Hydrocortisone

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







90 Article(s)
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1 35589097 Simultaneous Determination of Cortisol and 6β-Hydroxycortisol in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry. 2022 May 20 2
2 33622083 Using the CYP3A Activity Evaluation to Predict the Efficacy and Safety of Diazepam in Patients With Alcohol Withdrawal Syndrome. 2021 Feb 24 1
3 33897064 Impact of the Omics-Based Biomarkers on the Fluvoxamine's Steady-State Concentration, Efficacy and Safety in Patients with Affective Disorders Comorbid with Alcohol Use Disorder. 2021 Jan 12 2
4 34092821 Impact of the Omics-Based Biomarkers on the Mirtazapine's Steady-State Concentration, Efficacy and Safety in Patients with Affective Disorders Comorbid with Alcohol Use Disorder. 2021 Mar 16 2
5 34390638 MicroRNAs as novel biomarkers for rivaroxaban therapeutic drug monitoring. 2021 Aug 13 1
6 34633961 [Adrenal crisis associated with modafinil use]. 2021 2
7 34664787 Studies on CYP3A activity during the menstrual cycle as measured by urinary 6β-hydroxycortisol/cortisol. 2021 Dec 3
8 34880651 MicroRNAs as Novel Biomarkers for P2Y12 - Inhibitors Resistance Prediction. 2021 1
9 34881490 Dried blood spots analysis of 6β-hydroxycortisol and cortisol using liquid chromatography/tandem mass spectrometry for calculating 6β-hydroxycortisol to cortisol ratio. 2021 Dec 1
10 31608377 Heritability of Cortisol Production and Metabolism Throughout Adolescence. 2020 Feb 1 1
11 31721244 A novel random forest integrative approach based on endogenous CYP3A4 phenotype for predicting tacrolimus concentrations and dosages in Chinese renal transplant patients. 2020 Apr 1
12 32001245 Comparison of steroid hormone hydroxylation mediated by cytochrome P450 3A subfamilies. 2020 Mar 30 2
13 32112986 Effects of plasma concentration of micro-RNA Mir-27b and CYP3A4*22 on equilibrium concentration of alprazolam in patients with anxiety disorders comorbid with alcohol use disorder. 2020 May 20 4
14 32656158 Development and validation of a method for the simultaneous quantification of endogenous steroids metabolized by CYP3A. 2020 Jun 1
15 30683357 Assessment of electrocatalytic hydroxylase activity of cytochrome P450 3A4 (CYP3A4) by means of derivatization of 6β-hydroxycortisol by sulfuric acid for fluorimetric assay. 2019 May 1 1
16 30919109 Mechanisms of CYP3A Induction During Pregnancy: Studies in HepaRG Cells. 2019 Mar 27 6
17 31102151 Genotyping and phenotyping CYP3A4\CYP3A5: no association with antiplatelet effect of clopidogrel. 2019 Aug 1
18 31339834 Comparison of Steroid Hormone Hydroxylations by and Docking to Human Cytochromes P450 3A4 and 3A5. 2019 3
19 31581123 Adrenal insufficiency, be aware of drug interactions! 2019 Oct 3 1
20 31603853 The influence of taurine and L-carnitine on 6 β-hydroxycortisol/cortisol ratio in human urine of healthy volunteers. 2019 Oct 11 6
21 29343979 The influence of CYP3A5 polymorphisms on haloperidol treatment in patients with alcohol addiction. 2018 1
22 29606886 Influence of ABCB1 and CYP3A5 gene polymorphisms on pharmacokinetics of apixaban in patients with atrial fibrillation and acute stroke. 2018 1
23 29780235 The cytochrome P450 isoenzyme and some new opportunities for the prediction of negative drug interaction in vivo. 2018 1
24 30607725 A New Method for Quantitative Determination of Steroid Metabolites of Cytochrome P450-Dependent Reactions Using Fluorescent Spectroscopy. 2018 Nov 4
