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35184385 | Gene Expression Profiling of 1α,25(OH)2 D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes. | 2022 May |
2 |
| 2 |
33572963 | Pharmacokinetic Estimation Models-based Approach to Predict Clinical Implications for CYP Induction by Calcitriol in Human Cryopreserved Hepatocytes and HepaRG Cells. | 2021 Jan 29 |
2 |
| 3 |
33947307 | Evaluation system for cell-permeable CYP3A4 inhibitory activity using 1α,25-dihydroxy-vitamin D3-induced intestinal cell lines. | 2021 Jul |
1 |
| 4 |
31884012 | Successful Prediction of Human Pharmacokinetics After Oral Administration by Optimized Physiologically Based Pharmacokinetics Approach and Permeation Assay Using Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Cells. | 2020 Apr |
2 |
| 5 |
31867158 | Role of vitamin D receptor in the regulation of CYP3A gene expression. | 2019 Nov |
3 |
| 6 |
30270266 | [Development of an In Vitro System for Evaluating Intestinal Drug Disposition Using Human Induced Pluripotent Stem Cell-Derived Intestinal Epithelial Cells]. | 2018 |
1 |
| 7 |
28418012 | CYP3A4 is a crosslink between vitamin D and calcineurin inhibitors in solid organ transplant recipients: implications for bone health. | 2017 Dec |
2 |
| 8 |
26433738 | Factors associated with 1,25-dihydroxyvitamin D3 concentrations in liver transplant recipients: a prospective observational longitudinal study. | 2016 Apr |
1 |
| 9 |
26966071 | Modeling of drug-mediated CYP3A4 induction by using human iPS cell-derived enterocyte-like cells. | 2016 Apr 15 |
1 |
| 10 |
27161454 | Inhibition of mitogen-activated protein kinase kinase, DNA methyltransferase, and transforming growth factor-β promotes differentiation of human induced pluripotent stem cells into enterocytes. | 2016 Jun |
1 |
| 11 |
25410880 | Simultaneous evaluation of human CYP3A4 and ABCB1 induction by reporter assay in LS174T cells, stably expressing their reporter genes. | 2015 Apr |
1 |
| 12 |
25650381 | Generation of enterocyte-like cells with pharmacokinetic functions from human induced pluripotent stem cells using small-molecule compounds. | 2015 Apr |
2 |
| 13 |
26559489 | Generation of enterocyte-like cells from human induced pluripotent stem cells for drug absorption and metabolism studies in human small intestine. | 2015 Nov 12 |
3 |
| 14 |
24269662 | Abiraterone inhibits 1α,25-dihydroxyvitamin D3 metabolism by CYP3A4 in human liver and intestine in vitro. | 2014 Oct |
2 |
| 15 |
24486455 | Ginsenoside-mediated blockade of 1α,25-dihydroxyvitamin D3 inactivation in human liver and intestine in vitro. | 2014 May |
1 |
| 16 |
21925256 | Andrographolide inhibits the expression and metabolic activity of cytochrome P450 3A4 in the modified Caco-2 cells. | 2012 Jun 1 |
1 |
| 17 |
22562045 | Human PXR-mediated induction of intestinal CYP3A4 attenuates 1α,25-dihydroxyvitamin D₃ function in human colon adenocarcinoma LS180 cells. | 2012 Aug 1 |
1 |
| 18 |
22687401 | Establishment of a stable human cell line, HPL-A3, for use in reporter gene assays of cytochrome P450 3A inducers. | 2012 |
1 |
| 19 |
22984610 | Astemizole synergizes calcitriol antiproliferative activity by inhibiting CYP24A1 and upregulating VDR: a novel approach for breast cancer therapy. | 2012 |
2 |
| 20 |
23107701 | Anti-inflammatory effect and modulation of cytochrome P450 activities by Artemisia annua tea infusions in human intestinal Caco-2 cells. | 2012 Sep 15 |
1 |
| 21 |
20016682 | Vitamin d levels and lipid response to atorvastatin. | 2010 |
1 |
| 22 |
18364084 | [Induction of CYP3A4 by 1alpha,25-dihydroxyvitamin D3 in HepG2 cells]. | 2008 Mar |
5 |
| 23 |
16691293 | Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. | 2006 Jun |
2 |
| 24 |
15205382 | C-jun N-terminal kinase modulates 1,25-dihydroxyvitamin D3-induced cytochrome P450 3A4 gene expression. | 2004 Jul |
1 |
| 25 |
12641633 | Calcitriol regulates the expression of the genes encoding the three key vitamin D3 hydroxylases and the drug-metabolizing enzyme CYP3A4 in the human fetal intestine. | 2003 Apr |
2 |
| 26 |
14575816 | Role of c-Myc in nitric oxide-mediated suppression of cytochrome P450 3A4. | 2003 Nov 21 |
3 |
| 27 |
11782903 | Investigation of the coordinated functional activities of cytochrome P450 3A4 and P-glycoprotein in limiting the absorption of xenobiotics in Caco-2 cells. | 2002 Jan |
1 |
| 28 |
12147248 | Alteration of cellular phosphorylation state affects vitamin D receptor-mediated CYP3A4 mRNA induction in Caco-2 cells. | 2002 Aug 9 |
2 |
| 29 |
11602520 | Induction of CYP3A4 by 1 alpha,25-dihydroxyvitamin D3 is human cell line-specific and is unlikely to involve pregnane X receptor. | 2001 Nov |
2 |
| 30 |
11723248 | Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3. | 2001 Dec |
3 |
| 31 |
11745731 | CYP3A4, CYP3A5, and MDR1 in human small and large intestinal cell lines suitable for drug transport studies. | 2001 Nov |
1 |
| 32 |
10993481 | Inhibitory effect of nitric oxide on the induction of cytochrome P450 3A4 mRNA by 1,25-dihydroxyvitamin D3 in Caco-2 cells. | 2000 Sep |
5 |
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10215697 | First-pass midazolam metabolism catalyzed by 1alpha,25-dihydroxy vitamin D3-modified Caco-2 cell monolayers. | 1999 May |
1 |
| 34 |
9145912 | Expression of enzymatically active CYP3A4 by Caco-2 cells grown on extracellular matrix-coated permeable supports in the presence of 1alpha,25-dihydroxyvitamin D3. | 1997 May |
2 |