Itraconazole

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cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







165 Article(s)
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101 15726880 Simultaneous itraconazole bioequivalence assessment and CYP3A phenotyping in South American subjects. 2005 Feb 1
102 15770075 Influence of itraconazole co-administration and CYP2D6 genotype on the pharmacokinetics of the new antipsychotic ARIPIPRAZOLE. 2005 Feb 4
103 15900215 Relative impact of CYP3A genotype and concomitant medication on the severity of atorvastatin-induced muscle damage. 2005 Jun 1
104 15905803 Clinical pharmacokinetic monitoring of itraconazole is warranted in only a subset of patients. 2005 Jun 2
105 15969931 Effect of micafungin on cytochrome P450 3A4 and multidrug resistance protein 1 activities, and its comparison with azole antifungal drugs. 2005 Jun 1
106 16012077 Identification of human cytochrome P450 enzymes involved in the formation of 4-hydroxyestazolam from estazolam. 2005 May 1
107 16042675 Coadministration of gemfibrozil and itraconazole has only a minor effect on the pharmacokinetics of the CYP2C9 and CYP3A4 substrate nateglinide. 2005 Aug 2
108 16122280 Clinical pharmacokinetics of telithromycin, the first ketolide antibacterial. 2005 1
109 16205037 [Drug-drug interaction of antifungal drugs]. 2005 Oct 3
110 16321618 Cytochrome P450 3A inhibitor itraconazole affects plasma concentrations of risperidone and 9-hydroxyrisperidone in schizophrenic patients. 2005 Nov 2
111 15133245 Identification of human p450 isoforms involved in the metabolism of the antiallergic drug, oxatomide, and its inhibitory effect on enzyme activity. 2004 May 2
112 15232663 Inhibition of the metabolism of etizolam by itraconazole in humans: evidence for the involvement of CYP3A4 in etizolam metabolism. 2004 Aug 2
113 15242978 Role of itraconazole metabolites in CYP3A4 inhibition. 2004 Oct 5
114 15289787 Effect of the CYP3A5 genotype on the pharmacokinetics of intravenous midazolam during inhibited and induced metabolic states. 2004 Aug 2
115 15447735 Effect of itraconazole on the pharmacokinetics of inhaled lidocaine. 2004 Sep 1
116 15521894 Effect of itraconazole on the pharmacokinetics and pharmacodynamics of a single oral dose of brotizolam. 2004 Nov 1
117 12619051 Effects of cysteine on the pharmacokinetics of itraconazole in rats with protein-calorie malnutrition. 2003 Mar 1
118 12709722 Effect of itraconazole on the pharmacokinetics of rosuvastatin. 2003 Apr 1
119 12883232 Effects of itraconazole on the plasma kinetics of quazepam and its two active metabolites after a single oral dose of the drug. 2003 Aug 1
120 12949438 Inhibition of cytochrome P450 3A: relevant drug interactions in gastroenterology. 2003 1
121 14517708 The effect of itraconazole on the pharmacokinetics and pharmacodynamics of bromazepam in healthy volunteers. 2003 Nov 1
122 12166560 Iatrogenic adrenal insufficiency as a side-effect of combined treatment of itraconazole and budesonide. 2002 Jul 1
123 12412882 Cushing's syndrome due to pharmacological interaction in a cystic fibrosis patient. 2002 1
124 11322176 Effect of clarithromycin and itraconazole on the pharmacokinetics of ropivacaine. 2001 Apr 1
125 11372588 Selegiline pharmacokinetics are unaffected by the CYP3A4 inhibitor itraconazole. 2001 Apr 1
126 11422002 Effect of itraconazole on the pharmacokinetics of prednisolone and methylprednisolone and cortisol secretion in healthy subjects. 2001 May 3
127 11465417 Inhibition of in vitro metabolism of simvastatin by itraconazole in humans and prediction of in vivo drug-drug interactions. 2001 May 1
128 11836874 [Safety profile of statins]. 2001 Nov 1
129 10668858 Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition. 2000 Jan 1
130 10709776 Effects of the antifungal agents on oxidative drug metabolism: clinical relevance. 2000 Feb 1
131 10731517 Differential inhibition of human CYP3A4 and Candida albicans CYP51 with azole antifungal agents. 2000 Mar 15 1
132 10853878 The effect of itraconazole on the pharmacokinetics and pharmacodynamics of oral prednisolone. 2000 Apr 1
133 10926350 Drug interactions with cisapride: clinical implications. 2000 Jul 1
134 11061579 Itraconazole alters the pharmacokinetics of atorvastatin to a greater extent than either cerivastatin or pravastatin. 2000 Oct 1
135 11103751 The cytochrome P450 3A4 inhibitor itraconazole markedly increases the plasma concentrations of dexamethasone and enhances its adrenal-suppressant effect. 2000 Nov 2
136 10027660 Effect of itraconazole on cerivastatin pharmacokinetics. 1999 Jan 1
137 10211916 Effects of itraconazole on the steady-state plasma concentrations of haloperidol and its reduced metabolite in schizophrenic patients: in vivo evidence of the involvement of CYP3A4 for haloperidol metabolism. 1999 Apr 1
138 10426160 Itraconazole decreases the clearance and enhances the effects of intravenously administered methylprednisolone in healthy volunteers. 1999 Jul 2
139 10449937 Safety of itraconazole in diabetic patients. 1999 1
140 10463320 Effects of itraconazole on the steady-state plasma concentrations of bromperidol and reduced bromperidol in schizophrenic patients. 1999 Jul 1
141 10600094 Potential interaction between itraconazole and clarithromycin. 1999 Dec 2
142 10730911 Drug interactions of the newer oral antifungal agents. 1999 Nov 1
143 9542477 Simvastatin but not pravastatin is very susceptible to interaction with the CYP3A4 inhibitor itraconazole. 1998 Mar 1
144 9551703 Fluconazole but not itraconazole decreases the metabolism of losartan to E-3174. 1998 Feb 1
145 9584328 Cytochrome P450 specificity of metabolism and interactions of oxybutynin in human liver microsomes. 1998 Apr 1
146 9626922 Effect of itraconazole on the pharmacokinetics and pharmacodynamics of zolpidem. 1998 Apr 1
147 9626923 Serum concentrations of clozapine and N-desmethylclozapine are unaffected by the potent CYP3A4 inhibitor itraconazole. 1998 Apr 1
148 9695720 Effect of itraconazole on the pharmacokinetics of atorvastatin. 1998 Jul 4
149 9726699 The CYP3A4 inhibitor intraconazole does not affect the pharmacokinetics of a new calcium-sensitizing drug levosimendan. 1998 Aug 1
150 9784084 Effect of itraconazole on the single oral dose pharmacokinetics and pharmacodynamics of alprazolam. 1998 Oct 2