Verapamil

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







69 Article(s)
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Pub. Year
#Total Relationships
51 14512885 Sex is a major determinant of CYP3A4 expression in human liver. 2003 Oct 1
52 11907487 Shed human enterocytes as a tool for the study of expression and function of intestinal drug-metabolizing enzymes and transporters. 2002 Mar 1
53 12036391 How important are gender differences in pharmacokinetics? 2002 1
54 12130727 Piperine, a major constituent of black pepper, inhibits human P-glycoprotein and CYP3A4. 2002 Aug 1
55 11318771 Carbamazepine is not a substrate for P-glycoprotein. 2001 Apr 2
56 11422004 Inhibitory effects of verapamil and diltiazem on simvastatin metabolism in human liver microsomes. 2001 May 2
57 11724091 Compound cardiac toxicity of oral erythromycin and verapamil. 2001 Nov 2
58 10640508 Drug interactions with calcium channel blockers: possible involvement of metabolite-intermediate complexation with CYP3A. 2000 Feb 5
59 10859149 Verapamil metabolite exposure in older and younger men during steady-state oral verapamil administration. 2000 Jul 1
60 11038161 Automated definition of the enzymology of drug oxidation by the major human drug metabolizing cytochrome P450s. 2000 Nov 1
61 11498403 Does P-glycoprotein play a role in anticancer drug pharmacokinetics? 2000 Dec 2
62 10417494 The effect of ketoconazole on the jejunal permeability and CYP3A metabolism of (R/S)-verapamil in humans. 1999 Aug 1
63 11741214 Comparative studies to determine the selective inhibitors for P-glycoprotein and cytochrome P4503A4. 1999 2
64 9663178 Effects of verapamil and diltiazem on the pharmacokinetics and pharmacodynamics of buspirone. 1998 Jun 1
65 9400033 Characterization of interintestinal and intraintestinal variations in human CYP3A-dependent metabolism. 1997 Dec 1
66 10837554 Enzyme-catalyzed processes of first-pass hepatic and intestinal drug extraction. 1997 Sep 15 1
67 8861661 Dextromethorphan as an in vivo probe for the simultaneous determination of CYP2D6 and CYP3A activity. 1996 Mar 29 1
68 8232610 Identification of P450 enzymes involved in metabolism of verapamil in humans. 1993 Sep 1
69 8423765 Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites. 1993 Jan 4