25 28157069 Delayed de-induction of CYP2C9 compared to CYP3A after discontinuation of rifampicin: Report of two cases
. 2017 May 1
26 28787271 Genotyping and phenotyping of CYP2D6 and CYP3A isoenzymes in patients with alcohol use disorder: correlation with haloperidol plasma concentration. 2017 Sep 26 1
27 29075133 Do CYP2C19 and ABCB1 gene polymorphisms and low CYP3A4 isoenzyme activity have an impact on stent implantation complications in acute coronary syndrome patients? 2017 2
28 26924289 Prediction of tacrolimus metabolism and dosage requirements based on CYP3A4 phenotype and CYP3A5(*)3 genotype in Chinese renal transplant recipients. 2016 Apr 1
29 27317471 Urinary 6β-Hydroxycortisol/Cortisol Ratio Most Highly Correlates With Midazolam Clearance Under Hepatic CYP3A Inhibition and Induction in Females: A Pharmacometabolomics Approach. 2016 Sep 4
30 27511886 Associations of the CYP3A5*3 and CYP3A4*1G polymorphisms with the pharmacokinetics of oral midazolam and the urinary 6β-hydroxycortisol/cortisol ratio as markers of CYP3A activity in healthy male Chinese. 2016 Oct 1
31 25407158 Alteration in cytochrome P450 3A4 activity as measured by a urine cortisol assay in HIV-1-infected pregnant women and relationship to antiretroviral pharmacokinetics. 2015 Mar 1
32 25678418 Regioselective hydroxylation of steroid hormones by human cytochromes P450. 2015 May 1
33 26639694 CYP3A4 activity and haloperidol effects in alcohol addicts. 2015 2
34 24468605 Effect of ethosuximide on cortisol metabolism in the treatment of congenital adrenal hyperplasia. 2014 May 1
35 24611975 The ratio of 6β-hydroxycortisol to cortisol in urine as a measure of cytochrome P450 3A activity in postmortem cases. 2014 Jul 1
36 23162091 Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement. 2013 Jan 3
37 23223499 Induction of hepatic CYP3A enzymes by pregnancy-related hormones: studies in human hepatocytes and hepatic cell lines. 2013 Feb 4
38 23404385 Association between urinary 6β-hydroxycortisol/cortisol ratio and CYP3A5 genotypes in a normotensive population. 2013 Feb 1
39 22120734 Identification of pharmacogenetic predictors of lipid-lowering response to atorvastatin in Chilean subjects with hypercholesterolemia. 2012 Feb 18 1
40 22253426 Expression and regulation of human fetal-specific CYP3A7 in mice. 2012 Mar 1
41 22741198 [Study on phenotypical activity of isoenzyme CYP3A4 in children]. 2012 1
42 21114969 Genotypes and phenotypes of CYP3A in Bangladeshi population. 2011 Mar 18 1
43 21490593 Evaluation of 6β-hydroxycortisol, 6β-hydroxycortisone, and a combination of the two as endogenous probes for inhibition of CYP3A4 in vivo. 2011 Jun 1
44 19959402 Quantification of cortisol and 6 beta-hydroxycortisol in human urine by LC-MS/MS, and gender-specific evaluation of the metabolic ratio as biomarker of CYP3A activity. 2010 Jan 1 2
45 20515961 Oxcarbazepine accelerates cortisol elimination via cytochrome P450 3A4 induction. 2010 Dec 2
46 19621007 A Holy Grail of clinical pharmacology: prediction of drug pharmacokinetics and pharmacodynamics in the individual patient. 2009 Aug 1
47 19701237 Evaluation of CYP3A activity in humans using three different parameters based on endogenous cortisol metabolism. 2009 Sep 1
48 19690646 Study of the Urinary Ratio of 6 beta-Hydroxycortisol/Cortisol as a Biomarker of CYP3A4 Activity in Egyptian Patients with Chronic Liver Diseases. 2007 Feb 7 1
49 16433874 Pharmacokinetics of ruboxistaurin are significantly altered by rifampicin-mediated CYP3A4 induction. 2006 Feb 1
50 16454691 Cytochrome P450 and anticancer drugs. 2006 Jan 1