| 1 |
34137279 | Potential Dexamethasone-Direct Oral Anticoagulant Drug Interaction: Is This a Concern in COVID? | 2022 Mar |
4 |
| 2 |
34791318 | Dexamethasone is a dose-dependent perpetrator of drug-drug interactions: implications for use in people living with HIV. | 2022 Feb 23 |
3 |
| 3 |
35039908 | Evaluation of hepatic CYP3A enzyme activity using endogenous markers in lung cancer patients treated with cisplatin, dexamethasone, and aprepitant. | 2022 Apr |
3 |
| 4 |
35403851 | Clinical interaction between dexamethasone and aprepitant in chemotherapy for lymphoma. | 2022 Jun |
3 |
| 5 |
33495943 | Elevated levels of expression of cytochrome P450 3A4 in a human liver epithelial cell line in differentiation-inducing conditions. | 2021 May |
2 |
| 6 |
33773552 | Pharmacokinetics of Dexamethasone when Administered with Fosaprepitant for Chemotherapy-Induced Nausea and Vomiting and Differences in Dose-Dependent Antiemetic Effects. | 2021 Mar 1 |
1 |
| 7 |
34337735 | Should we be concerned when COVID-19-positive patients take opioids to control their pain? Insights from a pharmacological point of view. | 2021 Jul |
1 |
| 8 |
34627953 | The detoxification effect of cytochrome P450 3A4 on gelsemine-induced toxicity. | 2021 Dec 15 |
1 |
| 9 |
32240873 | Dexamethasone simulates the anticancer effect of nano-formulated paclitaxel in breast cancer cells. | 2020 Jun |
1 |
| 10 |
30919109 | Mechanisms of CYP3A Induction During Pregnancy: Studies in HepaRG Cells. | 2019 Mar 27 |
1 |
| 11 |
31127319 | Clinical implications of an analysis of pharmacokinetics of crizotinib coadministered with dexamethasone in patients with non-small cell lung cancer. | 2019 Jul |
1 |
| 12 |
31527544 | Assessing Drug Interaction and Pharmacokinetics of Loxoprofen in Mice Treated with CYP3A Modulators. | 2019 Sep 16 |
1 |
| 13 |
30072626 | Exploring the Metabolism of Loxoprofen in Liver Microsomes: The Role of Cytochrome P450 and UDP-Glucuronosyltransferase in Its Biotransformation. | 2018 Aug 2 |
1 |
| 14 |
27226420 | Clinical pharmacokinetics of panobinostat, a novel histone deacetylase (HDAC) inhibitor: review and perspectives. | 2017 Apr |
1 |
| 15 |
28194109 | Delayed Chemotherapy-Induced Nausea and Vomiting: Pathogenesis, Incidence, and Current Management. | 2017 |
1 |
| 16 |
26966071 | Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells. | 2016 Apr 15 |
1 |
| 17 |
25434721 | Overexpression of CYP3A5 attenuates inducibility and activity of CYP3A4 in HepG2 cells. | 2015 Apr |
1 |
| 18 |
25915157 | Human bone marrow niche chemoprotection mediated by cytochrome P450 enzymes. | 2015 Jun 20 |
2 |
| 19 |
26301745 | Transport and uptake of clausenamide enantiomers in CYP3A4-transfected Caco-2 cells: An insight into the efflux-metabolism alliance. | 2015 Nov 1 |
1 |
| 20 |
26330331 | Preclinical assessment of the interactions between the antiretroviral drugs, ritonavir and efavirenz, and the tyrosine kinase inhibitor erlotinib. | 2015 Oct |
1 |
| 21 |
24191259 | Studies on the role of metabolic activation in tyrosine kinase inhibitor-dependent hepatotoxicity: induction of CYP3A4 enhances the cytotoxicity of lapatinib in HepaRG cells. | 2014 Jan |
2 |
| 22 |
24492672 | Development of mice exhibiting hepatic microsomal activity of human CYP3A4 comparable to that in human liver microsomes by intravenous administration of an adenovirus vector expressing human CYP3A4. | 2014 |
2 |
| 23 |
24674673 | Cytochrome P450 genetic polymorphism in neonatal drug metabolism: role and practical consequences towards a new drug culture in neonatology. | 2014 Jan-Mar |
1 |
| 24 |
22253426 | Expression and regulation of human fetal-specific CYP3A7 in mice. | 2012 Mar |
1 |
| 25 |
22333269 | Lower expression of HNF4α and PGC1α might impair rifampicin-mediated CYP3A4 induction under conditions where PXR is overexpressed in human fetal liver cells. | 2012 |
