saxagliptin

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







9 Article(s)
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Pub. Year
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1 33961299 Effects of 27 CYP3A4 protein variants on saxagliptin metabolism in vitro. 2022 Feb 4
2 35247279 Use of Physiologically Based Pharmacokinetic Modeling to Evaluate the Impact of Chronic Kidney Disease on CYP3A4-Mediated Metabolism of Saxagliptin. 2022 Mar 5 6
3 24746233 The pharmacokinetic considerations and adverse effects of DPP-4 inhibitors [corrected]. 2014 Jun 1
4 23137182 Saxagliptin overview: special focus on safety and adverse effects. 2013 Jan 1
5 22496391 Characterization of the in vitro and in vivo metabolism and disposition and cytochrome P450 inhibition/induction profile of saxagliptin in human. 2012 Jul 1
6 21651615 Effect of rifampicin on the pharmacokinetics and pharmacodynamics of saxagliptin, a dipeptidyl peptidase-4 inhibitor, in healthy subjects. 2011 Jul 1
7 22287853 Two-way pharmacokinetic interaction studies between saxagliptin and cytochrome P450 substrates or inhibitors: simvastatin, diltiazem extended-release, and ketoconazole. 2011 3
8 20590741 Pharmacokinetics of dipeptidylpeptidase-4 inhibitors. 2010 Aug 1
9 20690781 Dipeptidylpeptidase-4 inhibitors (gliptins): focus on drug-drug interactions. 2010 Sep 3