| 51 |
17459328 | Energetics of heterotropic cooperativity between alpha-naphthoflavone and testosterone binding to CYP3A4. | 2007 Jul 1 |
1 |
| 52 |
17548930 | [Hepatic CYP3A activity in association with development of osteonecrosis of the femoral head]. | 2007 Jun |
2 |
| 53 |
17636047 | Down-regulation of pregnane X receptor contributes to cell growth inhibition and apoptosis by anticancer agents in endometrial cancer cells. | 2007 Oct |
2 |
| 54 |
16344723 | Genetic signature consistent with selection against the CYP3A4*1B allele in non-African populations. | 2006 Jan |
1 |
| 55 |
16430309 | Significance of the minor cytochrome P450 3A isoforms. | 2006 |
1 |
| 56 |
16713641 | Up-regulation of the alligator CYP3A77 gene by toxaphene and dexamethasone and its short term effect on plasma testosterone concentrations. | 2006 Jun 30 |
6 |
| 57 |
17015057 | Low hepatic cytochrome P450 3A activity is a risk for corticosteroid-induced osteonecrosis. | 2006 Oct |
2 |
| 58 |
17526937 | Tamoxifen activates CYP3A4 and MDR1 genes through steroid and xenobiotic receptor in breast cancer cells. | 2006 Dec |
2 |
| 59 |
15331348 | Mechanism of rifampicin and pregnane X receptor inhibition of human cholesterol 7 alpha-hydroxylase gene transcription. | 2005 Jan |
4 |
| 60 |
15634031 | The influence of age and sex on the clearance of cytochrome P450 3A substrates. | 2005 |
6 |
| 61 |
15650019 | The pregnane X receptor regulates gene expression in a ligand- and promoter-selective fashion. | 2005 May |
6 |
| 62 |
15698577 | Regulation of CYP3A genes in the human respiratory tract. | 2005 Jan 15 |
1 |
| 63 |
15707415 | Consequences of genetic polymorphisms for sirolimus requirements after renal transplant in patients on primary sirolimus therapy. | 2005 Mar |
1 |
| 64 |
15832810 | Induction of phase I, II and III drug metabolism/transport by xenobiotics. | 2005 Mar |
1 |
| 65 |
15922010 | Constitutive and xenobiotics-induced expression of a novel CYP3A gene from zebrafish larva. | 2005 Jun 15 |
1 |
| 66 |
15955870 | CYP3A5 mRNA degradation by nonsense-mediated mRNA decay. | 2005 Sep |
1 |
| 67 |
16261523 | Effects of St John's wort (Hypericum perforatum L.) extract on plasma androgen concentrations in healthy men and women: a pilot study. | 2005 Oct |
2 |
| 68 |
14569421 | Cytochrome P450 3A and their regulation. | 2004 Jan |
1 |
| 69 |
14715379 | Within-person variability of urinary 6beta-hydroxycortisol to urinaryl ratios in Caucasian women. | 2004 Jan |
1 |
| 70 |
15060513 | Tacrolimus therapy according to mucosal MDR1 levels in small-bowel transplant recipients. | 2004 Apr |
1 |
| 71 |
15228164 | Genetics of the variable expression of CYP3A in humans. | 2004 Apr |
1 |
| 72 |
15350151 | Drug interactions with St John's wort : mechanisms and clinical implications. | 2004 |
1 |
| 73 |
15365655 | Effects of growth hormone deficiency and rhGH replacement therapy on the 6beta-hydroxycortisol/free cortisol ratio, a marker of CYP3A activity, in growth hormone-deficient children. | 2004 Oct |
1 |
| 74 |
15548381 | A PXR reporter gene assay in a stable cell culture system: CYP3A4 and CYP2B6 induction by pesticides. | 2004 Dec 15 |
1 |
| 75 |
12642469 | CYP3A4 and CYP3A7-mediated carbamazepine 10,11-epoxidation are activated by differential endogenous steroids. | 2003 Apr |
4 |
| 76 |
