Diphosphonates

geranylgeranyl diphosphate synthase 1 ; Homo sapiens







15 Article(s)
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1 31427399 Metal Coordination Is Crucial for Geranylgeranyl Diphosphate Synthase-Bisphosphonate Interactions: A Crystallographic and Computational Analysis. 2019 Nov 4
2 29276048 Specific Inhibition of the Bifunctional Farnesyl/Geranylgeranyl Diphosphate Synthase in Malaria Parasites via a New Small-Molecule Binding Site. 2018 Feb 15 4
3 30216851 Novel bisphosphonates with antiresorptive effect in bone mineralization and osteoclastogenesis. 2018 Oct 5 1
4 30275041 Reduced Activity of Geranylgeranyl Diphosphate Synthase Mutant Is Involved in Bisphosphonate-Induced Atypical Fractures. 2018 Dec 8
5 30283886 Genetic Risk Factors for Atypical Femoral Fractures (AFFs): A Systematic Review. 2018 Jan 1
6 27428767 Fluorescent Farnesyl Diphosphate Analogue: A Probe To Validate trans-Prenyltransferase Inhibitors. 2016 Aug 9 1
7 23610597 Chemo-Immunotherapeutic Anti-Malarials Targeting Isoprenoid Biosynthesis. 2013 Apr 11 1
8 23919676 Moiety-linkage map reveals selective nonbisphosphonate inhibitors of human geranylgeranyl diphosphate synthase. 2013 Sep 23 2
9 20191015 Genetic polymorphism of geranylgeranyl diphosphate synthase (GGSP1) predicts bone density response to bisphosphonate therapy in Korean women. 2010 Mar 2
10 19309137 Lipophilic bisphosphonates as dual farnesyl/geranylgeranyl diphosphate synthase inhibitors: an X-ray and NMR investigation. 2009 Apr 15 3
11 18800762 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates: a crystallographic and computational investigation. 2008 Sep 25 1
12 17208200 Digeranyl bisphosphonate inhibits geranylgeranyl pyrophosphate synthase. 2007 Feb 23 1
13 17535895 Bisphosphonates target multiple sites in both cis- and trans-prenyltransferases. 2007 Jun 12 3
14 13679234 A new bisphosphonate, YM529 induces apoptosis in HL60 cells by decreasing phosphorylation of single survival signal ERK. 2003 Oct 10 1
15 12014956 Inhibition of geranylgeranyl diphosphate synthase by bisphosphonates and diphosphates: a potential route to new bone antiresorption and antiparasitic agents. 2002 May 23 3