| 1 |
34973473 | Pan-neuronal expression of human mutant huntingtin protein in Drosophila impairs immune response of hemocytes. | 2022 Feb 15 |
4 |
| 2 |
32941796 | Serine residues 13 and 16 are key modulators of mutant huntingtin induced toxicity in Drosophila. | 2021 Apr |
4 |
| 3 |
33772540 | Spinocerebellar Ataxia Type 1 protein Ataxin-1 is signaled to DNA damage by ataxia-telangiectasia mutated kinase. | 2021 May 17 |
1 |
| 4 |
34914364 | Polyglutamine-Specific Gold Nanoparticle Complex Alleviates Mutant Huntingtin-Induced Toxicity. | 2021 Dec 29 |
1 |
| 5 |
32967102 | Implications of the Orb2 Amyloid Structure in Huntington's Disease. | 2020 Sep 21 |
1 |
| 6 |
32975927 | Exploding the Repeat Length Paradigm while Exploring Amyloid Toxicity in Huntington's Disease. | 2020 Oct 20 |
1 |
| 7 |
30171891 | Mutational analysis implicates the amyloid fibril as the toxic entity in Huntington's disease. | 2018 Dec |
3 |
| 8 |
28235896 | Pathogenic Huntington Alters BMP Signaling and Synaptic Growth through Local Disruptions of Endosomal Compartments. | 2017 Mar 22 |
4 |
| 9 |
28871787 | NMR Spectroscopy-based Metabolomics of Drosophila Model of Huntington's Disease Suggests Altered Cell Energetics. | 2017 Oct 6 |
2 |
| 10 |
26728250 | Curcumin modulates cell death and is protective in Huntington's disease model. | 2016 Jan 5 |
6 |
| 11 |
26920069 | αB-Crystallin overexpression in astrocytes modulates the phenotype of the BACHD mouse model of Huntington's disease. | 2016 May 1 |
1 |
| 12 |
27309588 | Characterization of axonal transport defects in Drosophila Huntingtin mutants. | 2016 Sep - Dec |
4 |
| 13 |
27506601 | Altered lipid metabolism in Drosophila model of Huntington's disease. | 2016 Aug 10 |
4 |
| 14 |
25305076 | Comparative study of naturally occurring huntingtin fragments in Drosophila points to exon 1 as the most pathogenic species in Huntington's disease. | 2015 Feb 15 |
2 |
| 15 |
25761110 | Enhanced neuronal glucose transporter expression reveals metabolic choice in a HD Drosophila model. | 2015 |
1 |
| 16 |
25848931 | siRNA screen identifies QPCT as a druggable target for Huntington's disease. | 2015 May |
2 |
| 17 |
26942103 | Drosophila as a potential model to ameliorate mutant Huntington-mediated cardiac amyloidosis. | 2014 |
1 |
| 18 |
23555909 | Huntingtin's function in axonal transport is conserved in Drosophila melanogaster. | 2013 |
2 |
| 19 |
23652004 | A functional deficiency of TERA/VCP/p97 contributes to impaired DNA repair in multiple polyglutamine diseases. | 2013 |
1 |
| 20 |
23980182 | Huntington disease arises from a combinatory toxicity of polyglutamine and copper binding. | 2013 Sep 10 |
6 |
| 21 |
24022020 | Modeling Huntington disease in Drosophila: Insights into axonal transport defects and modifiers of toxicity. | 2013 Oct-Dec |
4 |
| 22 |
24367279 | Huntington's disease induced cardiac amyloidosis is reversed by modulating protein folding and oxidative stress pathways in the Drosophila heart. | 2013 |
5 |
| 23 |
21912091 | Pcaf modulates polyglutamine pathology in a Drosophila model of Huntington's disease. | 2012 |
1 |
| 24 |
22466800 | Rab11 rescues synaptic dysfunction and behavioural deficits in a Drosophila model of Huntington's disease. | 2012 Jul 1 |
2 |
| 25 |
22634544 | Drosophila eye color mutants as therapeutic tools for Huntington disease. | 2012 Apr-Jun |
2 |
| 26 |
22733771 | Axon injury and stress trigger a microtubule-based neuroprotective pathway. | 2012 Jul 17 |
