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10923859 | Identification of enzymes responsible for rifalazil metabolism in human liver microsomes. | 2000 Jun |
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10981246 | Drug interaction between St. John's wort and cyclosporine. | 2000 Sep |
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11009048 | Frequency of cytochrome P450 3A4 variant genotype in transplant population and lack of association with cyclosporin clearance. | 2000 Aug |
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11038163 | In vitro evaluation of the disposition of A novel cysteine protease inhibitor. | 2000 Nov |
3 |
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11067738 | Studies on the interactions between drugs and estrogen: analytical method for prediction system of gynecomastia induced by drugs on the inhibitory metabolism of estradiol using Escherichia coli coexpressing human CYP3A4 with human NADPH-cytochrome P450 reductase. | 2000 Nov 15 |
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11121733 | Can oral midazolam predict oral cyclosporine disposition? | 2000 Nov |
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11151744 | Effects of metronidazole on midazolam metabolism in vitro and in vivo. | 2000 Nov |
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11180020 | Lack of effect of St John's Wort on carbamazepine pharmacokinetics in healthy volunteers. | 2000 Dec |
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10092957 | Clinical pharmacokinetics of docetaxel. | 1999 Feb |
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10215697 | First-pass midazolam metabolism catalyzed by 1alpha,25-dihydroxy vitamin D3-modified Caco-2 cell monolayers. | 1999 May |
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10385214 | Halofantrine metabolism in microsomes in man: major role of CYP 3A4 and CYP 3A5. | 1999 Apr |
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10411567 | Use of the steroid derivative RPR 106541 in combination with site-directed mutagenesis for enhanced cytochrome P-450 3A4 structure/function analysis. | 1999 Aug |
1 |
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10496299 | Clinical pharmacokinetics of troglitazone. | 1999 Aug |
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10503812 | Cyclosporin pharmacokinetics in the elderly. | 1999 Sep |
2 |
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10513779 | Concomitant use of cytochrome P450 3A4 inhibitors and simvastatin. | 1999 Oct 1 |
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9469504 | Interactions between cyclosporine and newer antidepressant medications. | 1998 Feb |
1 |
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9698296 | The multidrug resistance modulator valspodar (PSC 833) is metabolized by human cytochrome P450 3A. Implications for drug-drug interactions and pharmacological activity of the main metabolite. | 1998 Aug |
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9749227 | [Calcium inhibitors in the management of hypertensive patients on cyclosporine]. | 1998 Apr |
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9855331 | Pharmacokinetic drug interactions of vinca alkaloids: summary of case reports. | 1998 Nov-Dec |
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9402948 | Long-term primary cultures of adult human hepatocytes. | 1997 Nov 6 |
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10837554 | Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction. | 1997 Sep 15 |
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10837558 | Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery. | 1997 Sep 15 |
3 |
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8549033 | Comparison of the dapsone recovery ratio and the erythromycin breath test as in vivo probes of CYP3A activity in patients with rheumatoid arthritis receiving cyclosporine. | 1996 Jan |
3 |
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8689812 | Itraconazole drastically increases plasma concentrations of lovastatin and lovastatin acid. | 1996 Jul |
1 |
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8849485 | Drug interactions and interindividual variability of ciclosporin metabolism in the small intestine. | 1996 Mar |
3 |
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8855178 | Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin. | 1996 Oct |
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8857552 | Erythromycin breath test and clinical transplantation. | 1996 Aug |
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8885130 | Possible interaction between cyclosporine and glibenclamide in posttransplant diabetic patients. | 1996 Oct |
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7473140 | Variability in human cytochrome P450 paclitaxel metabolism. | 1995 Nov |
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7628296 | Human liver cytochrome P4503A biotransformation of the cyclosporin derivative SDZ IMM 125. | 1995 Mar |
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7895601 | Terfenadine metabolism in human liver. In vitro inhibition by macrolide antibiotics and azole antifungals. | 1994 Nov-Dec |
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7965756 | Use of midazolam as a human cytochrome P450 3A probe: II. Characterization of inter- and intraindividual hepatic CYP3A variability after liver transplantation. | 1994 Oct |
2 |
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8013282 | The polymorphic cytochrome P-4502D6 is involved in the metabolism of both 5-hydroxytryptamine antagonists, tropisetron and ondansetron. | 1994 Mar-Apr |
2 |
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8114683 | O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4. | 1994 Feb |
1 |
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8119047 | Pharmacokinetic drug interactions with antimicrobial agents. | 1993 Dec |
1 |
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8265621 | Human cytochrome P450 3A4: enzymatic properties of a purified recombinant fusion protein containing NADPH-P450 reductase. | 1993 Dec 15 |
1 |
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1424421 | Erythromycin breath test predicts oral clearance of cyclosporine in kidney transplant recipients. | 1992 Nov |
1 |
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1643634 | Role of cytochrome P-450 from the human CYP3A gene family in the potentiation of morpholino doxorubicin by human liver microsomes. | 1992 Aug 15 |
1 |