Cyclosporine

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







192 Article(s)
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1 33974505 Association of polymorphism of CYP3A4, ABCB1, ABCC2, ABCG2, NFKB1, POR, and PXR with the concentration of cyclosporin A in allogeneic haematopoietic stem cell transplantation recipients. 2021 Jul 3
2 33991364 Increased systemic exposure of once-daily tacrolimus in renal transplant recipients on marine omega-3 fatty acid supplementation. 2021 Jul 1
3 34306041 CYP3A422 Genotyping in Clinical Practice: Ready for Implementation? 2021 1
4 31248333 Interaction Between Cyclosporine and Palbociclib in a Renal Transplant Patient: Case Report and Pharmacokinetic Perspective. 2020 Dec 1
5 32162881 Severe Anaphylaxis During Allogeneic Hematopoietic Stem Cell Transplantation in a Patient with Aplastic Anemia: Case Report of Individualized Pharmaceutical Care and Literature Review. 2020 Mar 1 1
6 32222391 Worsening of Kidney Transplant Function During 2-Year Follow-up Is Associated With the Genetic Variants of CYP3A4, MDR1, and UGT1A9. 2020 Oct 1
7 32682934 Incorporating nonlinear kinetics to improve predictive performance of population pharmacokinetic models for ciclosporin in adult renal transplant recipients: A comparison of modelling strategies. 2020 Oct 1 2
8 32967779 Applications of a grid-based CYP3A4 Template system to understand the interacting mechanisms of large-size ligands; part 4 of CYP3A4 Template study. 2020 Dec 1
9 30378493 Metabolic Pathway of Cyclosporine A and Its Correlation with Nephrotoxicity. 2019 1
10 30799432 Effect of Multidrug-Resistant 1 (MDR1) and CYP3A4*1B Polymorphisms on Cyclosporine-Based Immunosuppressive Therapy in Renal Transplant Patients. 2019 Feb 25 3
11 30799725 The interleukin-17 G-197A polymorphism is associated with cyclosporine metabolism and transplant rejection in liver transplant recipients. 2019 Apr 1
12 30912163 Perpetrator effects of ciclosporin (P-glycoprotein inhibitor) and its combination with fluconazole (CYP3A inhibitor) on the pharmacokinetics of rivaroxaban in healthy volunteers. 2019 Jul 3
13 31156436 A Single Dose of Baicalin Has No Clinically Significant Effect on the Pharmacokinetics of Cyclosporine A in Healthy Chinese Volunteers. 2019 1
14 31261526 Correlation between gene polymorphism and blood concentration of calcineurin inhibitors in renal transplant recipients: An overview of systematic reviews. 2019 Jun 2
15 31385766 Association Between CYP3A4 and CYP3A5 Genotypes and Cyclosporine's Blood Levels and Doses among Jordanian Kidney Transplanted Patients. 2019 6
16 29678659 Association of CYP3A4*1B genotype with Cyclosporin A pharmacokinetics in renal transplant recipients: A meta-analysis. 2018 Jul 20 9
17 29712725 Quantitative Analysis of Complex Drug-Drug Interactions between Cerivastatin and Metabolism/Transport Inhibitors Using Physiologically Based Pharmacokinetic Modeling. 2018 Jul 1
18 29801578 The Pharmacogenetics of Immune-Modulating Therapy. 2018 1
19 30044899 Amenamevir: Studies of Potential CYP3A-Mediated Pharmacokinetic Interactions With Midazolam, Cyclosporine, and Ritonavir in Healthy Volunteers. 2018 Nov 1
20 28479356 Quantitative Analysis of Complex Drug-Drug Interactions Between Repaglinide and Cyclosporin A/Gemfibrozil Using Physiologically Based Pharmacokinetic Models With In Vitro Transporter/Enzyme Inhibition Data. 2017 Sep 1
21 28616429 Evaluation of the Interaction of Intravenous and Oral Voriconazole with Oral Cyclosporine in Iranian HSCT Patients. 2017 Apr-Jun 2
22 28722255 Drug-drug interactions between triazole antifungal agents used to treat invasive aspergillosis and immunosuppressants metabolized by cytochrome P450 3A4. 2017 Oct 1
23 28952408 Influence of CYP3A and ABCB1 polymorphisms on cyclosporine concentrations in renal transplant recipients. 2017 Nov 2