4 |
| 26 |
22370628 | Effect of CYP3A4 inducer dexamethasone on hepatotoxicity of lapatinib: clinical and in vitro evidence. | 2012 Jun |
1 |
| 27 |
22673009 | Mechanisms of CYP3A induction by glucocorticoids in human fetal liver cells. | 2012 |
3 |
| 28 |
20798939 | NCT01110291: induction of CYP3A activity and lowered exposure to docetaxel in patients with primary breast cancer. | 2011 Jun |
1 |
| 29 |
21219911 | Andrographolide and 14-deoxy-11, 12-didehydroandrographolide inhibit cytochrome P450s in HepG2 hepatoma cells. | 2011 Feb 28 |
1 |
| 30 |
21436605 | Comparative study of culture conditions for maintaining CYP3A4 and ATP-binding cassette transporters activity in primary cultured human hepatocytes. | 2011 |
1 |
| 31 |
21952236 | Intrinsic sexually dimorphic expression of the principal human CYP3A4 correlated with suboptimal activation of GH/glucocorticoid-dependent transcriptional pathways in men. | 2011 Dec |
1 |
| 32 |
19022227 | Effects of dexamethasone, administered for growth promoting purposes, upon the hepatic cytochrome P450 3A expression in the veal calf. | 2009 Feb 1 |
6 |
| 33 |
19429418 | Comparison of effects of VDR versus PXR, FXR and GR ligands on the regulation of CYP3A isozymes in rat and human intestine and liver. | 2009 May 12 |
1 |
| 34 |
17826359 | Effects of mammalian CYP3A inducers on CYP3A-related enzyme activities in grass carp (Ctenopharyngodon idellus): Possible implications for the establishment of a fish CYP3A induction model. | 2008 Jan |
2 |
| 35 |
18037906 | Comparison of the induction profile for drug disposition proteins by typical nuclear receptor activators in human hepatic and intestinal cells. | 2008 Feb |
1 |
| 36 |
18094037 | Induction of metabolism and transport in human intestine: validation of precision-cut slices as a tool to study induction of drug metabolism in human intestine in vitro. | 2008 Mar |
1 |
| 37 |
18332045 | Phthalate induction of CYP3A4 is dependent on glucocorticoid regulation of PXR expression. | 2008 Jun |
4 |
| 38 |
18490434 | The influence of CYP3A5 genotype on dexamethasone induction of CYP3A activity in African Americans. | 2008 Aug |
2 |
| 39 |
17124593 | Dexamethasone as a probe for CYP3A4 metabolism: evidence of gender effect. | 2007 Jul |
1 |
| 40 |
17207564 | Cytotoxicity of chloroacetanilide herbicide alachlor in HepG2 cells independent of CYP3A4 and CYP3A7. | 2007 May |
1 |
| 41 |
17978482 | Comparison of basal gene expression and induction of CYP3As in HepG2 and human fetal liver cells. | 2007 Nov |
3 |
| 42 |
16160083 | Sexually dimorphic regulation of hepatic isoforms of human cytochrome p450 by growth hormone. | 2006 Jan |
2 |
| 43 |
16713641 | Up-regulation of the alligator CYP3A77 gene by toxaphene and dexamethasone and its short term effect on plasma testosterone concentrations. | 2006 Jun 30 |
2 |
| 44 |
15656694 | Interactions between antiretrovirals and antineoplastic drug therapy. | 2005 |
3 |
| 45 |
15832810 | Induction of phase I, II and III drug metabolism/transport by xenobiotics. | 2005 Mar |
1 |
| 46 |
15922010 | Constitutive and xenobiotics-induced expression of a novel CYP3A gene from zebrafish larva. | 2005 Jun 15 |
1 |
| 47 |
15963093 | Dexamethasone as a probe for vinorelbine clearance. | 2005 Jul |
1 |
| 48 |
15055869 | Aprepitant in antiemetic combinations to prevent chemotherapy-induced nausea and vomiting. | 2004 Feb |
1 |
| 49 |
15081938 | Simultaneous determination of dexamethasone and 6 beta-hydroxydexamethasone in urine using solid-phase extraction and liquid chromatography: applications to in vivo measurement of cytochrome P450 3A4 activity. | 2004 May 25 |
1 |
| 50 |
15120618 | Expression and induction of CYP3As in human fetal hepatocytes. | 2004 May 28 |
4 |