15 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 32331852 | Versatile applicability of a grid-based CYP3A4 Template to understand the interacting mechanisms with the small-size ligands; part 3 of CYP3A4 Template study. | 2020 Jun | 1 |
2 | 31480231 | Structural Insights into the Interaction of Cytochrome P450 3A4 with Suicide Substrates: Mibefradil, Azamulin and 6',7'-Dihydroxybergamottin. | 2019 Aug 30 | 2 |
3 | 21447734 | Mechanism-based inactivation of cytochrome P450 3A4 by mibefradil through heme destruction. | 2011 Jul | 6 |
4 | 24479199 | ML368 Identification of Imidazopyridines as Selective Inhibitors of the Cytochrome P450 Enzyme CYP3A4 | 2010 | 2 |
5 | 18411403 | The mibefradil derivative NNC55-0396, a specific T-type calcium channel antagonist, exhibits less CYP3A4 inhibition than mibefradil. | 2008 Jul | 2 |
6 | 18473851 | Potential strategies for minimizing mechanism-based inhibition of cytochrome P450 3A4. | 2008 | 1 |
7 | 17392390 | Risk assessment for drug-drug interaction caused by metabolism-based inhibition of CYP3A using automated in vitro assay systems and its application in the early drug discovery process. | 2007 Jul | 1 |
8 | 15860655 | Automated screening with confirmation of mechanism-based inactivation of CYP3A4, CYP2C9, CYP2C19, CYP2D6, and CYP1A2 in pooled human liver microsomes. | 2005 Aug | 1 |
9 | 10640508 | Drug interactions with calcium channel blockers: possible involvement of metabolite-intermediate complexation with CYP3A. | 2000 Feb | 2 |
10 | 10901697 | Mibefradil is a P-glycoprotein substrate and a potent inhibitor of both P-glycoprotein and CYP3A in vitro. | 2000 Aug | 5 |
11 | 10215754 | Metabolic interactions between mibefradil and HMG-CoA reductase inhibitors: an in vitro investigation with human liver preparations. | 1999 Mar | 8 |
12 | 10226769 | Mibefradil, a potent CYP3A inhibitor, does not alter pravastatin pharmacokinetics. | 1999 | 1 |
13 | 10546924 | Mibefradil but not isradipine substantially elevates the plasma concentrations of the CYP3A4 substrate triazolam. | 1999 Oct | 3 |
14 | 9681729 | Pharmacokinetic interaction between oral cyclosporin and mibefradil in stabilized post-renal-transplant patients. | 1998 Jul | 1 |
15 | 9811158 | Single- and multiple-dose mibefradil pharmacokinetics in normal and hypertensive subjects. | 1998 Sep | 2 |