutated Non-Small Cell Lung Cancer Serves as a Potential Therapeutic Strategy. 2020 Jan 10 2
40 31945319 Lactic acid promotes macrophage polarization through MCT-HIF1α signaling in gastric cancer. 2020 Mar 15 2
41 31964840 Imaging breast cancer using hyperpolarized carbon-13 MRI. 2020 Jan 28 2
42 32037723 GATA6 enhances the stemness of human colon cancer cells by creating a metabolic symbiosis through upregulating LRH-1 expression. 2020 Jun 1
43 32111097 Monocarboxylate Transporter 1 (MCT1) in Liver Pathology. 2020 Feb 26 1
44 32123312 Targeting metabolic activity in high-risk neuroblastoma through Monocarboxylate Transporter 1 (MCT1) inhibition. 2020 Apr 2
45 32138176 Impact of the Monocarboxylate Transporter-1 (MCT1)-Mediated Cellular Import of Lactate on Stemness Properties of Human Pancreatic Adenocarcinoma Cells †. 2020 Mar 3 12
46 32163224 Lowering the increased intracellular pH of human-induced pluripotent stem cell-derived endothelial cells induces formation of mature Weibel-Palade bodies. 2020 Jul 1
47 32257942 Lactate Beyond a Waste Metabolite: Metabolic Affairs and Signaling in Malignancy. 2020 4
48 32492393 Endothelial Lactate Controls Muscle Regeneration from Ischemia by Inducing M2-like Macrophage Polarization. 2020 Jun 2 1
49 32633891 Positive feedback in Cav-1-ROS signalling in PSCs mediates metabolic coupling between PSCs and tumour cells. 2020 Aug 1
50 32637597 Label-free sensing of exosomal MCT1 and CD147 for tracking metabolic reprogramming and malignant progression in glioma. 2020 Jun 2