| 1 |
35499073 | Cross-species genetic screens identify transglutaminase 5 as a regulator of polyglutamine-expanded ataxin-1. | 2022 May 2 |
5 |
| 2 |
31381977 | 5'UTR-mediated regulation of Ataxin-1 expression. | 2020 Feb |
3 |
| 3 |
32005838 | Nuclear bodies formed by polyQ-ataxin-1 protein are liquid RNA/protein droplets with tunable dynamics. | 2020 Jan 31 |
2 |
| 4 |
32145456 | Nuclear inclusions of pathogenic ataxin-1 induce oxidative stress and perturb the protein synthesis machinery. | 2020 May |
6 |
| 5 |
32581673 | The Mechanisms of Nuclear Proteotoxicity in Polyglutamine Spinocerebellar Ataxias. | 2020 |
1 |
| 6 |
32581696 | Gene Deregulation and Underlying Mechanisms in Spinocerebellar Ataxias With Polyglutamine Expansion. | 2020 |
1 |
| 7 |
32671744 | Autophagy and Polyglutamine Disease. | 2020 |
1 |
| 8 |
32873576 | UTteR control through miRs: fine-tuning ATXN1 levels to prevent ataxia. | 2020 Sep 1 |
1 |
| 9 |
32954321 | ATXN1 repeat expansions confer risk for amyotrophic lateral sclerosis and contribute to TDP-43 mislocalization. | 2020 |
3 |
| 10 |
32962458 | Polyglutamine spinocerebellar ataxias: emerging therapeutic targets. | 2020 Nov |
2 |
| 11 |
32992839 | Dynamics of a Protein Interaction Network Associated to the Aggregation of polyQ-Expanded Ataxin-1. | 2020 Sep 25 |
1 |
| 12 |
30707359 | EvoPPI 1.0: a Web Platform for Within- and Between-Species Multiple Interactome Comparisons and Application to Nine PolyQ Proteins Determining Neurodegenerative Diseases. | 2019 Mar |
2 |
| 13 |
31655597 | ATXN1 N-terminal region explains the binding differences of wild-type and expanded forms. | 2019 Oct 26 |
8 |
| 14 |
29274668 | ATXN1 intermediate-length polyglutamine expansions are associated with amyotrophic lateral sclerosis. | 2018 Apr |
3 |
| 15 |
29533923 | Mutant ataxin1 disrupts cerebellar development in spinocerebellar ataxia type 1. | 2018 Jun 1 |
3 |
| 16 |
30108484 | PolyQ Tract Toxicity in SCA1 is Length Dependent in the Absence of CAG Repeat Interruption. | 2018 |
5 |
| 17 |
30473770 | Recent advances in understanding dominant spinocerebellar ataxias from clinical and genetic points of view. | 2018 |
2 |
| 18 |
27306906 | Mutant Ataxin-1 Inhibits Neural Progenitor Cell Proliferation in SCA1. | 2017 Apr |
4 |
| 19 |
29212253 | Ataxin-1 is involved in tumorigenesis of cervical cancer cells via the EGFR-RAS-MAPK signaling pathway. | 2017 Nov 7 |
2 |
| 20 |
26748090 | Impaired mTORC1-Dependent Expression of Homer-3 Influences SCA1 Pathophysiology. | 2016 Jan 6 |
1 |
| 21 |
26879337 | Characterization of the AXH domain of Ataxin-1 using enhanced sampling and functional mode analysis. | 2016 May |
1 |
| 22 |
27058144 | BIIB021, a synthetic Hsp90 inhibitor, induces mutant ataxin-1 degradation through the activation of heat shock factor 1. | 2016 Jul 7 |
12 |
| 23 |
27658206 | Polyglutamine Tract Expansion Increases S-Nitrosylation of Huntingtin and Ataxin-1. | 2016 |
1 |
| 24 |
27686464 | RNAi prevents and reverses phenotypes induced by mutant human ataxin-1. | 2016 Nov |
1 |
| 25 |
27895927 | Expansion, mosaicism and interruption: mechanisms of the CAG repeat mutation in spinocerebellar ataxia type 1. | 2016 |
7 |
