Polyamines

adenosylmethionine decarboxylase 1 ; Homo sapiens







104 Article(s)
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1 33203990 AMD1 is required for the maintenance of leukemic stem cells and promotes chronic myeloid leukemic growth. 2021 Jan 2
2 34420674 The RATIOnal Role of Polyamines in Epidermal Differentiation. 2021 Sep 1
3 31140554 Polyamine synthesis enzyme AMD1 is closely associated with tumorigenesis and prognosis of human gastric cancers. 2020 Apr 22 1
4 31467246 A polyamine-independent role for S-adenosylmethionine decarboxylase. 2019 Sep 20 3
5 29342137 Corrigendum: mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer. 2018 Feb 22 1
6 29357564 Re: mTORC1-Dependent AMD1 Regulation Sustains Polyamine Metabolism in Prostate Cancer. 2018 Feb 1
7 29644784 MINDY1 Is a Downstream Target of the Polyamines and Promotes Embryonic Stem Cell Self-Renewal. 2018 Aug 1
8 29906410 Polyamine Regulator AMD1 Promotes Cell Migration in Epidermal Wound Healing. 2018 Dec 2
9 30138353 Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies. 2018 1
10 30323064 Roles of polyamines in translation. 2018 Nov 30 4
11 28642498 Uptake and metabolism of arginine impact Plasmodium development in the liver. 2017 Jun 22 1
12 28658205 mTORC1-dependent AMD1 regulation sustains polyamine metabolism in prostate cancer. 2017 Jul 6 1
13 29084986 In-silico gene essentiality analysis of polyamine biosynthesis reveals APRT as a potential target in cancer. 2017 Oct 30 2
14 27102990 Polyamine metabolism-based dual functional gene delivery system to synergistically inhibit the proliferation of cancer. 2016 Jun 15 5
15 25079701 Gene polymorphisms in the ornithine decarboxylase-polyamine pathway modify gastric cancer risk by interaction with isoflavone concentrations. 2015 Jul 2
16 26030749 Discovery of novel inhibitors of human S-adenosylmethionine decarboxylase based on in silico high-throughput screening and a non-radioactive enzymatic assay. 2015 Jun 1 2
17 24112028 Polyamines reprogram oxidative and nitrosative status and the proteome of citrus plants exposed to salinity stress. 2014 Apr 1
18 23041351 The nitric oxide donor sodium nitroprusside regulates polyamine and proline metabolism in leaves of Medicago truncatula plants. 2013 Mar 1
19 23260169 Effects of promoter methylation on increased expression of polyamine biosynthetic genes in suicide. 2013 Apr 1
20 22008221 Effects of histone modifications on increased expression of polyamine biosynthetic genes in suicide. 2012 Sep 1
21 22192816 Regulation and function of polyamines in African trypanosomes. 2012 Feb 2
22 22391449 AMD1 is essential for ESC self-renewal and is translationally down-regulated on differentiation to neural precursor cells. 2012 Mar 1 1
23 22722845 A tumour suppressor network relying on the polyamine-hypusine axis. 2012 Jul 12 2
24 23165208 A role for polyamine regulators in ESC self-renewal. 2012 Dec 15 2
25 21413019 Polyamines, androgens, and skeletal muscle hypertrophy. 2011 Jun 2
26 21827754 Molecular machines encoded by bacterially-derived multi-domain gene fusions that potentially synthesize, N-methylate and transfer long chain polyamines in diatoms. 2011 Sep 2 3
27 23573001 Biotic and abiotic stress tolerance in transgenic tomatoes by constitutive expression of S-adenosylmethionine decarboxylase gene. 2011 Apr 2
28 19997761 Structural biology of S-adenosylmethionine decarboxylase. 2010 Feb 2
29 20124698 Complexes of Thermotoga maritimaS-adenosylmethionine decarboxylase provide insights into substrate specificity. 2010 Feb 1
30 20514439 Characterization of Pt-, Pd-spermine complexes for their effect on polyamine pathway and cisplatin resistance in A2780 ovarian carcinoma cells. 2010 Jul 1
31 19209891 New insights into the design of inhibitors of human S-adenosylmethionine decarboxylase: studies of adenine C8 substitution in structural analogues of S-adenosylmethionine. 2009 Mar 12 2
32 19527050 Role of the sulfonium center in determining the ligand specificity of human s-adenosylmethionine decarboxylase. 2009 Jul 14 2
33 19584241 Inhibition of S-adenosylmethionine decarboxylase by inhibitor SAM486A connects polyamine metabolism with p53-Mdm2-Akt/protein kinase B regulation and apoptosis in neuroblastoma. 2009 Jul 7
34 20095967 Polyamine homoeostasis. 2009 Nov 4 2
35 18548481 Effects of antisense RNA targeting of ODC and AdoMetDC on the synthesis of polyamine synthesis and cell growth in prostate cancer cells using a prostatic androgen-dependent promoter in adenovirus. 2008 Sep 1 5
36 19053272 Structural basis for putrescine activation of human S-adenosylmethionine decarboxylase. 2008 Dec 16 2
37 19787085 Gene expression in Pre-MBT embryos and activation of maternally-inherited program of apoptosis to be executed at around MBT as a fail-safe mechanism in Xenopus early embryogenesis. 2008 May 29 2
38 17021820 Platinum drug effects on the expression of genes in the polyamine pathway: time-course and concentration-effect analysis based on Affymetrix gene expression profiling of A2780 ovarian carcinoma cells. 2007 May 1
39 17558447 Adenovirus-mediated expression of both antisense ornithine decarboxylase and S-adenosylmethionine decarboxylase inhibits lung cancer cell growth. 2007 Jun 3
40 17593800 Cloning, expression and purification of human S-adenosylmethionine decarboxylase gene alpha subunit. 2007 Feb 28 2
41 17676832 In silico chemical library screening and experimental validation of a novel 9-aminoacridine based lead-inhibitor of human S-adenosylmethionine decarboxylase. 2007 Sep-Oct 1
42 16257247 Novel properties of malarial S-adenosylmethionine decarboxylase as revealed by structural modelling. 2006 Jan 2
43 16490173 Adenovirus-mediated expression of both antisense ODC and AdoMetDC inhibited colorectal cancer cell growth in vitro. 2006 Mar 3
44 16515461 Structural basis for the inactivation of AdoMetDC K12R mutant. 2006 2
45 16783835 Polyamine depletion by ODC-AdoMetDC antisense adenovirus impairs human colorectal cancer growth and invasion in vitro and in vivo. 2006 Aug 4
46 16941339 Inhibition of multidrug-resistant HIV-1 by interference with cellular S-adenosylmethionine decarboxylase activity. 2006 Sep 15 2
47 15521072 HSG cells differentiated by culture on extracellular matrix involves induction of S-adenosylmethione decarboxylase and ornithine decarboxylase. 2005 May 2
48 15821146 The pivotal roles of the plant S-adenosylmethionine decarboxylase 5' untranslated leader sequence in regulation of gene expression at the transcriptional and posttranscriptional levels. 2005 May 2
49 15868382 Multi-centre Phase II trial of the polyamine synthesis inhibitor SAM486A (CGP48664) in patients with metastatic melanoma. 2005 Jun 1
50 16007177 Key role for p27Kip1, retinoblastoma protein Rb, and MYCN in polyamine inhibitor-induced G1 cell cycle arrest in MYCN-amplified human neuroblastoma cells. 2005 Aug 25 2