| 1 |
32737897 | Drug-drug and drug-food interactions in an infant with early-onset SCN2A epilepsy treated with carbamazepine, phenytoin and a ketogenic diet. | 2021 Mar |
1 |
| 2 |
34495458 | Physiologically-Based Pharmacokinetic Modelling of Entrectinib Parent and Active Metabolite to Support Regulatory Decision-Making. | 2021 Nov |
1 |
| 3 |
32215663 | Refractory Bullous Pemphigoid Improved by Discontinuation of Phenytoin as an CYP3A4 Inducer. | 2020 Apr 6 |
1 |
| 4 |
32350061 | Enrichment-free High-throughput Liquid Chromatography-Multiple-Reaction Monitoring Quantification of Cytochrome P450 Proteins in Plated Human Hepatocytes Direct from 96-Well Plates Enables Routine Protein Induction Measurements. | 2020 Jul |
1 |
| 5 |
32446424 | High Doses of Drugs Extensively Metabolized by CYP3A4 Were Needed to Reach Therapeutic Concentrations in Two Patients Taking Inducers. | 2020 Apr - Jun |
1 |
| 6 |
29199506 | Inadequate response to imatinib treatment in chronic myeloid leukemia due to a drug interaction with phenytoin. | 2019 Apr |
1 |
| 7 |
29649093 | Comparison of CYP3A4-Inducing Capacity of Enzyme-Inducing Antiepileptic Drugs Using 4β-Hydroxycholesterol as Biomarker. | 2018 Aug |
4 |
| 8 |
30155396 | Important drug interaction involving phenytoin and quetiapine. | 2018 Jul |
1 |
| 9 |
30581412 | Pharmacokinetic Interactions of Clinical Interest Between Direct Oral Anticoagulants and Antiepileptic Drugs. | 2018 |
1 |
| 10 |
28875044 | Decreased Rivaroxaban Levels in a Patient with Cerebral Vein Thrombosis Receiving Phenytoin. | 2017 |
1 |
| 11 |
27450623 | Interactions between non-vitamin K oral anticoagulants and antiepileptic drugs. | 2016 Oct |
1 |
| 12 |
27713827 | Evaluation of a novel PXR-knockout in HepaRG™ cells. | 2016 Oct |
1 |
| 13 |
27794414 | Drug interaction between erlotinib and phenytoin for brain metastases in a patient with nonsmall cell lung cancer. | 2016 Nov |
1 |
| 14 |
26312962 | Decreased responsiveness to oxycodone: A case of a pharmacokinetic drug interaction? | 2015 Jul-Aug |
1 |
| 15 |
26516577 | Applicability of second-generation upcyte® human hepatocytes for use in CYP inhibition and induction studies. | 2015 Oct |
1 |
| 16 |
21635243 | Effects of lamotrigine and phenytoin on the pharmacokinetics of atorvastatin in healthy volunteers. | 2011 Jul |
1 |
| 17 |
21832258 | Luciferin IPA-based higher throughput human hepatocyte screening assays for CYP3A4 inhibition and induction. | 2011 Sep |
1 |
| 18 |
20369030 | Clinical pharmacokinetic interactions between antiepileptic drugs and hormonal contraceptives. | 2010 Mar 1 |
1 |
| 19 |
19202563 | Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes. | 2009 Jan-Feb |
1 |
| 20 |
19451401 | Evaluation of luciferin-isopropyl acetal as a CYP3A4 substrate for human hepatocytes: effects of organic solvents, cytochrome P450 (P450) inhibitors, and P450 inducers. | 2009 Aug |
1 |
| 21 |
19694743 | Gefitinib-phenytoin interaction is not correlated with the C-erythromycin breath test in healthy male volunteers. | 2009 Aug |
3 |
| 22 |
18076219 | Interaction profile of armodafinil with medications metabolized by cytochrome P450 enzymes 1A2, 3A4 and 2C19 in healthy subjects. | 2008 |
1 |
| 23 |
18332078 | Comparison of immortalized Fa2N-4 cells and human hepatocytes as in vitro models for cytochrome P450 induction. | 2008 Jun |
1 |
| 24 |
