Glutathione

glutathione S-transferase pi 1 ; Homo sapiens







180 Article(s)
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151 11113459 Location of the epoxide function determines specificity of the allelic variants of human glutathione transferase Pi toward benzo[c]chrysene diol epoxide isomers. 2000 Dec 8 3
152 9882456 Quantitative differences in the active-site hydrophobicity of five human glutathione S-transferase isoenzymes: water-soluble carcinogen-selective properties of the neoplastic GSTP1-1 species. 1999 Jan 15 2
153 9973324 Identification of 'tissue' transglutaminase binding proteins in neural cells committed to apoptosis. 1999 Feb 1
154 10334868 Differential catalytic efficiency of allelic variants of human glutathione S-transferase Pi in catalyzing the glutathione conjugation of thiotepa. 1999 Jun 1 4
155 10350652 Cellular balance of glutathione levels through the expression of gamma-glutamylcysteine synthetase and glutathione thiol transferase genes in human hepatic cells resistant to a glutathione poison. 1999 May 24 2
156 10353259 Interactions of prostaglandin A2 with the glutathione-mediated biotransformation system. 1999 Jun 15 2
157 10383436 Temperature adaptation of glutathione S-transferase P1-1. A case for homotropic regulation of substrate binding. 1999 Jul 2 7
158 10441116 Structure and function of residue 104 and water molecules in the xenobiotic substrate-binding site in human glutathione S-transferase P1-1. 1999 Aug 10 1
159 9525277 Differences in the catalytic efficiencies of allelic variants of glutathione transferase P1-1 towards carcinogenic diol epoxides of polycyclic aromatic hydrocarbons. 1998 Mar 2
160 9568063 Glutathione and glutathione S-transferases in human squamous cell carcinomas of the larynx and GSTM1 dependent risk. 1998 Jan-Feb 1
161 9771942 Specificities of human glutathione S-transferase isozymes toward anti-diol epoxides of methylchrysenes. 1998 Sep 1
162 9776312 Combined expression of multidrug resistance protein (MRP) and glutathione S-transferase P1-1 (GSTP1-1) in MCF7 cells and high level resistance to the cytotoxicities of ethacrynic acid but not oxazaphosphorines or cisplatin. 1998 Oct 15 3
163 9788613 Glutathione-dependent biotransformation of the alkylating drug thiotepa and transport of its metabolite monoglutathionylthiotepa in human MCF-7 breast cancer cells. 1998 Oct 15 3
164 9850062 Catalytic efficiencies of allelic variants of human glutathione S-transferase P1-1 toward carcinogenic anti-diol epoxides of benzo[c]phenanthrene and benzo[g]chrysene. 1998 Dec 1 3
165 9877184 GSTP1-1 stereospecifically catalyzes glutathione conjugation of ethacrynic acid. 1998 Dec 11 1
166 9020891 Epitope mapping of a monoclonal antibody to human glutathione transferase P1-1 the binding of which is inhibited by glutathione. 1997 Jan 15 3
167 9084911 Stereoselective conjugation of prostaglandin A2 and prostaglandin J2 with glutathione, catalyzed by the human glutathione S-transferases A1-1, A2-2, M1a-1a, and P1-1. 1997 Mar 2
168 9092542 Molecular cloning, characterization, and expression in Escherichia coli of full-length cDNAs of three human glutathione S-transferase Pi gene variants. Evidence for differential catalytic activity of the encoded proteins. 1997 Apr 11 4
169 9199210 Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-ox y-7,8,9,10-tetrahydrobenzo(a)pyrene. 1997 Jun 18 7
170 9281308 Mechanism of differential catalytic efficiency of two polymorphic forms of human glutathione S-transferase P1-1 in the glutathione conjugation of carcinogenic diol epoxide of chrysene. 1997 Sep 1 6
171 7728969 The high non-enzymatic conjugation rates of some glutathione S-transferase (GST) substrates at high glutathione concentrations. 1995 Apr 1
172 7887912 Forward and reverse catalysis and product sequestration by human glutathione S-transferases in the reaction of GSH with dietary aralkyl isothiocyanates. 1995 Mar 1 1
173 8555414 Glutathione conjugation of the cytostatic drug ifosfamide and the role of human glutathione S-transferases. 1995 Oct-Nov 1
174 8108434 Detoxication of base propenals and other alpha, beta-unsaturated aldehyde products of radical reactions and lipid peroxidation by human glutathione transferases. 1994 Feb 15 1
175 8313381 Reversible conjugation of ethacrynic acid with glutathione and human glutathione S-transferase P1-1. 1994 Feb 15 6
176 8340390 Evidence against a relationship between fatty acid ethyl ester synthase and the Pi class glutathione S-transferase in humans. 1993 Jul 25 1
177 8343114 Unusual reactivity of Tyr-7 of GSH transferase P1-1. 1993 Jul 15 1
178 8343115 Chemical modification of GSH transferase P1-1 confirms the presence of Arg-13, Lys-44 and one carboxylate group in the GSH-binding domain of the active site. 1993 Jul 15 2
179 8352805 Identification of ionizable groups essential for the enzyme catalysis on glutathione S-transferase P. 1993 Aug 16 3
180 2310397 Specific inactivation of glutathione S-transferases in class Pi by SH-modifiers. 1990 Feb 28 1