| 1 |
35589097 | Simultaneous Determination of Cortisol and 6β-Hydroxycortisol in Human Plasma by Liquid Chromatography-Tandem Mass Spectrometry. | 2022 May 20 |
1 |
| 2 |
33622083 | Using the CYP3A Activity Evaluation to Predict the Efficacy and Safety of Diazepam in Patients With Alcohol Withdrawal Syndrome. | 2021 Feb 24 |
2 |
| 3 |
34390638 | MicroRNAs as novel biomarkers for rivaroxaban therapeutic drug monitoring. | 2021 Aug 13 |
1 |
| 4 |
34664787 | Studies on CYP3A activity during the menstrual cycle as measured by urinary 6β-hydroxycortisol/cortisol. | 2021 Dec |
3 |
| 5 |
34880651 | MicroRNAs as Novel Biomarkers for P2Y12 - Inhibitors Resistance Prediction. | 2021 |
1 |
| 6 |
31721244 | A novel random forest integrative approach based on endogenous CYP3A4 phenotype for predicting tacrolimus concentrations and dosages in Chinese renal transplant patients. | 2020 Apr |
1 |
| 7 |
32112986 | Effects of plasma concentration of micro-RNA Mir-27b and CYP3A4*22 on equilibrium concentration of alprazolam in patients with anxiety disorders comorbid with alcohol use disorder. | 2020 May 20 |
2 |
| 8 |
30683357 | Assessment of electrocatalytic hydroxylase activity of cytochrome P450 3A4 (CYP3A4) by means of derivatization of 6β-hydroxycortisol by sulfuric acid for fluorimetric assay. | 2019 May 1 |
2 |
| 9 |
31102151 | Genotyping and phenotyping CYP3A4\CYP3A5: no association with antiplatelet effect of clopidogrel. | 2019 Aug |
1 |
| 10 |
29343979 | The influence of CYP3A5 polymorphisms on haloperidol treatment in patients with alcohol addiction. | 2018 |
1 |
| 11 |
29606886 | Influence of ABCB1 and CYP3A5 gene polymorphisms on pharmacokinetics of apixaban in patients with atrial fibrillation and acute stroke. | 2018 |
1 |
| 12 |
29780235 | The cytochrome P450 isoenzyme and some new opportunities for the prediction of negative drug interaction in vivo. | 2018 |
1 |
| 13 |
30607725 | A New Method for Quantitative Determination of Steroid Metabolites of Cytochrome P450-Dependent Reactions Using Fluorescent Spectroscopy. | 2018 Nov |
1 |
| 14 |
28157069 | Delayed de-induction of CYP2C9 compared to CYP3A after discontinuation of rifampicin: Report of two cases
. | 2017 May |
1 |
| 15 |
28787271 | Genotyping and phenotyping of CYP2D6 and CYP3A isoenzymes in patients with alcohol use disorder: correlation with haloperidol plasma concentration. | 2017 Sep 26 |
1 |
| 16 |
29075133 | Do CYP2C19 and ABCB1 gene polymorphisms and low CYP3A4 isoenzyme activity have an impact on stent implantation complications in acute coronary syndrome patients? | 2017 |
2 |
| 17 |
26399557 | Relationships between Endogenous Plasma Biomarkers of Constitutive Cytochrome P450 3A Activity and Single-Time-Point Oral Midazolam Microdose Phenotype in Healthy Subjects. | 2016 Apr |
3 |
| 18 |
26924289 | Prediction of tacrolimus metabolism and dosage requirements based on CYP3A4 phenotype and CYP3A5(*)3 genotype in Chinese renal transplant recipients. | 2016 Apr |
1 |
| 19 |
27317471 | Urinary 6β-Hydroxycortisol/Cortisol Ratio Most Highly Correlates With Midazolam Clearance Under Hepatic CYP3A Inhibition and Induction in Females: A Pharmacometabolomics Approach. | 2016 Sep |
4 |
| 20 |
25407158 | Alteration in cytochrome P450 3A4 activity as measured by a urine cortisol assay in HIV-1-infected pregnant women and relationship to antiretroviral pharmacokinetics. | 2015 Mar |
1 |
| 21 |
26150050 | Evaluation of 6β-Hydroxycortisol and 6β-Hydroxycortisone as Biomarkers for Cytochrome P450 3A Activity: Insight into Their Predictive Value for Estimating Oral Immunosuppressant Metabolism. | 2015 Oct |
3 |
| 22 |
26639694 | CYP3A4 activity and haloperidol effects in alcohol addicts. | 2015 |
2 |
| 23 |
26819743 | Serum concentrations of clarithromycin and rifampicin in pulmonary Mycobacterium avium complex disease: long-term changes due to drug interactions and their association with clinical outcomes. | 2015 |
1 |
| 24 |
24611975 | The ratio of 6β-hydroxycortisol to cortisol in urine as a measure of cytochrome P450 3A activity in postmortem cases. | 2014 Jul |
1 |
| 25 |
23073666 | Effect of the fluoroquinolone antibacterial agent DX-619 on the apparent formation and renal clearances of 6β-hydroxycortisol, an endogenous probe for CYP3A4 inhibition, in healthy subjects. | 2013 Feb |