24 29135906 Effect of Age and Allele Variants of CYP3A5, CYP3A4, and POR Genes on the Pharmacokinetics of Cyclosporin A in Pediatric Renal Transplant Recipients From Serbia. 2017 Dec 5
25 26259716 Mechanistic understanding of the nonlinear pharmacokinetics and intersubject variability of simeprevir: A PBPK-guided drug development approach. 2016 Feb 1
26 26353895 Drug-Drug Interactions with the NS3/4A Protease Inhibitor Simeprevir. 2016 Feb 2
27 26385839 Physiologically-Based Pharmacokinetic Modeling of Macitentan: Prediction of Drug-Drug Interactions. 2016 Mar 1
28 26713664 Targeting myocardial reperfusion injuries with cyclosporine in the CIRCUS Trial - pharmacological reasons for failure. 2016 Apr 4
29 26912097 Clinical determinants of calcineurin inhibitor disposition: a mechanistic review. 2016 2
30 26950050 CYP3A activity: towards dose adaptation to the individual. 2016 May 1
31 27310200 Risk Assessment of Drug-Drug Interactions of Calcineurin Inhibitors Affecting Sirolimus Pharmacokinetics in Renal Transplant Patients. 2016 Oct 1
32 27519420 Metabolic complete response with vinflunine as second-line therapy in a kidney-transplanted patient with advanced urothelial carcinoma: a case report. 2016 Aug 12 1
33 25240575 Impact of CYP3A4 and MDR1 gene (G2677T) polymorphisms on dose requirement of the cyclosporine in renal transplant Egyptian recipients. 2015 Jan 9
34 25512016 Increased dosage of cyclosporine induces myopathy with increased seru creatine kinase in an elderly patient on chronic statin therapy. 2015 Apr 1
35 25644970 Association of CYP3A variants with kidney transplant outcomes. 2015 May 1
36 25976223 CYP3A4∗18B and CYP3A5∗3 polymorphisms contribute to pharmacokinetic variability of cyclosporine among healthy Chinese subjects. 2015 Aug 30 3
37 26150050 Evaluation of 6β-Hydroxycortisol and 6β-Hydroxycortisone as Biomarkers for Cytochrome P450 3A Activity: Insight into Their Predictive Value for Estimating Oral Immunosuppressant Metabolism. 2015 Oct 1
38 26271661 Personalizing initial calcineurin inhibitor dosing by adjusting to donor CYP3A-status in liver transplant patients. 2015 Dec 2
39 26301745 Transport and uptake of clausenamide enantiomers in CYP3A4-transfected Caco-2 cells: An insight into the efflux-metabolism alliance. 2015 Nov 1 1
40 26817280 A non-invasive CYP3A4 biomarker and body mass index predict cyclosporine dosage requirements in Chinese renal transplant recipients. 2015 Dec 3
41 24369269 Successful telaprevir treatment in combination of cyclosporine against recurrence of hepatitis C in the Japanese liver transplant patients. 2014 1
42 24522145 Effect of CYP3A4*22, CYP3A5*3, and CYP3A Combined Genotypes on Cyclosporine, Everolimus, and Tacrolimus Pharmacokinetics in Renal Transplantation. 2014 Feb 12 1
43 24527031 Cyclosporine and herbal supplement interactions. 2014 1
44 24658827 The influence of CYP3A, PPARA, and POR genetic variants on the pharmacokinetics of tacrolimus and cyclosporine in renal transplant recipients. 2014 Jun 4
45 24691060 Association of CYP3A4*18B and CYP3A5*3 polymorphism with cyclosporine-related liver injury in Chinese renal transplant recipients. 2014 Jun 5
46 24739665 Pharmacokinetic drug interaction between cyclosporine and imatinib in bone marrow transplant children and model-based reappraisal of imatinib drug interaction profile. 2014 Dec 1
47 24739669 CYP3A5*3 and POR*28 genetic variants influence the required dose of tacrolimus in heart transplant recipients. 2014 Dec 1
48 24990333 The proton pump inhibitor lansoprazole, but not rabeprazole, the increased blood concentrations of calcineurin inhibitors in Japanese patients with connective tissue diseases. 2014 1
49 25125033 [Lacidipine efficacy and safety for high blood pressure treatment in pediatric oncohematology]. 2014 Oct 1
50 25280976 Pharmacokinetic drug-drug interaction of calcium channel blockers with cyclosporine in hematopoietic stem cell transplant children. 2014 Dec 2