123 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
51 | 22451032 | Interleukin-6 and cytochrome-P450, reason for concern? | 2012 Sep | 1 |
52 | 22529023 | Statin medication in patients treated with antiepileptic drugs in Norway. | 2012 Aug | 1 |
53 | 22912565 | Literature based drug interaction prediction with clinical assessment using electronic medical records: novel myopathy associated drug interactions. | 2012 | 1 |
54 | 23032911 | Paracetamol and simvastatin: a potential interaction resulting in hepatotoxicity. | 2012 | 2 |
55 | 21443601 | Pharmacokinetic interactions between alitretinoin and ketoconazole or simvastatin or ciclosporin A. | 2011 Apr | 1 |
56 | 21844990 | Tacrolimus and 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors: An interaction study in CYP3A5 non-expressors, renal transplant recipients. | 2011 Jul | 1 |
57 | 21883349 | Drug interactions with mitotane by induction of CYP3A4 metabolism in the clinical management of adrenocortical carcinoma. | 2011 Nov | 1 |
58 | 21946898 | Novel CYP3A4 intron 6 single nucleotide polymorphism is associated with simvastatin-mediated cholesterol reduction in the Rotterdam Study. | 2011 Dec | 8 |
59 | 22287853 | Two-way pharmacokinetic interaction studies between saxagliptin and cytochrome P450 substrates or inhibitors: simvastatin, diltiazem extended-release, and ketoconazole. | 2011 | 1 |
60 | 19802823 | Influence of genetic variation in CYP3A4 and ABCB1 on dose decrease or switching during simvastatin and atorvastatin therapy. | 2010 Jan | 4 |
61 | 19943026 | [Interactions with antiretroviral drugs]. | 2010 Jan | 1 |
62 | 20150526 | Effects of concomitant therapy with diltiazem on the lipid responses to simvastatin in Chinese subjects. | 2010 Oct | 1 |
63 | 20203109 | Selection of alternative CYP3A4 probe substrates for clinical drug interaction studies using in vitro data and in vivo simulation. | 2010 Jun | 2 |
64 | 20829626 | Management of dyslipidemia in Cushing's syndrome. | 2010 | 2 |
65 | 21045169 | Rhabdomyolysis in a patient receiving high-dose simvastatin after the induction of therapeutic hypothermia. | 2010 Dec | 1 |
66 | 21105332 | [Effect of polymorphisms of cytochrome P450 and apolipoprotein E genes on therapeutic efficacy of statins]. | 2010 | 1 |
67 | 19206087 | Rhabdomyolysis reports show interaction between simvastatin and CYP3A4 inhibitors. | 2009 Apr | 2 |
68 | 19220274 | Co-medication of statins and CYP3A4 inhibitors before and after introduction of new reimbursement policy. | 2009 Feb | 3 |
69 | 19429419 | Effects of acid and lactone forms of 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors on the induction of MDR1 expression and function in LS180 cells. | 2009 May 12 | 1 |
70 | 20183988 | [Statins under fire: justified or not?]. | 2009 Dec | 1 |
71 | 18213452 | Pharmacokinetics of the CYP 3A substrate simvastatin following administration of delayed versus immediate release oral dosage forms. | 2008 Jul | 2 |
72 | 18302447 | Frequency and clinical relevance of drug interactions with lovastatin and simvastatin: an observational database study. | 2008 | 2 |
73 | 18558792 | Risk management of simvastatin or atorvastatin interactions with CYP3A4 inhibitors. | 2008 | 4 |
74 | 18783297 | General framework for the prediction of oral drug interactions caused by CYP3A4 induction from in vivo information. | 2008 | 1 |
75 | 17192506 | Effect of polymorphic CYP3A5 genotype on the single-dose simvastatin pharmacokinetics in healthy subjects. | 2007 Jan | 1 |
