146 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
51 | 24292054 | Prediction of in vivo carbamazepine 10,11-epoxidation from in vitro metabolic studies with human liver microsomes: importance of its sigmoidal kinetics. | 2013 | 1 |
52 | 24382036 | [Pulmonary embolism due to interaction between rivaroxaban and carbamazepine]. | 2013 | 1 |
53 | 21996064 | Histone deacetylase 1 is required for Carbamazepine-induced CYP3A4 expression. | 2012 Jan 25 | 7 |
54 | 22197672 | Prediction of sites of metabolism in a substrate molecule, instanced by carbamazepine oxidation by CYP3A4. | 2012 Jan 15 | 2 |
55 | 21190921 | Therapeutic effects of ciprofloxacin on the pharmacokinetics of carbamazepine in healthy adult male volunteers. | 2011 Jan | 2 |
56 | 21294720 | Cellular localization and functional significance of CYP3A4 in the human epileptic brain. | 2011 Mar | 2 |
57 | 21441468 | Simulation of clinical drug-drug interactions from hepatocyte CYP3A4 induction data and its potential utility in trial designs. | 2011 Jul | 1 |
58 | 21832258 | Luciferin IPA-based higher throughput human hepatocyte screening assays for CYP3A4 inhibition and induction. | 2011 Sep | 1 |
59 | 21992114 | The structural basis for homotropic and heterotropic cooperativity of midazolam metabolism by human cytochrome P450 3A4. | 2011 Dec 20 | 2 |
60 | 20369030 | Clinical pharmacokinetic interactions between antiepileptic drugs and hormonal contraceptives. | 2010 Mar 1 | 1 |
61 | 20699409 | A 96-well plate assay for CYP4503A induction using cryopreserved human hepatocytes. | 2010 Nov | 1 |
62 | 20847137 | CYP3A4*16 and CYP3A4*18 alleles found in East Asians exhibit differential catalytic activities for seven CYP3A4 substrate drugs. | 2010 Dec | 4 |
63 | 19006545 | 4beta-hydroxycholesterol as an endogenous marker for CYP3A4/5 activity. Stability and half-life of elimination after induction with rifampicin. | 2009 Jan | 1 |
64 | 19182847 | Carbamazepine and falsely positive screening tests for Cushing's syndrome. | 2009 Jan 23 | 1 |
65 | 19255940 | Functional characterization of CYP3A4.16: catalytic activities toward midazolam and carbamazepine. | 2009 Feb | 1 |
66 | 19451401 | Evaluation of luciferin-isopropyl acetal as a CYP3A4 substrate for human hepatocytes: effects of organic solvents, cytochrome P450 (P450) inhibitors, and P450 inducers. | 2009 Aug | 1 |
67 | 19744012 | Effect of CYP3A5*3 genotype on serum carbamazepine concentrations at steady-state in Korean epileptic patients. | 2009 Oct | 2 |
68 | 17971810 | Pharmacodynamics of carbamazepine-mediated induction of CYP3A4, CYP1A2, and Pgp as assessed by probe substrates midazolam, caffeine, and digoxin. | 2008 Jul | 2 |
69 | 18096676 | CYP3A4-Mediated carbamazepine (CBZ) metabolism: formation of a covalent CBZ-CYP3A4 adduct and alteration of the enzyme kinetic profile. | 2008 Mar | 12 |
70 | 18279471 | Time course of the increase in 4beta-hydroxycholesterol concentration during carbamazepine treatment of paediatric patients with epilepsy. | 2008 May | 2 |
71 | 18372180 | An epoxidation mechanism of carbamazepine by CYP3A4. | 2008 May 1 | 5 |
72 | 18420779 | Comparative analysis of CYP3A heteroactivation by steroid hormones and flavonoids in different in vitro systems and potential in vivo implications. | 2008 Jul | 1 |
73 | 18463198 | Pathways of carbamazepine bioactivation in vitro. III. The role of human cytochrome P450 enzymes in the formation of 2,3-dihydroxycarbamazepine. | 2008 Aug | 4 |
74 | 18781906 | Influence of enzyme-inducing antiepileptic drugs on trough level of imatinib in glioblastoma patients. | 2008 Sep | 1 |
