| 1 |
35597782 | FASN promotes lymph node metastasis in cervical cancer via cholesterol reprogramming and lymphangiogenesis. | 2022 May 21 |
3 |
| 2 |
34483846 | Inhibition of Fatty Acid Synthesis Aggravates Brain Injury, Reduces Blood-Brain Barrier Integrity and Impairs Neurological Recovery in a Murine Stroke Model. | 2021 |
1 |
| 3 |
34977875 | Altering phosphoinositides in high-fat diet-associated prostate tumor xenograft growth. | 2021 Dec |
1 |
| 4 |
31678479 | Fatty acid synthase and stearoyl-CoA desaturase-1 are conserved druggable cofactors of Old World Alphavirus genome replication. | 2019 Dec |
1 |
| 5 |
27918556 | Effects of fatty acid synthase inhibitors on lymphatic vessels: an in vitro and in vivo study in a melanoma model. | 2017 Feb |
1 |
| 6 |
28260110 | Inhibitory effect of emodin on fatty acid synthase, colon cancer proliferation and apoptosis. | 2017 Apr |
1 |
| 7 |
28400509 | Oncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma. | 2017 Apr 25 |
1 |
| 8 |
29113229 | Fatty acid synthase affects expression of ErbB receptors in epithelial to mesenchymal transition of breast cancer cells and invasive ductal carcinoma. | 2017 Nov |
2 |
| 9 |
26109148 | Loss of fatty acid synthase suppresses the malignant phenotype of colorectal cancer cells by down-regulating energy metabolism and mTOR signaling pathway. | 2016 Jan |
1 |
| 10 |
26808816 | Inhibition of Fatty Acid Synthase Decreases Expression of Stemness Markers in Glioma Stem Cells. | 2016 |
1 |
| 11 |
26936618 | FASN, ErbB2-mediated glycolysis is required for breast cancer cell migration. | 2016 May |
1 |
| 12 |
27713913 | The metastasis inducer CCN1 (CYR61) activates the fatty acid synthase (FASN)-driven lipogenic phenotype in breast cancer cells. | 2016 |
1 |
| 13 |
27765901 | A FASN-TGF-β1-FASN regulatory loop contributes to high EMT/metastatic potential of cisplatin-resistant non-small cell lung cancer. | 2016 Aug 23 |
2 |
| 14 |
25825864 | Novel Pathway for Hypoxia-Induced Proliferation and Migration in Human Mesenchymal Stem Cells: Involvement of HIF-1α, FASN, and mTORC1. | 2015 Jul |
1 |
| 15 |
25947066 | Fatty acid synthase overexpression: target for therapy and reversal of chemoresistance in ovarian cancer. | 2015 May 7 |
2 |
| 16 |
26484401 | Inhibition of Fatty Acid Synthase Sensitizes Prostate Cancer Cells to Radiotherapy. | 2015 Nov |
1 |
| 17 |
24520215 | Fatty acid synthase mediates the epithelial-mesenchymal transition of breast cancer cells. | 2014 |
2 |
| 18 |
24866893 | The mTOR inhibitor rapamycin synergizes with a fatty acid synthase inhibitor to induce cytotoxicity in ER/HER2-positive breast cancer cells. | 2014 |
1 |
| 19 |
23108760 | Fatty acid synthase inhibitor cerulenin inhibits topoisomerase I catalytic activity and augments SN-38-induced apoptosis. | 2013 Feb |
2 |
| 20 |
23441619 | Fatty acid synthase inhibition induces differential expression of genes involved in apoptosis and cell proliferation in ocular cancer cells. | 2013 |
1 |
| 21 |
23754252 | Enhanced antitumor activity of cerulenin combined with oxaliplatin in human colon cancer cells. | 2013 Aug |
1 |
| 22 |
23816424 | Biochemical changes accompanying apoptotic cell death in retinoblastoma cancer cells treated with lipogenic enzyme inhibitors. | 2013 Sep |
2 |
| 23 |
22771636 | Inhibition of fatty acid synthase supresses osteosarcoma cell invasion and migration. | 2012 Apr-Jun |
2 |
| 24 |
23135268 | G protein-coupled estrogen receptor mediates the up-regulation of fatty acid synthase induced by 17β-estradiol in cancer cells and cancer-associated fibroblasts. | 2012 Dec 21 |
1 |
| 25 |
