Progesterone

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







30 Article(s)
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Pub. Year
#Total Relationships
1 33790108 Comparison of the Stimulatory and Inhibitory Effects of Steroid Hormones and α-Naphthoflavone on Steroid Hormone Hydroxylation Catalyzed by Human Cytochrome P450 3A Subfamilies. 2021 4
2 34196520 Structural Dynamics of Cytochrome P450 3A4 in the Presence of Substrates and Cytochrome P450 Reductase. 2021 Jul 20 1
3 32001245 Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies. 2020 Mar 30 4
4 30785734 Allosteric Interactions in Human Cytochrome P450 CYP3A4: The Role of Phenylalanine 213. 2019 Mar 12 2
5 31083930 A Covalently Attached Progesterone Molecule Outcompetes the Binding of Free Progesterone at an Allosteric Site of Cytochrome P450 3A4. 2019 Jun 19 4
6 31339834 Comparison of Steroid Hormone Hydroxylations by and Docking to Human Cytochromes P450 3A4 and 3A5. 2019 4
7 31829451 Progesterone Metabolites Inhibit the Human Ether-a-go-go-Related Gene and Predict QT Interval Length. 2019 Dec 12 2
8 30125880 Polydopamine functionalized nanoporous graphene foam as nanoreactor for efficient electrode-driven metabolism of steroid hormones. 2018 Nov 15 1
9 27995413 Is cytochrome P450 3A4 regulated by menstrual cycle hormones in control endometrium and endometriosis? 2017 Mar 2
10 28221037 Computational Investigation of Ligand Binding to the Peripheral Site in CYP3A4: Conformational Dynamics and Inhibitor Discovery. 2017 Mar 27 1
11 28339191 Allosteric Activation of Cytochrome P450 3A4 via Progesterone Bioconjugation. 2017 Apr 19 2
12 28949811 Characterization of Maternal and Fetal CYP3A-Mediated Progesterone Metabolism. 2017 Oct 1
13 25678418 Regioselective hydroxylation of steroid hormones by human cytochromes P450. 2015 May 1
14 26066995 Anion-Dependent Stimulation of CYP3A4 Monooxygenase. 2015 Jul 7 2
15 24256945 Two surfaces of cytochrome b5 with major and minor contributions to CYP3A4-catalyzed steroid and nifedipine oxygenation chemistries. 2014 Jan 1 1
16 22837389 Isoform-specific regulation of cytochromes P450 expression by estradiol and progesterone. 2013 Feb 1
17 23223499 Induction of hepatic CYP3A enzymes by pregnancy-related hormones: studies in human hepatocytes and hepatic cell lines. 2013 Feb 1
18 22194603 Peripheral ligand-binding site in cytochrome P450 3A4 located with fluorescence resonance energy transfer (FRET). 2012 Feb 24 1
19 18957504 Extraadrenal 21-hydroxylation by CYP2C19 and CYP3A4: effect on 21-hydroxylase deficiency. 2009 Jan 1
20 19189363 Cooperative effects on radical recombination in CYP3A4-catalyzed oxidation of the radical clock beta-thujone. 2009 Mar 2 1
21 19414330 Flexible structure of cytochrome P450: promiscuity of ligand binding in the CYP3A4 heme pocket. 2009 Mar 1
22 16490811 Use of omeprazole as a CYP3A probe drug: effect of sex and menstrual cycle phase on CYP3A activity in healthy Caucasian adults. 2006 Mar 1
23 16190729 Structural and dynamical basis of broad substrate specificity, catalytic mechanism, and inhibition of cytochrome P450 3A4. 2005 Oct 5 2
24 15256616 Crystal structures of human cytochrome P450 3A4 bound to metyrapone and progesterone. 2004 Jul 30 2
25 12464250 Structure-function relationships of rat liver CYP3A9 to its human liver orthologs: site-directed active site mutagenesis to a progesterone dihydroxylase. 2003 Jan 1 1
26 12781333 An amperometric biosensor with human CYP3A4 as a novel drug screening tool. 2003 Jun 1 1
27 12893521 In vitro activation of 7-benzyloxyresorufin O-debenzylation and nifedipine oxidation in human liver microsomes. 2003 Jul 2
28 10773032 Dual role of human cytochrome P450 3A4 residue Phe-304 in substrate specificity and cooperativity. 2000 May 1
29 9667077 Contribution of human hepatic cytochrome P450 isoforms to regioselective hydroxylation of steroid hormones. 1998 Jun 4
30 8010982 Human liver carbamazepine metabolism. Role of CYP3A4 and CYP2C8 in 10,11-epoxide formation. 1994 Jun 1 4