| 1 |
35094507 | Unique Oxidative Metabolism of Bufalin Generates Two Reactive Metabolites That Strongly Inactivate Human Cytochrome P450 3A. | 2022 Mar 10 |
1 |
| 2 |
35104412 | Dietary Inhibitors of CYP3A4 Are Revealed Using Virtual Screening by Using a New Deep-Learning Classifier. | 2022 Mar 2 |
1 |
| 3 |
35351776 | Reevaluate In Vitro CYP3A Index Reactions of Benzodiazepines and Steroids between Humans and Dogs. | 2022 Jun |
1 |
| 4 |
33449875 | Kinetics of cytochrome P450 3A4 inhibition by heterocyclic drugs defines a general sequential multistep binding process. | 2021 Jan-Jun |
1 |
| 5 |
34396687 | In vitro assessments predict that CYP3A4 contributes to a greater extent than CYP3A5 to prednisolone clearance. | 2021 Dec |
1 |
| 6 |
32001245 | Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies. | 2020 Mar 30 |
2 |
| 7 |
32656158 | Development and validation of a method for the simultaneous quantification of endogenous steroids metabolized by CYP3A. | 2020 Jun |
1 |
| 8 |
32848756 | The Clinical Impact of the C0/D Ratio and the CYP3A5 Genotype on Outcome in Tacrolimus Treated Kidney Transplant Recipients. | 2020 |
1 |
| 9 |
32967779 | Applications of a grid-based CYP3A4 Template system to understand the interacting mechanisms of large-size ligands; part 4 of CYP3A4 Template study. | 2020 Dec |
1 |
| 10 |
29120670 | Correlation Between Steroid-Induced Osteonecrosis of The Femoral Head and Hepatic CYP3A Activity: A Systematic Review and Meta-Analysis. | 2019 Mar |
7 |
| 11 |
30218411 | Correlations between CYP3A4 polymorphism and susceptibility to breast cancer in Chinese Han population. | 2019 Feb |
1 |
| 12 |
30287909 | Polymorphisms at phase I-metabolizing enzyme and hormone receptor loci influence the response to anti-TNF therapy in rheumatoid arthritis patients. | 2019 Feb |
1 |
| 13 |
31212673 | A Robust Approach for Identification of Cancer Biomarkers and Candidate Drugs. | 2019 Jun 11 |
1 |
| 14 |
31339834 | Comparison of Steroid Hormone Hydroxylations by and Docking to Human Cytochromes P450 3A4 and 3A5. | 2019 |
6 |
| 15 |
31563329 | Solving the interactions of steroidal ligands with CYP3A4 using a grid-base template system. | 2019 Dec |
6 |
| 16 |
29958895 | Steroid bioconjugation to a CYP3A4 allosteric site and its effect on substrate binding and coupling efficiency. | 2018 Sep 1 |
3 |
| 17 |
30125880 | Polydopamine functionalized nanoporous graphene foam as nanoreactor for efficient electrode-driven metabolism of steroid hormones. | 2018 Nov 15 |
1 |
| 18 |
30336495 | The Influence of CYP3A4 Polymorphism in Sex Steroids as a Risk Factor for Breast Cancer. | 2018 Nov |
1 |
| 19 |
27995413 | Is cytochrome P450 3A4 regulated by menstrual cycle hormones in control endometrium and endometriosis? | 2017 Mar |
2 |
| 20 |
28060049 | Ritonavir and Topical Ocular Corticosteroid Induced Cushing's Syndrome in an Adolescent With HIV-1 Infection. | 2017 May |
1 |
| 21 |
28458904 | Fluticasone furoate induced iatrogenic Cushing syndrome in a pediatric patient receiving anti-retroviral therapy. | 2017 |
1 |
| 22 |
26774838 | The use of isomeric testosterone dimers to explore allosteric effects in substrate binding to cytochrome P450 CYP3A4. | 2016 May |
1 |
| 23 |
27855510 | UHPLC-MS/MS bioanalysis of urinary DHEA, cortisone and their hydroxylated metabolites as potential biomarkers for CYP3A-mediated drug-drug interactions. | 2016 Dec |
1 |
| 24 |
27858915 | Genetic polymorphisms of CYP3A4 among Chinese patients with steroid-induced osteonecrosis of the femoral head. | 2016 Nov |
5 |
| 25 |
25678418 | Regioselective hydroxylation of steroid hormones by human cytochromes P450. | 2015 May |
2 |
| 26 |
26114223 | Progressive decline in tacrolimus clearance after renal transplantation is partially explained by decreasing CYP3A4 activity and increasing haematocrit. | 2015 Sep |
