| 201 |
10647906 | Isoform selective inhibition and inactivation of human cytochrome P450s by methylenedioxyphenyl compounds. | 1999 Dec |
1 |
| 202 |
20654528 | Improved Determination of Drug Metabolism by Perifusion of Recombinant V79 Cells Carrying Human CYP3A4. | 1999 Aug-Oct |
1 |
| 203 |
9531515 | Development of a non-high pressure liquid chromatography assay to determine testosterone hydroxylase (CYP3A) activity in human liver microsomes. | 1998 Apr |
1 |
| 204 |
9616193 | N-Dealkylation and hydroxylation of ebastine by human liver cytochrome P450. | 1998 Jun |
1 |
| 205 |
9719084 | Modification of clinical presentation of prostate tumors by a novel genetic variant in CYP3A4. | 1998 Aug 19 |
1 |
| 206 |
9732391 | A study on the metabolism of etoposide and possible interactions with antitumor or supporting agents by human liver microsomes. | 1998 Sep |
1 |
| 207 |
9806945 | Comparative studies of in vitro inhibition of cytochrome P450 3A4-dependent testosterone 6beta-hydroxylation by roxithromycin and its metabolites, troleandomycin, and erythromycin. | 1998 Nov |
2 |
| 208 |
9820175 | Potent and non-specific inhibition of cytochrome P450 by JM216, a new oral platinum agent. | 1998 Nov |
1 |
| 209 |
10022752 | Human cytochrome P450 3A (CYP3A) mediated midazolam metabolism: the effect of assay conditions and regioselective stimulation by alpha-naphthoflavone, terfenadine and testosterone. | 1998 Apr |
4 |
| 210 |
10660343 | Characterization of an allelic variant in the nifedipine-specific element of CYP3A4: ethnic distribution and implications for prostate cancer risk. Mutations in brief no. 191. Online. | 1998 |
1 |
| 211 |
14577225 | Thin-layer chromatographic analysis of human CYP3A-catalyzed testosterone 6 beta-hydroxylation. | 1998 |
1 |
| 212 |
9023313 | Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation. | 1997 Feb |
1 |
| 213 |
9107550 | Human cytochrome P450 3A4-catalyzed testosterone 6 beta-hydroxylation and erythromycin N-demethylation. Competition during catalysis. | 1997 Apr |
2 |
| 214 |
9152594 | Metabolism of phencyclidine by human liver microsomes. | 1997 May |
2 |
| 215 |
9157990 | Enhanced cyclophosphamide and ifosfamide activation in primary human hepatocyte cultures: response to cytochrome P-450 inducers and autoinduction by oxazaphosphorines. | 1997 May 15 |
1 |
| 216 |
9186495 | Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions. | 1997 Jun 15 |
1 |
| 217 |
9193880 | Inhibitory anti-peptide antibody against human CYP3A4. | 1997 Jun |
2 |
| 218 |
9249858 | Characterization of the P450 system in Göttingen minipigs. | 1997 |
1 |
| 219 |
9266706 | Expression of CYP3A in the human liver--evidence that the shift between CYP3A7 and CYP3A4 occurs immediately after birth. | 1997 Jul 15 |
1 |
| 220 |
9278209 | Differential inhibition of cytochrome P450 isoforms by the protease inhibitors, ritonavir, saquinavir and indinavir. | 1997 Aug |
1 |
| 221 |
9298257 | Applications of primary human hepatocytes in the evaluation of pharmacokinetic drug-drug interactions: evaluation of model drugs terfenadine and rifampin. | 1997 Jul |
1 |
| 222 |
9402952 | Pig hepatocytes as an in vitro model to study the regulation of human CYP3A4: prediction of drug-drug interactions with 17 alpha-ethynylestradiol. | 1997 Nov 6 |
1 |
| 223 |
9485522 | Metabolism of epinastine, a histamine H1 receptor antagonist, in human liver microsomes in comparison with that of terfenadine. | 1997 Dec |
1 |
| 224 |
9486958 | HIV protease inhibitors, saquinavir, indinavir and ritonavir: inhibition of CYP3A4-mediated metabolism of testosterone and benzoxazinorifamycin, KRM-1648, in human liver microsomes. | 1997 Dec |
1 |
| 225 |
21781753 | Isolation of a bovine full length cytochrome P450 (CYP3A) cDNA sequence and its functional expression in V79 cells. | 1997 Feb 15 |
1 |
| 226 |
8548776 | Metabolism of docetaxel by human cytochromes P450: interactions with paclitaxel and other antineoplastic drugs. | 1996 Jan 1 |
2 |
| 227 |
8561495 | Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes. | 1996 Jan 15 |
1 |
| 228 |
8619853 | High rates of substrate hydroxylation by human cytochrome P450 3A4 in reconstituted membranous vesicles: influence of membrane charge. | 1996 Apr 16 |
1 |
| 229 |
8781778 | Comparative studies of drug-metabolizing enzymes in dog, monkey, and human small intestines, and in Caco-2 cells. | 1996 Jun |
1 |
| 230 |
8806738 | Stable expression of human cytochrome P450 3A4 in conjunction with human NADPH-cytochrome P450 oxidoreductase in V79 Chinese hamster cells. | 1996 Aug 15 |
1 |
| 231 |
8817061 | The use of transgenic cell lines for evaluating toxic metabolites of carbamazepine. | 1996 Jun |
1 |
| 232 |
8866826 | Multiple forms of human P450 expressed in Saccharomyces cerevisiae. Systematic characterization and comparison with those of the rat. | 1996 Apr 26 |
1 |
| 233 |
8956327 | Development of Caco-2 cells expressing high levels of cDNA-derived cytochrome P4503A4. | 1996 Nov |
1 |
| 234 |
8959645 | Effects of erythromycin and roxithromycin on oxidation of testosterone and nifedipine catalyzed by CYP3A4 in human liver microsomes. | 1996 Nov |
1 |
| 235 |
8968357 | Identification of human cytochrome P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450. | 1996 Dec |
1 |
| 236 |
7575636 | Tiamulin inhibits human CYP3A4 activity in an NIH/3T3 cell line stably expressing CYP3A4 cDNA. | 1995 Sep 7 |
1 |
| 237 |
7587944 | Metabolism of terfenadine associated with CYP3A(4) activity in human hepatic microsomes. | 1995 Jun |
1 |
| 238 |
7628296 | Human liver cytochrome P4503A biotransformation of the cyclosporin derivative SDZ IMM 125. | 1995 Mar |
1 |
| 239 |
7720517 | Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver. | 1995 Jan |
1 |
| 240 |
7720520 | Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes. | 1995 Jan |
1 |
| 241 |
7833826 | Modulation of cytochrome P450 activities by 7,8-benzoflavone and its metabolites. | 1994 Oct |
1 |
| 242 |
7903909 | Taxol metabolism by human liver microsomes: identification of cytochrome P450 isozymes involved in its biotransformation. | 1994 Jan 15 |
1 |
| 243 |
8265621 | Human cytochrome P450 3A4: enzymatic properties of a purified recombinant fusion protein containing NADPH-P450 reductase. | 1993 Dec 15 |
1 |
| 244 |
8424894 | The role of cytochrome P450 3A (CYP3A) isoform(s) in oxidative metabolism of testosterone and benzphetamine in human adult and fetal liver. | 1993 Jan |
5 |