Quetiapine Fumarate

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







37 Article(s)
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1 35165231 A Case of Potential Pharmacokinetic Kratom-drug Interactions Resulting in Toxicity and Subsequent Treatment of Kratom Use Disorder With Buprenorphine/Naloxone. 2022 Feb 14 1
2 35380747 The negative impact of vitamin D on antipsychotic drug exposure may counteract its potential benefits in schizophrenia. 2022 Jul 1
3 34204223 Severe Adverse Drug Reactions to Quetiapine in Two Patients Carrying CYP2D6*4 Variants: A Case Report. 2021 Jun 17 2
4 34440433 Genetic Variations Associated with Long-Term Treatment Response in Bipolar Depression. 2021 Aug 18 1
5 34683865 Variants in COMT, CYP3A5, CYP2B6, and ABCG2 Alter Quetiapine Pharmacokinetics. 2021 Sep 28 2
6 32276526 Cytochrome P450 (CYP450) Interactions Involving Atypical Antipsychotics are Common in Community-Dwelling Older Adults Treated for Behavioral and Psychological Symptoms of Dementia. 2020 Apr 8 1
7 32446424 High Doses of Drugs Extensively Metabolized by CYP3A4 Were Needed to Reach Therapeutic Concentrations in Two Patients Taking Inducers. 2020 Apr - Jun 1
8 32910451 [Carbamazepine and quetiapine: a neglected, but highly relevant interaction]. 2020 1
9 33199804 New insights into quetiapine metabolism using molecular networking. 2020 Nov 16 2
10 29702137 Reduced clearance of venlafaxine in a combined treatment with quetiapine. 2018 Jul 13 1
11 28340451 The role of drug-drug interactions in prostate cancer treatment: Focus on abiraterone acetate/prednisone and enzalutamide. 2017 Apr 1
12 28585378 4β-Hydroxycholesterol level significantly correlates with steady-state serum concentration of the CYP3A4 substrate quetiapine in psychiatric patients. 2017 Nov 2
13 29369597 How long does the pharmacokinetic interaction between carbamazepine and quetiapine last after carbamazepine withdrawal? 2017 Dec 1
14 25868121 The Influence of the CYP3A4*22 Polymorphism and CYP2D6 Polymorphisms on Serum Concentrations of Aripiprazole, Haloperidol, Pimozide, and Risperidone in Psychiatric Patients. 2015 Jun 2
15 24092799 Priapism induced by boceprevir-CYP3A4 inhibition and α-adrenergic blockade: case report. 2014 Jan 1
16 24240480 Influence of ABCB1 and CYP3A5 genetic polymorphisms on the pharmacokinetics of quetiapine in healthy volunteers. 2014 Jan 1
17 24525658 The influence of the CYP3A4*22 polymorphism on serum concentration of quetiapine in psychiatric patients. 2014 Apr 5
18 24797229 Development of physiologically based pharmacokinetic model to evaluate the relative systemic exposure to quetiapine after administration of IR and XR formulations to adults, children and adolescents. 2014 Sep 3
19 23230007 Use of high doses of quetiapine in bipolar disorder episodes are not linked to high activity of cytochrome P4503A4 and/or cytochrome P4502D6. 2013 Sep 3
20 21903893 Investigation of a possible interaction between quetiapine and armodafinil in patients with schizophrenia: an open-label, multiple-dose study. 2012 Sep 1
21 21383647 Pharmacokinetic variability of quetiapine and the active metabolite N-desalkylquetiapine in psychiatric patients. 2011 Apr 2
22 22066308 Quetiapine. A me-too neuroleptic; no panacea. 2011 Nov 1
23 19022943 Metabolism of quetiapine by CYP3A4 and CYP3A5 in presence or absence of cytochrome B5. 2009 Feb 7
24 18537577 Metabolism of atypical antipsychotics: involvement of cytochrome p450 enzymes and relevance for drug-drug interactions. 2008 Jun 1
25 17214606 Metabolic drug interactions with newer antipsychotics: a comparative review. 2007 Jan 1
26 16390352 Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics. 2006 Jan 3
27 16841513 In vitro studies on quetiapine metabolism using the substrate depletion approach with focus on drug-drug interactions. 2006 2
28 15834460 Metabolic mechanism of quetiapine in vivo with clinical therapeutic dose. 2005 Mar 2
29 15883149 The dosing of atypical antipsychotics. 2005 May-Jun 2
30 15516294 A liquid chromatographic-electrospray-tandem mass spectrometric method for quantitation of quetiapine in human plasma and liver microsomes: application to study in vitro metabolism. 2004 Sep 1
31 15570533 [Risk of QTc prolongation due to combination of ziprasidone and quetiapine]. 2004 Nov 1
32 12670127 Interactions between the cytochrome P450 system and the second-generation antipsychotics. 2003 Mar 1
33 12186270 New antipsychotic agents for schizophrenia: pharmacokinetics and metabolism update. 2002 Jul 1
34 10843459 Biotransformation of post-clozapine antipsychotics: pharmacological implications. 2000 May 1
35 10917381 Hyperventilation associated with quetiapine. 2000 Mar 1
36 11051217 Quetiapine: a review of its safety in the management of schizophrenia. 2000 Oct 2
37 10422890 Drug metabolism and atypical antipsychotics. 1999 Jun 1