| 1 |
32275771 | The Effects of Weak and Strong CYP3A Induction by Rifampicin on the Pharmacokinetics of Five Progestins and Ethinylestradiol Compared to Midazolam. | 2020 Oct |
2 |
| 2 |
27273461 | Pharmacokinetic Evaluation of CYP3A4-Mediated Drug-Drug Interactions of Isavuconazole With Rifampin, Ketoconazole, Midazolam, and Ethinyl Estradiol/Norethindrone in Healthy Adults. | 2017 Jan |
1 |
| 3 |
24997757 | Pharmacokinetic drug-drug interaction between ethinyl estradiol and gestodene, administered as a transdermal fertility control patch, and two CYP3A4 inhibitors and a CYP3A4 substrate. | 2015 Dec |
2 |
| 4 |
24161160 | Lack of an effect of rilpivirine on the pharmacokinetics of ethinylestradiol and norethindrone in healthy volunteers. | 2014 Feb |
1 |
| 5 |
24654690 | Click chemistry mediated Eu-tagging: activity-based specific quantification and simultaneous activity evaluation of CYP3A4 using 153Eu species-unspecific isotope dilution inductively coupled plasma mass spectrometry. | 2014 Apr 15 |
2 |
| 6 |
22809252 | 1,2,3-Triazole-heme interactions in cytochrome P450: functionally competent triazole-water-heme complexes. | 2012 Aug 14 |
2 |
| 7 |
19454483 | Further assessment of 17alpha-ethinyl estradiol as an inhibitor of different human cytochrome P450 forms in vitro. | 2009 Aug |
1 |
| 8 |
18294327 | Pharmacokinetics and tolerability of voriconazole and a combination oral contraceptive co-administered in healthy female subjects. | 2008 Apr |
1 |
| 9 |
17284510 | Absence of effect of oral rifaximin on the pharmacokinetics of ethinyl estradiol/norgestimate in healthy females. | 2007 Feb |
1 |
| 10 |
16837568 | Use of immortalized human hepatocytes to predict the magnitude of clinical drug-drug interactions caused by CYP3A4 induction. | 2006 Oct |
1 |
| 11 |
15764719 | Cytochrome P450 3A4 is the major enzyme responsible for the metabolism of laquinimod, a novel immunomodulator. | 2005 Jun |
1 |
| 12 |
16261523 | Effects of St John's wort (Hypericum perforatum L.) extract on plasma androgen concentrations in healthy men and women: a pilot study. | 2005 Oct |
2 |
| 13 |
15304426 | The involvement of CYP3A4 and CYP2C9 in the metabolism of 17 alpha-ethinylestradiol. | 2004 Nov |
1 |
| 14 |
15554232 | Rifampicin, a keystone inducer of drug metabolism: from Herbert Remmer's pioneering ideas to modern concepts. | 2004 Oct |
4 |
| 15 |
12537513 | Clinical pharmacokinetic profile of modafinil. | 2003 |
1 |
| 16 |
12817528 | Influence of drugs interacting with CYP3A4 on the pharmacokinetics, pharmacodynamics, and safety of the prandial glucose regulator repaglinide. | 2003 Jun |
1 |
| 17 |
14636322 | Dose-dependent induction of cytochrome P450 (CYP) 3A4 and activation of pregnane X receptor by topiramate. | 2003 Dec |
1 |
| 18 |
11849197 | The effects of an oral contraceptive containing ethinyloestradiol and norgestrel on CYP3A activity. | 2002 Jan |
2 |
| 19 |
11907170 | Mechanism-based inactivation of cytochrome P450 3A4 by 17 alpha-ethynylestradiol: evidence for heme destruction and covalent binding to protein. | 2002 Apr |
1 |
| 20 |
10898107 | Evaluation of the genetic component of variability in CYP3A4 activity: a repeated drug administration method. | 2000 Jul |
1 |
| 21 |
11012556 | Effect of an oral contraceptive preparation containing ethinylestradiol and gestodene on CYP3A4 activity as measured by midazolam 1'-hydroxylation. | 2000 Oct |
3 |
| 22 |
8613951 | Cytochrome P450-mediated metabolism of the HIV-1 protease inhibitor ritonavir (ABT-538) in human liver microsomes. | 1996 Apr |
1 |
| 23 |
8765473 | Identification of CYP3A4 as the principal enzyme catalyzing mifepristone (RU 486) oxidation in human liver microsomes. | 1996 Sep 13 |
2 |
| 24 |
7628296 | Human liver cytochrome P4503A biotransformation of the cyclosporin derivative SDZ IMM 125. | 1995 Mar |
1 |