Ketoconazole

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







524 Article(s)
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501 8667235 The biotransformation of clomipramine in vitro, identification of the cytochrome P450s responsible for the separate metabolic pathways. 1996 Jun 1
502 8723736 The aliphatic oxidation of salmeterol to alpha-hydroxysalmeterol in human liver microsomes is catalyzed by CYP3A. 1996 May 1
503 8786569 Theophylline metabolism in human liver microsomes: inhibition studies. 1996 Mar 2
504 8799527 Enzyme kinetic modelling as a tool to analyse the behaviour of cytochrome P450 catalysed reactions: application to amitriptyline N-demethylation. 1996 Jun 2
505 8801060 Significance of metabolism in the disposition and action of the antidysrhythmic drug, dofetilide. In vitro studies and correlation with in vivo data. 1996 Apr 1
506 8820421 Role of cytochrome P450 3A4 in human metabolism of MK-639, a potent human immunodeficiency virus protease inhibitor. 1996 Mar 2
507 8866916 In vitro interaction of the antipsychotic agent olanzapine with human cytochromes P450 CYP2C9, CYP2C19, CYP2D6 and CYP3A. 1996 Mar 1
508 8886601 Metabolism of fentanyl, a synthetic opioid analgesic, by human liver microsomes. Role of CYP3A4. 1996 Sep 1
509 8886602 Inhibition and kinetics of cytochrome P4503A activity in microsomes from rat, human, and cdna-expressed human cytochrome P450. 1996 Sep 1
510 8968357 Identification of human cytochrome P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450. 1996 Dec 1
511 7473143 N-demethylation of amitriptyline in vitro: role of cytochrome P-450 3A (CYP3A) isoforms and effect of metabolic inhibitors. 1995 Nov 1
512 7545582 A NIH/3T3 cell line stably expressing human cytochrome P450-3A4 used in combination with a lacZ' shuttle vector to study mutagenicity. 1995 May 26 1
513 7587944 Metabolism of terfenadine associated with CYP3A(4) activity in human hepatic microsomes. 1995 Jun 1
514 7587966 In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P4503A4 and NADPH-P450 reductase. Comparison to human liver microsomes and precision-cut liver tissue slices. 1995 Jul 1
515 7628296 Human liver cytochrome P4503A biotransformation of the cyclosporin derivative SDZ IMM 125. 1995 Mar 1
516 7720517 Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver. 1995 Jan 1
517 7736913 Biotransformation of losartan to its active carboxylic acid metabolite in human liver microsomes. Role of cytochrome P4502C and 3A subfamily members. 1995 Feb 1
518 8531125 Potent and selective inactivation of human liver microsomal cytochrome P-450 isoforms by L-754,394, an investigational human immune deficiency virus protease inhibitor. 1995 Dec 2
519 8703658 N-Hydroxylation of dapsone by multiple enzymes of cytochrome P450: implications for inhibition of haemotoxicity. 1995 Dec 1
520 8846621 Metabolism of drugs by cytochrome P450 3A isoforms. Implications for drug interactions in psychopharmacology. 1995 1
521 9815997 Similarity of metabolism for CAI (NSC 609974) in human liver tissue in vitro and in humans in vivo 1995 Apr 1
522 7888294 Characterisation of the cytochrome P450 enzymes involved in the in vitro metabolism of granisetron. 1994 Dec 2
523 7937537 Inhibition of human CYP3A catalyzed 1'-hydroxy midazolam formation by ketoconazole, nifedipine, erythromycin, cimetidine, and nizatidine. 1994 Jun 1
524 7995001 Oral triazolam is potentially hazardous to patients receiving systemic antimycotics ketoconazole or itraconazole. 1994 Dec 1