Hydrocortisone

⇄

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







90 Article(s)
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51 16675933 Cortisol and growth hormone: clinical implications of a complex, dynamic relationship. 2006 Apr 1
52 16842393 Poor correlation between 6beta-hydroxycortisol:cortisol molar ratios and midazolam clearance as measure of hepatic CYP3A activity. 2006 Aug 3
53 17364054 Some mutations of exon-7 in cytochrome P450 gene 3A4 and their effect on 6beta-hydroxylation of cortisol. 2006 Jun 2
54 15650881 Ile118Val genetic polymorphism of CYP3A4 and its effects on lipid-lowering efficacy of simvastatin in Chinese hyperlipidemic patients. 2005 Feb 1
55 15657405 Randomized pharmacokinetic and pharmacodynamic study of docetaxel: dosing based on body-surface area compared with individualized dosing based on cytochrome P450 activity estimated using a urinary metabolite of exogenous cortisol. 2005 Feb 20 1
56 15770075 Influence of itraconazole co-administration and CYP2D6 genotype on the pharmacokinetics of the new antipsychotic ARIPIPRAZOLE. 2005 Feb 1
57 16183337 Simultaneous determination of 6beta-hydroxycortisol and cortisol in human urine and plasma by liquid chromatography with ultraviolet absorbance detection for phenotyping the CYP3A activity. 2005 Nov 5 1
58 16261523 Effects of St John's wort (Hypericum perforatum L.) extract on plasma androgen concentrations in healthy men and women: a pilot study. 2005 Oct 2
59 14605865 Effect of rifampicin on the pharmacokinetics of imatinib mesylate (Gleevec, STI571) in healthy subjects. 2004 Feb 1
60 14715379 Within-person variability of urinary 6beta-hydroxycortisol to urinaryl ratios in Caucasian women. 2004 Jan 3
61 14751784 Simultaneous determination of 6beta-hydroxycortisol and cortisol in human urine by liquid chromatography with ultraviolet absorbance detection for phenotyping the CYP3A activity determined by the cortisol 6beta-hydroxylation clearance. 2004 Mar 5 1
62 15016124 The variability of liver graft function and urinary 6beta-hydroxycortisol to cortisol ratio during liver regeneration in liver transplant recipients. 2004 Apr 3
63 15025748 Effect of St John's wort on the activities of CYP1A2, CYP3A4, CYP2D6, N-acetyltransferase 2, and xanthine oxidase in healthy males and females. 2004 Apr 1
64 15266218 In vitro interaction of the HIV protease inhibitor ritonavir with herbal constituents: changes in P-gp and CYP3A4 activity. 2004 Jul-Aug 1
65 15545313 Interindividual and intraindividual variability of the urinary 6beta-Hydroxycortisol/Cortisol ratio in Chinese subjects: implications of its use for evaluating CYP3A activity. 2004 Dec 1
66 14570755 Evidence for the validity of cortisol 6 beta-hydroxylation clearance as a new index for in vivo cytochrome P450 3A phenotyping in humans. 2003 Nov 3
67 12167569 Glucocorticoid-mediated induction of CYP3A4 is decreased by disruption of a protein: DNA interaction distinct from the pregnane X receptor response element. 2002 Sep 1
68 12451288 A wide interindividual variability of urinary 6beta-hydroxycortisol to free cortisol in 487 healthy Japanese subjects in near basal condition. 2002 Dec 1
69 11160617 Modulation of P450 CYP3A4-dependent metabolism by P-glycoprotein: implications for P450 phenotyping. 2001 Feb 1
70 11181494 Novel mutations of CYP3A4 in Chinese. 2001 Mar 1
71 11303593 Epidemiological study of urinary 6beta-hydroxycortisol to cortisol ratios and breast cancer risk. 2001 Mar 2
72 11522047 Influence of amiodarone on urinary excretion of 6beta-hydroxycortisol in humans. 2001 1
73 11549205 No correlations between the urinary ratio of 6beta-hydroxycortisol to free cortisol and pharmacokinetics of alprazolam. 2001 Jul 1
74 10611140 Human hepatocytes in primary culture predict lack of cytochrome P-450 3A4 induction by eletriptan in vivo. 2000 Jan 1
75 10772626 Regulation of the CYP3A4 gene by hydrocortisone and xenobiotics: role of the glucocorticoid and pregnane X receptors. 2000 May 4
76 10805065 Circadian variation of the urinary 6beta-hydroxycortisol to cortisol ratio that would reflect hepatic CYP3A activity. 2000 Feb-Mar 2
77 10829051 Correlation between docetaxel clearance and estimated cytochrome P450 activity by urinary metabolite of exogenous cortisol. 2000 Jun 3
78 10073736 Comparison of urinary 6beta-hydroxycortisol/cortisol ratio between neonates and their mothers. 1999 Jan 1
79 10354961 Differences in the urinary excretion of 6-beta-hydroxycortisol/cortisol between Asian and Caucasian women. 1999 Jun 2
80 9492385 Modification of paclitaxel metabolism in a cancer patient by induction of cytochrome P450 3A4. 1998 Mar 2
81 9753209 Effect of troglitazone on urinary excretion of 6beta-hydroxycortisol. 1998 Sep 1
82 9855326 Cytochrome P450 3A4 activity in premenopausal and postmenopausal women, based on 6-beta-hydroxycortisol:cortisol ratios. 1998 Nov-Dec 3
83 8608525 Urinary 6 beta-hydroxycortisol excretion in Hong Kong Chinese patients with hepatocellular carcinoma and other chronic liver diseases. 1996 Apr 15 1
84 8700118 Bimodal distribution of renal cytochrome P450 3A activity in humans. 1996 Jul 1
85 7858720 Simultaneous determination of urinary free cortisol and 6 beta-hydroxycortisol by high-performance liquid chromatography to measure human CYP3A activity. 1994 Oct 3 1
86 8265621 Human cytochrome P450 3A4: enzymatic properties of a purified recombinant fusion protein containing NADPH-P450 reductase. 1993 Dec 15 1
87 8349787 Identification of the fetal liver cytochrome CYP3A7 in human endometrium and placenta. 1993 Aug 1
88 1302569 Urinary 6 beta-hydroxycortisol/cortisol ratios measured by high-performance liquid chromatography for use as a biomarker for the human cytochrome P-450 3A4. 1992 Nov-Dec 4
89 1454750 Absence of CYP3A genetic polymorphism assessed by urinary excretion of 6 beta-hydroxycortisol in 102 healthy subjects on rifampicin. 1992 Oct 1
90 1732074 Heterogeneity of CYP3A isoforms metabolizing erythromycin and cortisol. 1992 Jan 3