Vitamin D

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







46 Article(s)
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#Total Relationships
1 35184385 Gene Expression Profiling of 1α,25(OH)2 D3 Treatment in 2D/3D Human Hepatocyte Models Reveals CYP3A4 Induction but Minor Changes in Other Xenobiotic-Metabolizing Genes. 2022 May 1
2 35380747 The negative impact of vitamin D on antipsychotic drug exposure may counteract its potential benefits in schizophrenia. 2022 Jul 3
3 35569070 Long-term efficacy and safety of rifampin in the treatment of a patient carrying a CYP24A1 loss-of-function variant. 2022 May 15 2
4 35625833 The Interplay between Vitamin D, Exposure of Anticholinergic Antipsychotics and Cognition in Schizophrenia. 2022 May 9 1
5 33920130 Vitamin D Deficiency in Older Patients-Problems of Sarcopenia, Drug Interactions, Management in Deficiency. 2021 Apr 10 1
6 34719640 Variation in Expression of Cytochrome P450 3A Isoforms and Toxicological Effects: Endo- and Exogenous Substances as Regulatory Factors and Substrates. 2021 1
7 32681429 Altered expression of cytochrome P450 enzymes involved in metabolism of androgens and vitamin D in the prostate as a risk factor for prostate cancer. 2020 Oct 1
8 32717896 Simulation of Physicochemical and Pharmacokinetic Properties of Vitamin D3 and Its Natural Derivatives. 2020 Jul 23 2
9 32867201 Tuning Adipogenic Differentiation in ADSCs by Metformin and Vitamin D: Involvement of miRNAs. 2020 Aug 27 1
10 33330279 Vitamin D Status in Russian Children and Adolescents: Contribution of Genetic and Exogenous Factors. 2020 1
11 30058048 Drug-metabolizing enzymes CYP3A as a link between tacrolimus and vitamin D in renal transplant recipients: is it relevant in clinical practice? 2019 Jul 2
12 30205156 The serum vitamin D metabolome: What we know and what is still to discover. 2019 Feb 2
13 29153269 Vitamin D pathway gene polymorphisms influenced vitamin D level among pregnant women. 2018 Dec 1
14 29461981 CYP3A4 mutation causes vitamin D-dependent rickets type 3. 2018 May 1 6
15 30248338 Angiopoietin-Like Protein 8 Is a Novel Vitamin D Receptor Target Gene Involved in Nonalcoholic Fatty Liver Pathogenesis. 2018 Dec 1
16 28324001 CYP3A4 Induction by Rifampin: An Alternative Pathway for Vitamin D Inactivation in Patients With CYP24A1 Mutations. 2017 May 1 3
17 28418012 CYP3A4 is a crosslink between vitamin D and calcineurin inhibitors in solid organ transplant recipients: implications for bone health. 2017 Dec 3
18 28817905 Re: CYP3A4 Induction by Rifampin: An Alternative Pathway for Vitamin D Inactivation in Patients with CYP24A1 Mutations. 2017 Sep 1
19 26366751 Vitamin D Receptor-Mediated Upregulation of CYP3A4 and MDR1 by Quercetin in Caco-2 cells. 2016 Jan 1
20 26686945 Single nucleotide polymorphisms in the vitamin D pathway associating with circulating concentrations of vitamin D metabolites and non-skeletal health outcomes: Review of genetic association studies. 2016 Nov 1
21 26827958 Vitamin D in Prostate Cancer. 2016 1
22 26869438 Genetically Modified Caco-2 Cells With Improved Cytochrome P450 Metabolic Capacity. 2016 Feb 1
23 26970587 Hydroxylation of 20-hydroxyvitamin D3 by human CYP3A4. 2016 May 1
24 27022466 miRNA-27b levels are associated with CYP3A activity in vitro and in vivo. 2015 Dec 1
25 24486455 Ginsenoside-mediated blockade of 1α,25-dihydroxyvitamin D3 inactivation in human liver and intestine in vitro. 2014 May 1
26 24655660 Plasma levels of 25-hydroxyvitamin D3 and in vivo markers of cytochrome P450 3A activity in Swedes and Koreans: effects of a genetic polymorphism and oral contraceptives. 2014 Oct 1
27 22985909 Interplay between vitamin D and the drug metabolizing enzyme CYP3A4. 2013 Jul 3
28 23212742 Enhancement of hepatic 4-hydroxylation of 25-hydroxyvitamin D3 through CYP3A4 induction in vitro and in vivo: implications for drug-induced osteomalacia. 2013 May 1
29 23307906 Drug-vitamin D interactions: a systematic review of the literature. 2013 Apr 2
30 23965431 Effects of decreased vitamin D and accumulated uremic toxin on human CYP3A4 activity in patients with end-stage renal disease. 2013 Aug 19 1
31 22205755 An inducible cytochrome P450 3A4-dependent vitamin D catabolic pathway. 2012 Apr 2
32 22484315 Intestinal CYP3A4 and midazolam disposition in vivo associate with VDR polymorphisms and show seasonal variation. 2012 Jul 1 2
33 22903070 Vitamin D and drug-metabolising enzymes. 2012 Dec 1
34 22939842 Regulation of CYP3A4 and CYP3A5 expression and modulation of "intracrine" metabolism of androgens in prostate cells by liganded vitamin D receptor. 2012 Nov 25 3
35 21349923 Seasonal variation in blood drug concentrations and a potential relationship to vitamin D. 2011 May 2
36 20153625 Curcumin: a novel nutritionally derived ligand of the vitamin D receptor with implications for colon cancer chemoprevention. 2010 Dec 1
37 19414624 Up-regulation of transporters and enzymes by the vitamin D receptor ligands, 1alpha,25-dihydroxyvitamin D3 and vitamin D analogs, in the Caco-2 cell monolayer. 2009 Aug 1
38 17965521 Rapid and drastic induction of CYP3A4 mRNA expression via vitamin D receptor in human intestinal LS180 cells. 2007 Oct 1
39 16344723 Genetic signature consistent with selection against the CYP3A4*1B allele in non-African populations. 2006 Jan 1
40 16691293 Steroid and xenobiotic receptor and vitamin D receptor crosstalk mediates CYP24 expression and drug-induced osteomalacia. 2006 Jun 1
41 15546903 CYP3A4 is a vitamin D-24- and 25-hydroxylase: analysis of structure function by site-directed mutagenesis. 2005 Feb 2
42 15578590 Molecular and functional comparison of 1,25-dihydroxyvitamin D(3) and the novel vitamin D receptor ligand, lithocholic acid, in activating transcription of cytochrome P450 3A4. 2005 Apr 1 1
43 11991950 Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes. 2002 Jul 12 1
44 12016314 Vitamin D receptor as an intestinal bile acid sensor. 2002 May 17 1
45 12470639 Liganded VDR induces CYP3A4 in small intestinal and colon cancer cells via DR3 and ER6 vitamin D responsive elements. 2002 Dec 20 1
46 11723248 Transcriptional control of intestinal cytochrome P-4503A by 1alpha,25-dihydroxy vitamin D3. 2001 Dec 1