1 |
| 26 |
23162091 | Mitotane therapy in adrenocortical cancer induces CYP3A4 and inhibits 5α-reductase, explaining the need for personalized glucocorticoid and androgen replacement. | 2013 Jan |
1 |
| 27 |
23404385 | Association between urinary 6β-hydroxycortisol/cortisol ratio and CYP3A5 genotypes in a normotensive population. | 2013 Feb |
1 |
| 28 |
23674608 | Comparison of endogenous 4β-hydroxycholesterol with midazolam as markers for CYP3A4 induction by rifampicin. | 2013 Aug |
1 |
| 29 |
22120734 | Identification of pharmacogenetic predictors of lipid-lowering response to atorvastatin in Chilean subjects with hypercholesterolemia. | 2012 Feb 18 |
1 |
| 30 |
22741198 | [Study on phenotypical activity of isoenzyme CYP3A4 in children]. | 2012 |
1 |
| 31 |
21490593 | Evaluation of 6β-hydroxycortisol, 6β-hydroxycortisone, and a combination of the two as endogenous probes for inhibition of CYP3A4 in vivo. | 2011 Jun |
3 |
| 32 |
19959402 | Quantification of cortisol and 6 beta-hydroxycortisol in human urine by LC-MS/MS, and gender-specific evaluation of the metabolic ratio as biomarker of CYP3A activity. | 2010 Jan 1 |
1 |
| 33 |
17371531 | Effect of honey on CYP3A4, CYP2D6 and CYP2C19 enzyme activity in healthy human volunteers. | 2007 Apr |
1 |
| 34 |
19690646 | Study of the Urinary Ratio of 6 beta-Hydroxycortisol/Cortisol as a Biomarker of CYP3A4 Activity in Egyptian Patients with Chronic Liver Diseases. | 2007 Feb 7 |
2 |
| 35 |
16433874 | Pharmacokinetics of ruboxistaurin are significantly altered by rifampicin-mediated CYP3A4 induction. | 2006 Feb |
1 |
| 36 |
16842393 | Poor correlation between 6beta-hydroxycortisol:cortisol molar ratios and midazolam clearance as measure of hepatic CYP3A activity. | 2006 Aug |
2 |
| 37 |
15657405 | Randomized pharmacokinetic and pharmacodynamic study of docetaxel: dosing based on body-surface area compared with individualized dosing based on cytochrome P450 activity estimated using a urinary metabolite of exogenous cortisol. | 2005 Feb 20 |
1 |
| 38 |
15726657 | No relevant effect of ursodeoxycholic acid on cytochrome P450 3A metabolism in primary biliary cirrhosis. | 2005 Mar |
1 |
| 39 |
15770075 | Influence of itraconazole co-administration and CYP2D6 genotype on the pharmacokinetics of the new antipsychotic ARIPIPRAZOLE. | 2005 Feb |
1 |
| 40 |
16183337 | Simultaneous determination of 6beta-hydroxycortisol and cortisol in human urine and plasma by liquid chromatography with ultraviolet absorbance detection for phenotyping the CYP3A activity. | 2005 Nov 5 |
1 |
| 41 |
14605865 | Effect of rifampicin on the pharmacokinetics of imatinib mesylate (Gleevec, STI571) in healthy subjects. | 2004 Feb |
1 |
| 42 |
14715379 | Within-person variability of urinary 6beta-hydroxycortisol to urinaryl ratios in Caucasian women. | 2004 Jan |
3 |
| 43 |
14751784 | Simultaneous determination of 6beta-hydroxycortisol and cortisol in human urine by liquid chromatography with ultraviolet absorbance detection for phenotyping the CYP3A activity determined by the cortisol 6beta-hydroxylation clearance. | 2004 Mar 5 |
1 |
| 44 |
15016124 | The variability of liver graft function and urinary 6beta-hydroxycortisol to cortisol ratio during liver regeneration in liver transplant recipients. | 2004 Apr |
3 |
| 45 |
15298747 | Urinary 6beta-hydroxycortisol/17-hydroxycorticosteroids ratio as a measure of hepatic CYP3A4 capacity after enzyme induction. | 2004 Jul |
2 |
| 46 |
15365655 | Effects of growth hormone deficiency and rhGH replacement therapy on the 6beta-hydroxycortisol/free cortisol ratio, a marker of CYP3A activity, in growth hormone-deficient children. | 2004 Oct |
2 |
| 47 |
15373933 | Drug interaction between St John's Wort and quazepam. | 2004 Oct |
1 |
| 48 |
15545313 | Interindividual and intraindividual variability of the urinary 6beta-Hydroxycortisol/Cortisol ratio in Chinese subjects: implications of its use for evaluating CYP3A activity. | 2004 Dec |
1 |
| 49 |
12787801 | Reduced urinary 6beta-hydroxycortisol to cortisol ratios in patients with liver cirrhosis. | 2003 May |
2 |
| 50 |
14605790 | Urinary 6beta-hydroxycortisol: a validated test for evaluating drug induction or drug inhibition mediated through CYP3A in humans and in animals. | 2003 Dec |
1 |