76 | 17304269 | [Interaction risk with statin switch]. | 2007 Feb 15 | 2 |
77 | 17381388 | Simvastatin-associated rhabdomyolysis after coadministration of macrolide antibiotics in two patients. | 2007 Apr | 2 |
78 | 17615423 | Severe rhabdomyolysis and acute renal failure secondary to concomitant use of simvastatin, amiodarone, and atazanavir. | 2007 Jul-Aug | 2 |
79 | 18220561 | Quantitative correlations among CYP3A sensitive substrates and inhibitors: literature analysis. | 2007 Dec | 1 |
80 | 16415122 | In silico and in vitro screening for inhibition of cytochrome P450 CYP3A4 by comedications commonly used by patients with cancer. | 2006 Apr | 1 |
81 | 16537817 | Simvastatin-amiodarone interaction resulting in rhabdomyolysis, azotemia, and possible hepatotoxicity. | 2006 Apr | 2 |
82 | 16580903 | Comparison of midazolam and simvastatin as cytochrome P450 3A probes. | 2006 Apr | 2 |
83 | 16581325 | Statin safety and drug interactions: clinical implications. | 2006 Apr 17 | 2 |
84 | 16581329 | Statin safety: a systematic review. | 2006 Apr 17 | 4 |
85 | 16611111 | Thienopyridines and statins: assessing a potential drug-drug interaction. | 2006 | 1 |
86 | 16714062 | Pharmacokinetic and pharmacodynamic alterations of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors: drug-drug interactions and interindividual differences in transporter and metabolic enzyme functions. | 2006 Oct | 2 |
87 | 17178259 | Drug interactions with lipid-lowering drugs: mechanisms and clinical relevance. | 2006 Dec | 2 |
88 | 15650881 | Ile118Val genetic polymorphism of CYP3A4 and its effects on lipid-lowering efficacy of simvastatin in Chinese hyperlipidemic patients. | 2005 Feb | 5 |
89 | 15679472 | Existence of a clinically relevant interaction between clopidogrel and HMG-CoA reductase inhibitors? Re-evaluating the evidence. | 2005 Feb | 1 |
90 | 15811174 | Clearance rates of cerivastatin metabolites in a patient with cerivastatin-induced rhabdomyolysis. | 2005 Apr | 1 |
91 | 15963098 | Suboptimal choices and dosing of statins at start of therapy. | 2005 Jul | 1 |
92 | 16238904 | Pharmacokinetics of telithromycin: application to dosing in the treatment of community-acquired respiratory tract infections. | 2005 Oct | 1 |
93 | 16264203 | Myonecrosis after elective percutaneous coronary intervention: effect of clopidogrel-statin interaction. | 2005 Nov | 1 |
94 | 16321621 | The role of common variants of ABCB1, CYP3A4, and CYP3A5 genes in lipid-lowering efficacy and safety of simvastatin treatment. | 2005 Nov | 1 |
95 | 12603176 | Investigation of the mutual pharmacokinetic interactions between bosentan, a dual endothelin receptor antagonist, and simvastatin. | 2003 | 1 |
96 | 12817528 | Influence of drugs interacting with CYP3A4 on the pharmacokinetics, pharmacodynamics, and safety of the prandial glucose regulator repaglinide. | 2003 Jun | 1 |
97 | 14522569 | Lipophilic statins interfere with the inhibitory effects of clopidogrel on platelet function--a flow cytometry study. | 2003 Oct | 1 |
98 | 14612892 | Effects of imatinib mesylate (STI571, Glivec) on the pharmacokinetics of simvastatin, a cytochrome p450 3A4 substrate, in patients with chronic myeloid leukaemia. | 2003 Nov 17 | 2 |
99 | 12410059 | Colchicine-induced acute myopathy in a patient with concomitant use of simvastatin. | 2002 Sep-Oct | 1 |
100 | 12433810 | Regulation of CYP2B6 and CYP3A expression by hydroxymethylglutaryl coenzyme A inhibitors in primary cultured human hepatocytes. | 2002 Dec | 1 |