18473749 | Drugs behave as substrates, inhibitors and inducers of human cytochrome P450 3A4. | 2008 May |
1 |
| 25 |
18783297 | General framework for the prediction of oral drug interactions caused by CYP3A4 induction from in vivo information. | 2008 |
2 |
| 26 |
17190925 | Optimizing therapy of seizures in women who use oral contraceptives. | 2006 Dec 26 |
1 |
| 27 |
17233196 | Lipid lowering inefficacy of high-dose statin therapy due to concurrent use of phenytoin. | 2006 Dec |
1 |
| 28 |
15747502 | Autoantibodies against CYP2D6 and other drug-metabolizing enzymes in autoimmune hepatitis type 2. | 2005 |
1 |
| 29 |
15983905 | A potentially significant interaction between efavirenz and phenytoin: a case report and review of the literature. | 2005 Jul 15 |
1 |
| 30 |
16205037 | [Drug-drug interaction of antifungal drugs]. | 2005 Oct |
1 |
| 31 |
14977870 | Regulation of CYP2B6 in primary human hepatocytes by prototypical inducers. | 2004 Mar |
2 |
| 32 |
15247556 | Coadministration of lopinavir/ritonavir and phenytoin results in two-way drug interaction through cytochrome P-450 induction. | 2004 Aug 15 |
3 |
| 33 |
12673034 | Induction of CYP3As in HepG2 cells by several drugs. Association between induction of CYP3A4 and expression of glucocorticoid receptor. | 2003 Apr |
3 |
| 34 |
12708941 | Phenytoin-diazepam interaction. | 2003 May |
3 |
| 35 |
14522368 | The role of chemotherapy in brain metastases. | 2003 Oct |
1 |
| 36 |
14616412 | Coadministration of voriconazole and phenytoin: pharmacokinetic interaction, safety, and toleration. | 2003 Dec |
1 |
| 37 |
12242602 | Concomitant use of mirtazapine and phenytoin: a drug-drug interaction study in healthy male subjects. | 2002 Sep |
1 |
| 38 |
12405865 | Interindividual variability of the clinical pharmacokinetics of methadone: implications for the treatment of opioid dependence. | 2002 |
1 |
| 39 |
12505310 | Receptor-dependent regulation of the CYP3A4 gene. | 2002 Dec 27 |
1 |
| 40 |
11158730 | Inhibition of cytochrome P450 (CYP450) isoforms by isoniazid: potent inhibition of CYP2C19 and CYP3A. | 2001 Feb |
1 |
| 41 |
10678302 | Phenytoin as a possible cause of acetaminophen hepatotoxicity: case report and review of the literature. | 2000 Feb |
1 |
| 42 |
11038165 | Formation of a dihydroxy metabolite of phenytoin in human liver microsomes/cytosol: roles of cytochromes P450 2C9, 2C19, and 3A4. | 2000 Nov |
1 |
| 43 |
10219967 | A reporter gene assay to assess the molecular mechanisms of xenobiotic-dependent induction of the human CYP3A4 gene in vitro. | 1999 Mar |
2 |
| 44 |
10486655 | [A new cause of resistant arterial hypertension: coprescription with anticonvulsant treatments]. | 1999 Aug |
1 |
| 45 |
9533108 | Induction of tirilazad clearance by phenytoin. | 1998 Mar |
1 |
| 46 |
9753209 | Effect of troglitazone on urinary excretion of 6beta-hydroxycortisol. | 1998 Sep |
1 |
| 47 |
9010637 | Identification of cytochromes P450 involved in the human liver microsomal metabolism of the thromboxane A2 inhibitor seratrodast (ABT-001). | 1997 Jan |
1 |
| 48 |
9084959 | Protease inhibitors in patients with HIV disease. Clinically important pharmacokinetic considerations. | 1997 Mar |
1 |
| 49 |
9159561 | Concentrations and effects of zopiclone are greatly reduced by rifampicin. | 1997 May |
1 |
| 50 |
9314612 | Pharmacokinetic interactions with felbamate. In vitro-in vivo correlation. | 1997 Sep |
1 |