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35063734 | Niemann-Pick C1-Like 1 inhibitors for reducing cholesterol absorption. | 2022 Feb 15 |
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| 2 |
32368969 | Three Musketeers for Lowering Cholesterol: Statins, Ezetimibe and Evolocumab. | 2021 |
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| 3 |
32853776 | A prospective mechanism and source of cholesterol uptake by Plasmodium falciparum-infected erythrocytes co-cultured with HepG2 cells. | 2021 Feb |
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33760662 | NPC1L1-dependent transport of 27-alkyne cholesterol in intestinal epithelial cells. | 2021 May 1 |
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| 5 |
34067439 | Synthesis and Modeling of Ezetimibe Analogues. | 2021 May 22 |
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| 6 |
34272236 | Structural insights into the mechanism of human NPC1L1-mediated cholesterol uptake. | 2021 Jul |
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| 7 |
34407950 | Structures of dimeric human NPC1L1 provide insight into mechanisms for cholesterol absorption. | 2021 Aug |
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| 8 |
34511128 | Expression and prognostic significance of Niemann-Pick C1-Like 1 in colorectal cancer: a retrospective cohort study. | 2021 Sep 12 |
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| 9 |
31682937 | Inhibition of Niemann-Pick C1-like protein 1 by ezetimibe reduces uptake of deuterium-labeled vitamin D in mice. | 2020 Mar |
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| 10 |
32410728 | Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins. | 2020 May 15 |
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32596471 | Cryo-EM structures of NPC1L1 reveal mechanisms of cholesterol transport and ezetimibe inhibition. | 2020 Jun |
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| 12 |
32860884 | Ezetimibe impairs transcellular lipid trafficking and induces large lipid droplet formation in intestinal absorptive epithelial cells. | 2020 Dec |
2 |
| 13 |
30994973 | Nonglucuronidated Ezetimibe Disrupts CD13- and CD64-Coassembly in Membrane Microdomains and Decreases Cellular Cholesterol Content in Human Monocytes/Macrophages. | 2019 Aug |
2 |
| 14 |
31064810 | Hepatic Expression of Niemann-Pick C1-Like 1, a Cholesterol Reabsorber from Bile, Exacerbates Western Diet-Induced Atherosclerosis in LDL Receptor Mutant Mice. | 2019 Jul |
2 |
| 15 |
30391500 | Ezetimibe inhibits dengue virus infection in Huh-7 cells by blocking the cholesterol transporter Niemann-Pick C1-like 1 receptor. | 2018 Dec |
2 |
| 16 |
28057006 | Bisphenol A promotes cholesterol absorption in Caco-2 cells by up-regulation of NPC1L1 expression. | 2017 Jan 6 |
2 |
| 17 |
28167864 | Ezetimibe reduces cholesterol content and NF-kappaB activation in liver but not in intestinal tissue in guinea pigs. | 2017 |
2 |
| 18 |
28203044 | A case of sitosterolemia due to compound heterozygous mutations in ABCG5: clinical features and treatment outcomes obtained with colestimide and ezetimibe. | 2017 Jan |
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| 19 |
28315682 | N-terminal domain of the cholesterol transporter Niemann-Pick C1-like 1 (NPC1L1) is essential for α-tocopherol transport. | 2017 Apr 29 |
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| 20 |
28478831 | Hepatitis C virus may have an entero-hepatic cycle which could be blocked with ezetimibe. | 2017 May |
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| 21 |
29106532 | Using genetics to explore whether the cholesterol-lowering drug ezetimibe may cause an increased risk of cancer. | 2017 Dec 1 |
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| 22 |
26761771 | Characterization of the NPC1L1 gene and proteome from an exceptional responder to ezetimibe. | 2016 Mar |
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| 23 |
26923679 | Niemann-Pick C1-Like 1 (NPC1L1) Inhibition and Cardiovascular Diseases. | 2016 |
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| 24 |
26934923 | An Approach to Improve Intestinal Absorption of Poorly Absorbed Water-Insoluble Components via Niemann-Pick C1-Like 1. | 2016 |
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| 25 |
27714510 | Cardiovascular Risk Reduction in Patients with Nonalcoholic Fatty Liver Disease: The Potential Role of Ezetimibe. | 2016 Dec |
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| 26 |
25589339 | Efficacy of ezetimibe is not related to NPC1L1 gene polymorphisms in a pilot study of Chilean hypercholesterolemic subjects. | 2015 Feb |
