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32691891 | Physiologically-Based Pharmacokinetic Modeling Characterizes the CYP3A-Mediated Drug-Drug Interaction Between Fluconazole and Sildenafil in Infants. | 2021 Jan |
1 |
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33348240 | The utility of CYP3A activity endogenous markers for evaluating drug-drug interaction between sildenafil and CYP3A inhibitors in healthy subjects. | 2021 Feb |
2 |
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34199328 | Changes in the Pharmacokinetics and Pharmacodynamics of Sildenafil in Cigarette and Cannabis Smokers. | 2021 Jun 13 |
3 |
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32613761 | The endothelin receptor antagonist macitentan for the treatment of pulmonary arterial hypertension: A cross-species comparison of its cytochrome P450 induction pattern. | 2020 Aug |
1 |
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33262574 | Functional Measurement of CYP2C9 and CYP3A4 Allelic Polymorphism on Sildenafil Metabolism. | 2020 |
7 |
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31475367 | Population pharmacokinetics of sildenafil in extremely premature infants. | 2019 Dec |
1 |
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28440343 | CYP3A4 genotype is associated with sildenafil concentrations in patients with heart failure with preserved ejection fraction. | 2018 Apr |
4 |
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29110626 | The Rationale for Repurposing Sildenafil for Lung Cancer Treatment. | 2018 |
1 |
| 9 |
28067999 | Evaluation of Pharmacokinetic Interactions Between Lesinurad, a New Selective Urate Reabsorption Inhibitor, and CYP Enzyme Substrates Sildenafil, Amlodipine, Tolbutamide, and Repaglinide. | 2017 Jul |
1 |
| 10 |
25693997 | A Phase I study to assess the safety, tolerability and pharmacokinetic profile of boceprevir and sildenafil when dosed separately and together, in healthy male volunteers. | 2015 |
1 |
| 11 |
25744459 | Contribution of CYP3A isoforms to dealkylation of PDE5 inhibitors: a comparison between sildenafil N-demethylation and tadalafil demethylenation. | 2015 |
4 |
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1 |
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20203109 | Selection of alternative CYP3A4 probe substrates for clinical drug interaction studies using in vitro data and in vivo simulation. | 2010 Jun |
1 |
| 14 |
19958586 | Effect of hepatic CYP inhibitors on the metabolism of sildenafil and formation of its metabolite, N-desmethylsildenafil, in rats in vitro and in vivo. | 2009 Dec |
2 |
| 15 |
18308836 | The contributions of cytochromes P450 3A4 and 3A5 to the metabolism of the phosphodiesterase type 5 inhibitors sildenafil, udenafil, and vardenafil. | 2008 Jun |
2 |
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18997493 | The use of phosphodiesterase 5 inhibitors with concomitant medications. | 2008 Sep |
1 |
| 17 |
16372380 | The effect of ciprofloxacin and clarithromycin on sildenafil oral bioavailability in human volunteers. | 2006 Mar |
2 |
| 18 |
15865259 | Effects of combined treatment with sildenafil and itraconazole on the cardiovascular system in telemetered conscious dogs. | 2005 |
1 |
| 19 |
11890373 | Myocardial infarction following the combined recreational use of Viagra and cannabis. | 2002 Mar |
1 |
| 20 |
12058245 | Interactions between drugs for erectile dysfunction and drugs for cardiovascular disease. | 2002 Jun |
1 |
| 21 |
12497749 | [Interaction between sildenafil and calcineurin inhibitors in renal transplant recipients with erectile dysfunction]. | 2002 |
1 |
| 22 |
11219477 | Sildenafil citrate: a therapeutic update. | 2001 Jan |
2 |
| 23 |
11298070 | Identification of the cytochrome P450 enzymes involved in the N-demethylation of sildenafil. | 2001 Mar |
4 |
| 24 |
10725306 | In vitro biotransformation of sildenafil (Viagra): identification of human cytochromes and potential drug interactions. | 2000 Apr |
3 |
| 25 |
10930961 | Pharmacokinetic interactions between sildenafil and saquinavir/ritonavir. | 2000 Aug |
1 |
| 26 |
10546851 | Interaction of sildenafil and indinavir when co-administered to HIV-positive patients. | 1999 Oct 22 |
1 |
| 27 |
9916601 | Safety and efficacy of sildenafil citrate in the treatment of male erectile dysfunction. | 1998 Nov-Dec |
1 |