Benzo(a)pyrene

glutathione S-transferase pi 1 ; Homo sapiens







12 Article(s)
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1 35193440 Alterations of DNA methylation and mRNA levels of CYP1A1, GSTP1, and GSTM1 in human bronchial epithelial cells induced by benzo[a]pyrene. 2022 Mar 2
2 22298307 Identification of candidate biomarkers for early detection of human lung squamous cell cancer by quantitative proteomics. 2012 Jun 1
3 20498004 Benzo[a]pyrene increases the Nrf2 content by downregulating the Keap1 message. 2010 Aug 1
4 19330882 Differential protection by human glutathione S-transferase P1 against cytotoxicity of benzo[a]pyrene, dibenzo[a,l]pyrene, or their dihydrodiol metabolites, in bi-transgenic cell lines that co-express rat versus human cytochrome P4501A1. 2009 May 15 1
5 16885195 Expression of human glutathione S-transferase P1 confers resistance to benzo[a]pyrene or benzo[a]pyrene-7,8-dihydrodiol mutagenesis, macromolecular alkylation and formation of stable N2-Gua-BPDE adducts in stably transfected V79MZ cells co-expressing hCYP1A1. 2007 Jan 1
6 16933328 An association between glutathione S-transferase P1 gene polymorphism and younger age at onset of lung carcinoma. 2006 Oct 1 1
7 16099480 Coffee consumption induces GSTP in plasma and protects lymphocytes against (+/-)-anti-benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide induced DNA-damage: results of controlled human intervention trials. 2005 Dec 11 1
8 12660004 Association between glutathione S-transferase p1 polymorphisms and lung cancer risk in Caucasians: a case-control study. 2003 Apr 1
9 10344744 Differential protection against benzo[a]pyrene-7,8-dihydrodiol-9,10-epoxide-induced DNA damage in HepG2 cells stably transfected with allelic variants of pi class human glutathione S-transferase. 1999 May 15 1
10 9525277 Differences in the catalytic efficiencies of allelic variants of glutathione transferase P1-1 towards carcinogenic diol epoxides of polycyclic aromatic hydrocarbons. 1998 Mar 4
11 9855012 Detoxification of optically active bay- and fjord-region polycyclic aromatic hydrocarbon dihydrodiol epoxides by human glutathione transferase P1-1 expressed in Chinese hamster V79 cells. 1998 Nov 1
12 9199210 Active site architecture of polymorphic forms of human glutathione S-transferase P1-1 accounts for their enantioselectivity and disparate activity in the glutathione conjugation of 7beta,8alpha-dihydroxy-9alpha,10alpha-ox y-7,8,9,10-tetrahydrobenzo(a)pyrene. 1997 Jun 18 1