Ethanol

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







25 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 34842392 Plumbagin and Plumbago indica Differentially Modulated Cytochrome P450 and Transporter Profiles in BeWo and HepG2 Cells. 2021 Jan 2
2 30306496 Effect of 95% Ethanol Khat Extract and Cathinone on in vitro Human Recombinant Cytochrome P450 (CYP) 2C9, CYP2D6, and CYP3A4 Activity. 2019 Jun 1
3 30683357 Assessment of electrocatalytic hydroxylase activity of cytochrome P450 3A4 (CYP3A4) by means of derivatization of 6β-hydroxycortisol by sulfuric acid for fluorimetric assay. 2019 May 1 1
4 29633238 Drinking Ethanol Has Few Acute Effects on CYP2C9, CYP2C19, NAT2, and P-Glycoprotein Activities but Somewhat Inhibits CYP1A2, CYP2D6, and Intestinal CYP3A: So What? 2018 Dec 1
5 29848078 Influence of ethanol on the metabolism of alprazolam. 2018 Jun 5
6 30532626 Novel plant inducers of PXR-dependent cytochrome P450 3A4 expression in HepG2 cells. 2018 Dec 1
7 30607725 A New Method for Quantitative Determination of Steroid Metabolites of Cytochrome P450-Dependent Reactions Using Fluorescent Spectroscopy. 2018 Nov 1
8 28231276 Alterations in cellular pharmacokinetics and pharmacodynamics of elvitegravir in response to ethanol exposure in HIV-1 infected monocytic (U1) cells. 2017 1
9 28616684 Influence of Ethanol on Darunavir Hepatic Clearance and Intracellular PK/PD in HIV-Infected Monocytes, and CYP3A4-Darunavir Interactions Using Inhibition and in Silico Binding Studies. 2017 Sep 2
10 26727525 Chronic Effects of Ethanol and/or Darunavir/Ritonavir on U937 Monocytic Cells: Regulation of Cytochrome P450 and Antioxidant Enzymes, Oxidative Stress, and Cytotoxicity. 2016 Jan 2
11 26872388 Effect of Ethanol on the Metabolic Characteristics of HIV-1 Integrase Inhibitor Elvitegravir and Elvitegravir/Cobicistat with CYP3A: An Analysis Using a Newly Developed LC-MS/MS Method. 2016 8
12 25684704 Investigation of CYP3A4 and CYP2D6 Interactions of Withania somnifera and Centella asiatica in Human Liver Microsomes. 2015 May 1
13 24223062 Opposite Effects of Single-Dose and Multidose Administration of the Ethanol Extract of Danshen on CYP3A in Healthy Volunteers. 2013 2
14 21842479 Aloe vera juice: IC₅₀ and dual mechanistic inhibition of CYP3A4 and CYP2D6. 2012 Mar 1
15 21524698 Identification of novel pregnane X receptor activators from traditional Chinese medicines. 2011 Jun 14 3
16 21682753 Differential effects of ethanol on spectral binding and inhibition of cytochrome P450 3A4 with eight protease inhibitors antiretroviral drugs. 2011 Dec 7
17 20937259 Effect of ethanol on spectral binding, inhibition, and activity of CYP3A4 with an antiretroviral drug nelfinavir. 2010 Nov 5 6
18 17084997 Ethanol oxidation into acetaldehyde by 16 recombinant human cytochrome P450 isoforms: role of CYP2C isoforms in human liver microsomes. 2006 Dec 15 2
19 15285839 Ethanol inhibits in-vitro metabolism of nifedipine, triazolam and testosterone in human liver microsomes. 2004 Aug 5
20 15554233 The discovery of the microsomal ethanol oxidizing system and its physiologic and pathologic role. 2004 Oct 1
21 12824820 Induction of CYP3A by ethanol in multiple in vitro and in vivo models. 2003 Jun 13
22 11236840 Azide inhibits human cytochrome P -4502E1, 1A2, and 3A4. 2001 Feb 5
23 10397283 Microsomal ethanol-oxidizing system (MEOS): the first 30 years (1968-1998)--a review. 1999 Jun 1
24 9884161 Respective roles of human cytochrome P-4502E1, 1A2, and 3A4 in the hepatic microsomal ethanol oxidizing system. 1998 Dec 5
25 7574728 Ethanol and isopentanol increase CYP3A and CYP2E in primary cultures of human hepatocytes. 1995 Oct 1 7