| 26 |
25641559 | A key lysine residue in the AXH domain of ataxin-1 is essential for its ubiquitylation. | 2015 May |
4 |
| 27 |
27168726 | Stabilization and Degradation Mechanisms of Cytoplasmic Ataxin-1. | 2015 |
5 |
| 28 |
23853075 | Chemical shift assignment of the ataxin-1 AXH domain in complex with a CIC ligand peptide. | 2014 Oct |
1 |
| 29 |
24711972 | Mapping the self-association domains of ataxin-1: identification of novel non overlapping motifs. | 2014 |
1 |
| 30 |
24741770 | A review on the cause-effect relationship between oxidative stress and toxic proteins in the pathogenesis of neurodegenerative diseases. | 2014 Jan-Mar |
1 |
| 31 |
24858692 | Structural basis of the phosphorylation dependent complex formation of neurodegenerative disease protein Ataxin-1 and RBM17. | 2014 Jul 11 |
7 |
| 32 |
25131594 | Spontaneous self-assembly of pathogenic huntingtin exon 1 protein into amyloid structures. | 2014 |
6 |
| 33 |
25309920 | From pathways to targets: understanding the mechanisms behind polyglutamine disease. | 2014 |
1 |
| 34 |
23528090 | Self-assembly and conformational heterogeneity of the AXH domain of ataxin-1: an unusual example of a chameleon fold. | 2013 Mar 19 |
1 |
| 35 |
23754227 | Regulation of ataxin-1 phosphorylation and its impact on biology. | 2013 |
1 |
| 36 |
23760502 | An out-of-frame overlapping reading frame in the ataxin-1 coding sequence encodes a novel ataxin-1 interacting protein. | 2013 Jul 26 |
2 |
| 37 |
23877406 | New hope for therapy in neurodegenerative diseases. | 2013 Oct |
2 |
| 38 |
23935513 | The role of interruptions in polyQ in the pathology of SCA1. | 2013 |
2 |
| 39 |
24225362 | Clinical characteristics of patients with spinocerebellar ataxias 1, 2, 3 and 6 in the US; a prospective observational study. | 2013 Nov 13 |
1 |
| 40 |
21827903 | Spinocerebellar ataxia type 1. | 2012 |
2 |
| 41 |
21964520 | Comparative genetics of the poly-Q tract of ataxin-1 and its binding protein PQBP-1. | 2012 Apr |
1 |
| 42 |
22309224 | Spinocerebellar ataxia type 1 (SCA1): new pathoanatomical and clinico-pathological insights. | 2012 Dec |
2 |
| 43 |
22491195 | Factors influencing disease progression in autosomal dominant cerebellar ataxia and spastic paraplegia. | 2012 Apr |
1 |
| 44 |
22511762 | Ataxin-1 poly(Q)-induced proteotoxic stress and apoptosis are attenuated in neural cells by docosahexaenoic acid-derived neuroprotectin D1. | 2012 Jul 6 |
1 |
| 45 |
22531670 | SCA1-phosphorylation, a regulator of Ataxin-1 function and pathogenesis. | 2012 Dec |
8 |
| 46 |
22831947 | Inherited polyglutamine spinocerebellar ataxias in South Africa. | 2012 Jun 14 |
1 |
| 47 |
22916034 | Identification of human proteins that modify misfolding and proteotoxicity of pathogenic ataxin-1. | 2012 |
1 |
| 48 |
23022625 | Comparative aspects of polyglutamine binding domain in PQBP-1 among Vertebrata. | 2012 Dec 15 |
1 |
| 49 |
23197749 | Ataxin-1 and ataxin-2 intermediate-length PolyQ expansions in amyotrophic lateral sclerosis. | 2012 Dec 11 |
3 |
| 50 |
20451302 | Genome-wide analysis of miRNA expression reveals a potential role for miR-144 in brain aging and spinocerebellar ataxia pathogenesis. | 2011 Dec |
1 |