12842592 | Hepatic versus extrahepatic expression of CYP3A30 and CYP3A56 in adult killifish (Fundulus heteroclitus). | 2003 Aug 20 |
1 |
| 77 |
12970323 | Expression and potential roles of pregnane X receptor in endometrial cancer. | 2003 Sep |
3 |
| 78 |
14515059 | The CYP3A4*1B allele increases risk for small cell lung cancer: effect of gender and smoking dose. | 2003 Oct |
1 |
| 79 |
14624194 | Nefazodone inhibits methylprednisolone disposition and enhances its adrenal-suppressant effect. | 2003 Dec |
2 |
| 80 |
14690416 | Direct interaction between substrates and endogenous steroids in the active site may change the activity of cytochrome P450 3A4. | 2003 Dec 30 |
4 |
| 81 |
11871398 | Identification of the human P450 enzymes involved in the in vitro metabolism of the synthetic steroidal hormones Org 4060 and Org 30659. | 2002 Feb |
4 |
| 82 |
11875366 | Common allelic variants of cytochrome P4503A4 and their prevalence in different populations. | 2002 Mar |
1 |
| 83 |
11950784 | Effects of endogenous steroids on CYP3A4-mediated drug metabolism by human liver microsomes. | 2002 May |
3 |
| 84 |
12072427 | Putative role of the orphan nuclear receptor SXR (steroid and xenobiotic receptor) in the mechanism of CYP3A4 inhibition by xenobiotics. | 2002 Sep 6 |
2 |
| 85 |
12084857 | Pharmacokinetics of vincristine monotherapy in childhood acute lymphoblastic leukemia. | 2002 Jul |
1 |
| 86 |
12153551 | Growth hormone replacement therapy induces codeine clearance. | 2002 Jul |
1 |
| 87 |
12167569 | Glucocorticoid-mediated induction of CYP3A4 is decreased by disruption of a protein: DNA interaction distinct from the pregnane X receptor response element. | 2002 Sep |
1 |
| 88 |
12406645 | Genetic contribution to variable human CYP3A-mediated metabolism. | 2002 Nov 18 |
1 |
| 89 |
12433811 | Functional properties of a rainbow trout CYP3A27 expressed by recombinant baculovirus in insect cells. | 2002 Dec |
1 |
| 90 |
12451243 | Lowered blood concentration of tacrolimus and its recovery with changes in expression of CYP3A and P-glycoprotein after high-dose steroid therapy. | 2002 Nov 27 |
2 |
| 91 |
11248085 | The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity. | 2001 Mar 13 |
2 |
| 92 |
11279519 | Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression. | 2001 Apr |
1 |
| 93 |
11581012 | Bisphenol-A, an environmental estrogen, activates the human orphan nuclear receptor, steroid and xenobiotic receptor-mediated transcription. | 2001 Oct |
3 |
| 94 |
12690615 | CYP3A4: a potential prostate cancer risk factor for high-risk groups. | 2001 Jul-Aug |
1 |
| 95 |
10628745 | The pregnane X receptor: a promiscuous xenobiotic receptor that has diverged during evolution. | 2000 Jan |
2 |
| 96 |
10666307 | The importance of SRS-1 residues in catalytic specificity of human cytochrome P450 3A4. | 2000 Feb 15 |
1 |
| 97 |
10772626 | Regulation of the CYP3A4 gene by hydrocortisone and xenobiotics: role of the glucocorticoid and pregnane X receptors. | 2000 May |
1 |
| 98 |
10935643 | Humanized xenobiotic response in mice expressing nuclear receptor SXR. | 2000 Jul 27 |
1 |
| 99 |
11162923 | Quantitative structure-activity relationships in a series of endogenous and synthetic steroids exhibiting induction of CYP3A activity and hepatomegaly associated with increased DNA synthesis. | 2000 Nov 15 |
2 |
| 100 |
10037683 | The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene. | 1999 Mar 5 |
1 |