1 |
| 27 |
26133240 | A Mechanism-Based Model for the Prediction of the Metabolic Sites of Steroids Mediated by Cytochrome P450 3A4. | 2015 Jun 30 |
3 |
| 28 |
24256945 | Two surfaces of cytochrome b5 with major and minor contributions to CYP3A4-catalyzed steroid and nifedipine oxygenation chemistries. | 2014 Jan 1 |
1 |
| 29 |
24732405 | Practical treatment using mitotane for adrenocortical carcinoma. | 2014 Jun |
1 |
| 30 |
23384967 | Comparative analysis of human CYP3A4 and rat CYP3A1 induction and relevant gene expression by bisphenol A and diethylstilbestrol: implications for toxicity testing paradigms. | 2013 Jun |
1 |
| 31 |
23851904 | GC-MS-based quantitative signatures of cytochrome P450-mediated steroid oxidation induced by rifampicin. | 2013 Aug |
3 |
| 32 |
22053102 | Oral rifampin utilisation for the treatment of chronic multifocal central serous retinopathy. | 2012 Jan |
1 |
| 33 |
21698408 | Correlation between docetaxel-induced skin toxicity and the use of steroids and Hâ‚‚ blockers: a multi-institution survey. | 2011 Nov |
1 |
| 34 |
21742782 | Acetyl tributyl citrate, the most widely used phthalate substitute plasticizer, induces cytochrome p450 3a through steroid and xenobiotic receptor. | 2011 Oct |
2 |
| 35 |
21750466 | Differential association of cytochrome P450 3A4 genotypes with onsets of breast tumors in African American versus Caucasian patients. | 2011 Oct |
1 |
| 36 |
21854345 | Inhaled fluticasone causes iatrogenic cushing's syndrome in patients treated with Ritonavir. | 2011 Oct |
1 |
| 37 |
21863748 | [The influence of vitamin B group on monooxygenase activity of cytochrome P450 3A4: pharmacokinetics and electro analysis of catalytic properties]. | 2011 May-Jun |
1 |
| 38 |
20188793 | Restoration of mutant cytochrome P450 reductase activity by external flavin. | 2010 Jun 10 |
1 |
| 39 |
20456080 | Triamcinolone acetonide induced secondary adrenal insufficiency related to impaired CYP3A4 metabolism by coadministration of nefazodone. | 2010 Jul |
1 |
| 40 |
20505544 | Effect of hormone metabolism genotypes on steroid hormone levels and menopausal symptoms in a prospective population-based cohort of women experiencing the menopausal transition. | 2010 Sep-Oct |
1 |
| 41 |
20621111 | Cytochrome P450 3A gene variation, steroid hormone serum levels and prostate cancer--The Rotterdam Study. | 2010 Dec |
2 |
| 42 |
20715157 | The frameshift polymorphism CYP3A43_74_delA is associated with poor differentiation of breast tumors. | 2010 Dec 1 |
1 |
| 43 |
20924570 | Systemic uptake of miconazole during vaginal suppository use and effect on CYP1A2 and CYP3A4 associated enzyme activities in women. | 2010 Dec |
1 |
| 44 |
19020497 | The CYP3A4*18 genotype in the cytochrome P450 3A4 gene, a rapid metabolizer of sex steroids, is associated with low bone mineral density. | 2009 Mar |
5 |
| 45 |
19299527 | Ligand diversity of human and chimpanzee CYP3A4: activation of human CYP3A4 by lithocholic acid results from positive selection. | 2009 Jun |
1 |
| 46 |
19409404 | Toxicogenomic effects common to triazole antifungals and conserved between rats and humans. | 2009 Jul 1 |
1 |
| 47 |
18259987 | Expression, activity and regulation of CYP3A in human and rodent brain. | 2008 |
1 |
| 48 |
18420779 | Comparative analysis of CYP3A heteroactivation by steroid hormones and flavonoids in different in vitro systems and potential in vivo implications. | 2008 Jul |
1 |
| 49 |
17035600 | Pregnane X receptor-dependent induction of the CYP3A4 gene by o,p'-1,1,1,-trichloro-2,2-bis (p-chlorophenyl)ethane. | 2007 Jan |
1 |
| 50 |
17204458 | Theoretical calculation of triazolam hydroxylation and endogenous steroid inhibition in the active site of CYP3A4. | 2007 Feb |
1 |