75 | 18783297 | General framework for the prediction of oral drug interactions caused by CYP3A4 induction from in vivo information. | 2008 | 2 |
76 | 17346248 | A comparative pharmacokinetic study in healthy volunteers of the effect of carbamazepine and oxcarbazepine on cyp3a4. | 2007 Mar | 4 |
77 | 17374625 | Does metronidazole interact with CYP3A substrates by inhibiting their metabolism through this metabolic pathway? Or should other mechanisms be considered? | 2007 Apr | 1 |
78 | 17502775 | Pharmacokinetics of aripiprazole and concomitant carbamazepine. | 2007 Jun | 1 |
79 | 17541885 | Effects of comedication on the serum levels of aripiprazole: evidence from a routine therapeutic drug monitoring service. | 2007 May | 1 |
80 | 18033049 | [Carbamazepine and clarithromycin: a clinically relevant drug interaction]. | 2007 Nov | 1 |
81 | 16390352 | Effects of cytochrome P450 3A modulators ketoconazole and carbamazepine on quetiapine pharmacokinetics. | 2006 Jan | 1 |
82 | 16600452 | Effect of carbamazepine on the single oral dose pharmacokinetics of perospirone and its active metabolite. | 2006 Sep 30 | 1 |
83 | 16720703 | Carbamazepine toxicity induced by lopinavir/ritonavir and nelfinavir. | 2006 Jun | 1 |
84 | 17190925 | Optimizing therapy of seizures in women who use oral contraceptives. | 2006 Dec 26 | 1 |
85 | 15572649 | Predictive models of CYP3A4 Heteroactivation: in vitro-in vivo scaling and pharmacophore modeling. | 2005 Mar | 2 |
86 | 15673597 | Effects of pomegranate juice on human cytochrome p450 3A (CYP3A) and carbamazepine pharmacokinetics in rats. | 2005 May | 3 |
87 | 15708356 | Novel pathways of bile acid metabolism involving CYP3A4. | 2005 Feb 21 | 1 |
88 | 15747502 | Autoantibodies against CYP2D6 and other drug-metabolizing enzymes in autoimmune hepatitis type 2. | 2005 | 1 |
89 | 15829439 | Study of urinary 6 beta-hydroxycortisol/cortisol ratio in spot urine sample as a biomarker of 3A4 enzyme activity in healthy and epileptic subjects of Egyptian population. | 2005 Jun | 2 |
90 | 16135660 | Pathways of carbamazepine bioactivation in vitro: II. The role of human cytochrome P450 enzymes in the formation of 2-hydroxyiminostilbene. | 2005 Dec | 2 |
91 | 16318439 | Clinical use of carbamazepine for bipolar disorders. | 2005 Dec | 1 |
92 | 15024831 | [A case of polymyalgia rheumatica with improved steroid-responsibility after discontinuing carbamazepine]. | 2004 Jan | 1 |
93 | 15298747 | Urinary 6beta-hydroxycortisol/17-hydroxycorticosteroids ratio as a measure of hepatic CYP3A4 capacity after enzyme induction. | 2004 Jul | 1 |
94 | 15371980 | Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans. | 2004 Sep | 1 |
95 | 15383492 | Evidence of significant contribution from CYP3A5 to hepatic drug metabolism. | 2004 Dec | 1 |
96 | 15519127 | Carbamazepine pharmacokinetics are not affected by zonisamide: in vitro mechanistic study and in vivo clinical study in epileptic patients. | 2004 Nov | 2 |
97 | 12606595 | In vivo CYP3A4 heteroactivation is a possible mechanism for the drug interaction between felbamate and carbamazepine. | 2003 Jun | 8 |
98 | 12642469 | CYP3A4 and CYP3A7-mediated carbamazepine 10,11-epoxidation are activated by differential endogenous steroids. | 2003 Apr | 2 |
99 | 12673034 | Induction of CYP3As in HepG2 cells by several drugs. Association between induction of CYP3A4 and expression of glucocorticoid receptor. | 2003 Apr | 3 |
100 | 14512885 | Sex is a major determinant of CYP3A4 expression in human liver. | 2003 Oct | 1 |