21170507 | Thiazolidinediones/PPARγ agonists and fatty acid synthase inhibitors as an experimental combination therapy for prostate cancer. | 2011 Feb |
1 |
| 26 |
21389266 | Antidiabetic and antisteatotic effects of the selective fatty acid synthase (FAS) inhibitor platensimycin in mouse models of diabetes. | 2011 Mar 29 |
1 |
| 27 |
21643005 | A novel positive feedback loop involving FASN/p-ERK1/2/5-LOX/LTB4/FASN sustains high growth of breast cancer cells. | 2011 Jul |
1 |
| 28 |
19932008 | UV decreases the synthesis of free fatty acids and triglycerides in the epidermis of human skin in vivo, contributing to development of skin photoaging. | 2010 Jan |
1 |
| 29 |
20126469 | A mutant of hepatitis B virus X protein (HBxDelta127) promotes cell growth through a positive feedback loop involving 5-lipoxygenase and fatty acid synthase. | 2010 Feb |
2 |
| 30 |
20173757 | A mutant of HBx (HBxDelta127) promotes hepatoma cell growth via sterol regulatory element binding protein 1c involving 5-lipoxygenase. | 2010 Mar |
2 |
| 31 |
20372807 | Fatty acid synthesis is a therapeutic target in human liposarcoma. | 2010 May |
1 |
| 32 |
20373869 | Fatty acid synthase as a potential therapeutic target in cancer. | 2010 Apr |
1 |
| 33 |
20511185 | Fatty acid synthase as a novel target for meningioma therapy. | 2010 Aug |
2 |
| 34 |
20973802 | Novel anti-fatty acid synthase compounds with anti-cancer activity in HER2+ breast cancer. | 2010 Oct |
1 |
| 35 |
23181152 | Chemical inhibition of fatty acid synthase: molecular docking analysis and biochemical validation in ocular cancer cells. | 2010 Dec |
3 |
| 36 |
18259941 | The synthetic triterpenoid CDDO-Im inhibits fatty acid synthase expression and has antiproliferative and proapoptotic effects in human liposarcoma cells. | 2008 Mar |
1 |
| 37 |
18410446 | Fatty acid synthase is a novel therapeutic target in multiple myeloma. | 2008 May |
3 |
| 38 |
18543396 | Increased fatty acid synthase as a potential therapeutic target in multiple myeloma. | 2008 Jun |
1 |
| 39 |
18723500 | Fatty acid synthase inhibition results in a magnetic resonance-detectable drop in phosphocholine. | 2008 Aug |
1 |
| 40 |
17786362 | Inhibition of Fatty Acid Synthase (FASN) synergistically enhances the efficacy of 5-fluorouracil in breast carcinoma cells. | 2007 Oct |
3 |
| 41 |
17904792 | Fatty acid synthase inhibitors cerulenin and C75 retard growth and induce caspase-dependent apoptosis in human melanoma A-375 cells. | 2007 Oct |
2 |
| 42 |
16969344 | Fatty acid synthase: a novel target for antiglioma therapy. | 2006 Oct 9 |
1 |
| 43 |
17168665 | Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents? | 2006 Dec |
1 |
| 44 |
17343199 | [Study on proliferation inhibiting and apoptosis inducing effects of cerulenin on multiple myeloma cells]. | 2006 Oct |
1 |
| 45 |
15617971 | A pilot study of fatty acid metabolism in oral squamous cell carcinoma. | 2005 Jan |
2 |
| 46 |
15806173 | Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells. | 2005 May 19 |
2 |
| 47 |
15878185 | Fatty acid metabolism as a target for obesity treatment. | 2005 May 19 |
1 |
| 48 |
15974853 | Proliferation of fibroblasts cultured from normal gingiva and hereditary gingival fibromatosis is dependent on fatty acid synthase activity. | 2005 Feb |
2 |
| 49 |
14615481 | C75, a fatty acid synthase inhibitor, modulates AMP-activated protein kinase to alter neuronal energy metabolism. | 2004 Jan 30 |
1 |
| 50 |
14767544 | Novel signaling molecules implicated in tumor-associated fatty acid synthase-dependent breast cancer cell proliferation and survival: Role of exogenous dietary fatty acids, p53-p21WAF1/CIP1, ERK1/2 MAPK, p27KIP1, BRCA1, and NF-kappaB. | 2004 Mar |
4 |