| 1 |
32275951 | Evaluation of FASN inhibitors by a versatile toolkit reveals differences in pharmacology between human and rodent FASN preparations and in antiproliferative efficacy in vitro vs. in situ in human cancer cells. | 2020 Apr 7 |
2 |
| 2 |
31164796 | Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells. | 2019 |
1 |
| 3 |
28260110 | Inhibitory effect of emodin on fatty acid synthase, colon cancer proliferation and apoptosis. | 2017 Apr |
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| 4 |
28427229 | NADPH accumulation is responsible for apoptosis in breast cancer cells induced by fatty acid synthase inhibition. | 2017 May 16 |
3 |
| 5 |
28962653 | Cellular fatty acid synthase is required for late stages of HIV-1 replication. | 2017 Sep 29 |
1 |
| 6 |
26586251 | Development of a Medium-Throughput Targeted LCMS Assay to Detect Endogenous Cellular Levels of Malonyl-CoA to Screen Fatty Acid Synthase Inhibitors. | 2016 Feb |
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| 7 |
26680361 | Regulating effect of β-ketoacyl synthase domain of fatty acid synthase on fatty acyl chain length in de novo fatty acid synthesis. | 2016 Mar |
1 |
| 8 |
25924694 | Potent Inhibitory Effect of Chinese Dietary Spices on Fatty Acid Synthase. | 2015 Sep |
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| 9 |
26364942 | Progress in the development of fatty acid synthase inhibitors as anticancer targets. | 2015 Oct 15 |
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| 10 |
24894151 | Alpha-mangostin inhibits intracellular fatty acid synthase and induces apoptosis in breast cancer cells. | 2014 Jun 3 |
1 |
| 11 |
24957042 | Inhibitory effects of sea buckthorn procyanidins on fatty acid synthase and MDA-MB-231 cells. | 2014 Oct |
4 |
| 12 |
25009654 | Quercetin induces HepG2 cell apoptosis by inhibiting fatty acid biosynthesis. | 2014 Aug |
1 |
| 13 |
22728958 | Mammalian fatty acid synthase activity from crude tissue lysates tracing ¹³C-labeled substrates using gas chromatography-mass spectrometry. | 2012 Sep 15 |
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| 14 |
23214141 | [Metabolic and regulatory function of fatty acid synthase]. | 2012 |
2 |
| 15 |
19782152 | Fine-tuning the lipogenic/lipolytic balance to optimize the metabolic requirements of cancer cell growth: molecular mechanisms and therapeutic perspectives. | 2010 Mar |
2 |
| 16 |
20074555 | Evaluation of inhibition of fatty acid synthase by ursolic acid: positive cooperation mechanism. | 2010 Feb 12 |
3 |
| 17 |
18201766 | A substitutive substrate for measurements of beta-ketoacyl reductases in two fatty acid synthase systems. | 2008 Apr 24 |
1 |
| 18 |
17168665 | Pharmacological inhibitors of Fatty Acid Synthase (FASN)--catalyzed endogenous fatty acid biogenesis: a new family of anti-cancer agents? | 2006 Dec |
4 |
| 19 |
14999013 | Inhibitory effects of flavonoids on animal fatty acid synthase. | 2004 Jan |
1 |
| 20 |
11064249 | The activity of fatty acid synthase of epidermal keratinocytes is regulated in the lower stratum spinousum and the stratum basale by local inflammation rather than by circulating hormones. | 2000 Nov |
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| 21 |
8962082 | Cloning and expression of the multifunctional human fatty acid synthase and its subdomains in Escherichia coli. | 1996 Dec 10 |
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| 22 |
7567999 | Human fatty acid synthase: properties and molecular cloning. | 1995 Sep 12 |
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| 23 |
8022791 | Fatty acid synthesis: a potential selective target for antineoplastic therapy. | 1994 Jul 5 |
5 |
| 24 |
3530833 | Enzymatic reduction of phenylglyoxal and 2,3-butanedione, two commonly used arginine-modifying reagents, by the ketoacyl reductase domain of fatty acid synthase. | 1986 |
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