Simvastatin

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







123 Article(s)
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#Total Relationships
101 14727985 Management of protease inhibitor-associated hyperlipidemia. 2002 1
102 11197581 Rhabdomyolysis secondary to a drug interaction between simvastatin and clarithromycin. 2001 Jan 2
103 11281188 Myositis, microvesicular hepatitis, and progression to cirrhosis from troglitazone added to simvastatin. 2001 Feb 1
104 11465417 Inhibition of in vitro metabolism of simvastatin by itraconazole in humans and prediction of in vivo drug-drug interactions. 2001 May 1
105 11475198 [Metabolic interactions with statins]. 2001 Jan 20 1
106 11497338 Study of the drug-drug interaction between simvastatin and cisapride in man. 2001 Jun 1
107 11550401 Simvastatin-diltiazem drug interaction resulting in rhabdomyolysis and hepatitis. 2001 Sep 2
108 11584328 Treatment of the elderly with 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors: focus on drug interactions. 2001 Jul 1
109 11753267 Different effects of St John's wort on the pharmacokinetics of simvastatin and pravastatin. 2001 Dec 4
110 10741630 The interaction of diltiazem with simvastatin. 2000 Mar 5
111 11005703 Comparative tolerability of the HMG-CoA reductase inhibitors. 2000 Sep 1
112 11029845 HMG-CoA reductase inhibitors: assessing differences in drug interactions and safety profiles. 2000 Sep-Oct 1
113 11075313 Simvastatin does not affect CYP3A activity, quantified by the erythromycin breath test and oral midazolam pharmacokinetics, in healthy male subjects. 2000 Nov 1
114 11126989 [Undesirable drug interactions of hypolipemic drugs]. 2000 Sep 1
115 11149552 Rhabdomyolysis and acute renal failure in a cardiac transplant recipient due to multiple drug interactions. 2000 Dec 1
116 11180018 Rifampin greatly reduces plasma simvastatin and simvastatin acid concentrations. 2000 Dec 4
117 33237691 Lipid and Lipoprotein Levels in Patients with COVID-19 Infections 2000 1
118 10215754 Metabolic interactions between mibefradil and HMG-CoA reductase inhibitors: an in vitro investigation with human liver preparations. 1999 Mar 1
119 10513779 Concomitant use of cytochrome P450 3A4 inhibitors and simvastatin. 1999 Oct 1 3
120 10665838 New insights into the pharmacodynamic and pharmacokinetic properties of statins. 1999 Dec 1
121 9542477 Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole. 1998 Mar 1
122 9728898 Erythromycin and verapamil considerably increase serum simvastatin and simvastatin acid concentrations. 1998 Aug 1
123 9321523 In vitro metabolism of simvastatin in humans [SBT]identification of metabolizing enzymes and effect of the drug on hepatic P450s. 1997 Oct 1