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| 27 |
25841872 | Genetic variation in the cholesterol transporter NPC1L1, ischaemic vascular disease, and gallstone disease. | 2015 Jul 1 |
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| 28 |
26442834 | [Ezetimibe in clinical practice: from laboratory investigations to the IMPROVE-IT trial results]. | 2015 Jul-Aug |
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| 29 |
26492642 | Analysis of Niemann-Pick C1-like 1 (NPC1L1) genetic polymorphisms and haplotypes in Chinese Han population. | 2015 Sep |
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| 30 |
24214142 | Inhibition of Niemann-Pick-type C1-like1 by ezetimibe activates autophagy in human hepatocytes and reduces mutant α1-antitrypsin Z deposition. | 2014 Apr |
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| 31 |
24859282 | Luteolin and quercetin affect the cholesterol absorption mediated by epithelial cholesterol transporter niemann-pick c1-like 1 in caco-2 cells and rats. | 2014 |
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| 32 |
24861377 | Gene polymorphism and frequencies of the NPC1L1 gene (rs2072183, rs217434 and rs217428) in Japanese patients with dyslipidemia. | 2014 Oct |
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| 33 |
24906511 | Structure-activity relationship study of non-steroidal NPC1L1 ligands identified through cell-based assay using pharmacological chaperone effect as a readout. | 2014 Jul 15 |
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| 34 |
24974575 | The c.-133A > G polymorphism in NPC1L1 gene influences the efficacy of ezetimibe monotherapy on apolipoprotein A1 in hyperlipidemic patients. | 2014 Jun |
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25390462 | Inactivating mutations in NPC1L1 and protection from coronary heart disease. | 2014 Nov 27 |
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| 36 |
25551765 | Fomiroid A, a novel compound from the mushroom Fomitopsis nigra, inhibits NPC1L1-mediated cholesterol uptake via a mode of action distinct from that of ezetimibe. | 2014 |
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| 37 |
23830695 | Structure-activity relationship studies of Niemann-Pick type C1-like 1 (NPC1L1) ligands identified by screening assay monitoring pharmacological chaperone effect. | 2013 Sep 1 |
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| 38 |
23991401 | Intestinal and hepatic niemann-pick c1-like 1. | 2013 Aug |
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| 39 |
22007304 | The chylomicron: relationship to atherosclerosis. | 2012 |
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| 40 |
22579005 | Involvement of cholesterol membrane transporter Niemann-Pick C1-like 1 in the intestinal absorption of lutein. | 2012 |
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| 41 |
22785139 | Dietary cholesterol oxidation products accelerate plaque destabilization and rupture associated with monocyte infiltration/activation via the MCP-1-CCR2 pathway in mouse brachiocephalic arteries: therapeutic effects of ezetimibe. | 2012 |
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| 42 |
20809793 | Niemann-pick C1-like 1 (NPC1L1) protein in intestinal and hepatic cholesterol transport. | 2011 |
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| 43 |
20953676 | Human NPC1L1 expression is positively regulated by PPARα. | 2011 Feb |
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| 44 |
21437027 | Phytosterols and phytosterolemia: gene-diet interactions. | 2011 Feb |
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| 45 |
21683156 | Ezetimibe restores biliary cholesterol excretion in mice expressing Niemann-Pick C1-Like 1 only in liver. | 2011 Sep |
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| 46 |
22358082 | Ezetimibe--a new approach in hypercholesterolemia management. | 2011 |
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| 47 |
19907422 | Transporters as drug targets: discovery and development of NPC1L1 inhibitors. | 2010 Jan |
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| 48 |
20222991 | NPC1L1 inhibitor ezetimibe is a reliable therapeutic agent for non-obese patients with nonalcoholic fatty liver disease. | 2010 Mar 12 |
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| 49 |
20403165 | Curcumin inhibits cholesterol uptake in Caco-2 cells by down-regulation of NPC1L1 expression. | 2010 Apr 19 |
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20543520 | Current therapy for patients with sitosterolemia--effect of ezetimibe on plant sterol metabolism. | 2010 Sep 30 |
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