2 |
| 27 |
22817726 | Choosing and using Drosophila models to characterize modifiers of Huntington's disease. | 2012 Aug |
4 |
| 28 |
21636279 | The kynurenine pathway modulates neurodegeneration in a Drosophila model of Huntington's disease. | 2011 Jun 7 |
2 |
| 29 |
21700213 | Neuronal store-operated calcium entry pathway as a novel therapeutic target for Huntington's disease treatment. | 2011 Jun 24 |
2 |
| 30 |
21909362 | High-content chemical and RNAi screens for suppressors of neurotoxicity in a Huntington's disease model. | 2011 |
1 |
| 31 |
22180703 | The biological function of the Huntingtin protein and its relevance to Huntington's Disease pathology. | 2011 Jan 1 |
1 |
| 32 |
20100940 | A genomewide RNA interference screen for modifiers of aggregates formation by mutant Huntingtin in Drosophila. | 2010 Apr |
3 |
| 33 |
20336775 | B2 attenuates polyglutamine-expanded androgen receptor toxicity in cell and fly models of spinal and bulbar muscular atrophy. | 2010 Aug 1 |
1 |
| 34 |
20399860 | Cystamine and intrabody co-treatment confers additional benefits in a fly model of Huntington's disease. | 2010 Oct |
2 |
| 35 |
20531388 | Mutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's disease. | 2010 Jul 21 |
2 |
| 36 |
21087194 | Selection of behaviors and segmental coordination during larval locomotion is disrupted by nuclear polyglutamine inclusions in a new Drosophila Huntington's disease-like model. | 2010 Dec |
1 |
| 37 |
19268537 | Live axonal transport disruption by mutant huntingtin fragments in Drosophila motor neuron axons. | 2009 May |
2 |
| 38 |
19380309 | Inactivation of Drosophila Huntingtin affects long-term adult functioning and the pathogenesis of a Huntington's disease model. | 2009 May-Jun |
2 |
| 39 |
18065778 | AKT-sensitive or insensitive pathways of toxicity in glial cells and neurons in Drosophila models of Huntington's disease. | 2008 Mar 15 |
2 |
| 40 |
18417352 | Expression of expanded polyglutamine targets profilin for degradation and alters actin dynamics. | 2008 Jun |
1 |
| 41 |
18423405 | ROCK and PRK-2 mediate the inhibitory effect of Y-27632 on polyglutamine aggregation. | 2008 May 28 |
2 |
| 42 |
18430781 | Rab5 modulates aggregation and toxicity of mutant huntingtin through macroautophagy in cell and fly models of Huntington disease. | 2008 May 15 |
2 |
| 43 |
17961788 | Interacting proteins as genetic modifiers of Huntington disease. | 2007 Nov |
1 |
| 44 |
16497721 | Rapamycin pre-treatment protects against apoptosis. | 2006 Apr 1 |
1 |
| 45 |
15590702 | Inactivation of Drosophila Apaf-1 related killer suppresses formation of polyglutamine aggregates and blocks polyglutamine pathogenesis. | 2005 Feb 1 |
1 |
| 46 |
15677486 | Expanded polyglutamine peptides disrupt EGF receptor signaling and glutamate transporter expression in Drosophila. | 2005 Mar 1 |
5 |
| 47 |
14978262 | Cytoplasmic aggregates trap polyglutamine-containing proteins and block axonal transport in a Drosophila model of Huntington's disease. | 2004 Mar 2 |
1 |
| 48 |
15064418 | SUMO modification of Huntingtin and Huntington's disease pathology. | 2004 Apr 2 |
1 |
| 49 |
12379151 | The predominantly HEAT-like motif structure of huntingtin and its association and coincident nuclear entry with dorsal, an NF-kB/Rel/dorsal family transcription factor. | 2002 Oct 14 |
1 |
| 50 |
11607033 | Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila. | 2001 Oct 18 |
1 |