| 1 |
35349401 | The RNA-dependent RNA polymerase of the infectious pancreatic necrosis virus is linked to viral mRNA acting as a cap substitute. | 2022 Mar |
1 |
| 2 |
33189285 | Acetate regulates milk fat synthesis through the mammalian target of rapamycin/eukaryotic initiation factor 4E signaling pathway in bovine mammary epithelial cells. | 2021 Jan |
1 |
| 3 |
34255842 | capCLIP: a new tool to probe translational control in human cells through capture and identification of the eIF4E-mRNA interactome. | 2021 Oct 11 |
1 |
| 4 |
31782083 | Eukaryotic initiation factor 4E is a novel effector of mTORC1 signaling pathway in cross talk with Mnk1. | 2020 Feb |
4 |
| 5 |
31921404 | TSC patient-derived isogenic neural progenitor cells reveal altered early neurodevelopmental phenotypes and rapamycin-induced MNK-eIF4E signaling. | 2020 |
2 |
| 6 |
30552925 | Eukaryotic Initiation Factor 4E (eIF4E) sequestration mediates 4E-BP1 response to rapamycin. | 2019 Mar 15 |
3 |
| 7 |
29850566 | Rapamycin Inhibits the Growth and Collagen Production of Fibroblasts Derived from Human Urethral Scar Tissue. | 2018 |
1 |
| 8 |
30297804 | MNK1 inhibitor CGP57380 overcomes mTOR inhibitor-induced activation of eIF4E: the mechanism of synergic killing of human T-ALL cells. | 2018 Dec |
1 |
| 9 |
27050281 | CGP57380 enhances efficacy of RAD001 in non-small cell lung cancer through abrogating mTOR inhibition-induced phosphorylation of eIF4E and activating mitochondrial apoptotic pathway. | 2016 May 10 |
2 |
| 10 |
27245614 | The 4E-BP-eIF4E axis promotes rapamycin-sensitive growth and proliferation in lymphocytes. | 2016 May 31 |
1 |
| 11 |
25439783 | The 4E-BP1/eIF4E ratio is a determinant for rapamycin response in esophageal cancer cells. | 2015 Jan |
4 |
| 12 |
25659819 | Rapamycin-induced G1 cell cycle arrest employs both TGF-β and Rb pathways. | 2015 May 1 |
2 |
| 13 |
25193863 | Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells. | 2014 Sep 30 |
1 |
| 14 |
26097864 | New insights into malignant cell survival mechanisms in medulloblastoma. | 2014 |
2 |
| 15 |
23376634 | Inhibition of S6 kinase suppresses the apoptotic effect of eIF4E ablation by inducing TGF-β-dependent G1 cell cycle arrest. | 2013 Jun 10 |
3 |
| 16 |
23831578 | Rapamycin enhances eIF4E phosphorylation by activating MAP kinase-interacting kinase 2a (Mnk2a). | 2013 Aug 19 |
3 |
| 17 |
23872707 | Modifying chemotherapy response by targeted inhibition of eukaryotic initiation factor 4A. | 2013 Jul 19 |
1 |
| 18 |
22556409 | The PP242 mammalian target of rapamycin (mTOR) inhibitor activates extracellular signal-regulated kinase (ERK) in multiple myeloma cells via a target of rapamycin complex 1 (TORC1)/eukaryotic translation initiation factor 4E (eIF-4E)/RAF pathway and activation is a mechanism of resistance. | 2012 Jun 22 |
1 |
| 19 |
22767218 | Cap-dependent mRNA translation and the ubiquitin-proteasome system cooperate to promote ERBB2-dependent esophageal cancer phenotype. | 2012 Sep |
1 |
| 20 |
21576371 | Relieving autophagy and 4EBP1 from rapamycin resistance. | 2011 Jul |
1 |
| 21 |
21949767 | Simultaneous inhibition of mTOR-containing complex 1 (mTORC1) and MNK induces apoptosis of cutaneous T-cell lymphoma (CTCL) cells. | 2011 |
1 |
| 22 |
22071574 | High-dose rapamycin induces apoptosis in human cancer cells by dissociating mTOR complex 1 and suppressing phosphorylation of 4E-BP1. | 2011 Nov 15 |
2 |
| 23 |
20177775 | Effect of combination treatment of rapamycin and isoflavones on mTOR pathway in human glioblastoma (U87) cells. | 2010 Jul |
4 |
| 24 |
20664001 | Negative regulatory effects of Mnk kinases in the generation of chemotherapy-induced antileukemic responses. | 2010 Oct |
1 |
| 25 |
19641186 | Inhibition of histone deacetylase overcomes rapamycin-mediated resistance in diffuse large B-cell lymphoma by inhibiting Akt signaling through mTORC2. | 2009 Oct 1 |
1 |
| 26 |
18361417 | Cyclin B synthesis and rapamycin-sensitive regulation of protein synthesis during starfish oocyte meiotic divisions. | 2008 Nov |
1 |
| 27 |
18644990 | eIF4E knockdown decreases breast cancer cell growth without activating Akt signaling. | 2008 Jul |
3 |
| 28 |
18701474 | S6K1 plays a key role in glial transformation. | 2008 Aug 15 |
1 |
| 29 |
18809972 | Phosphorylation of eIF4E by MNKs supports protein synthesis, cell cycle progression and proliferation in prostate cancer cells. | 2008 Dec |
1 |
| 30 |
18981735 | Overcoming mTOR inhibition-induced paradoxical activation of survival signaling pathways enhances mTOR inhibitors' anticancer efficacy. | 2008 Dec |
2 |
| 31 |
17382186 | Upstream signaling inhibition enhances rapamycin effect on growth of kidney cancer cells. | 2007 Mar |
2 |
| 32 |
18082048 | [Rapamycin affects eIF- 4E expression in rat myocardial fibroblasts infected by Coxsackievirus B3]. | 2007 Dec |
1 |
| 33 |
16715128 | Rapamycin inhibits cell motility by suppression of mTOR-mediated S6K1 and 4E-BP1 pathways. | 2006 Nov 9 |
1 |
| 34 |
16103051 | Activation of Akt and eIF4E survival pathways by rapamycin-mediated mammalian target of rapamycin inhibition. | 2005 Aug 15 |
2 |
| 35 |
16242075 | Disruption of parallel and converging signaling pathways contributes to the synergistic antitumor effects of simultaneous mTOR and EGFR inhibition in GBM cells. | 2005 Oct |
2 |
| 36 |
15190216 | Reversing drug resistance in vivo. | 2004 Jul |
1 |
| 37 |
15292274 | Molecular cross-talk between MEK1/2 and mTOR signaling during recovery of 293 cells from hypertonic stress. | 2004 Oct 29 |
1 |
| 38 |
15355912 | Overexpressed eIF4E is functionally active in surgical margins of head and neck cancer patients via activation of the Akt/mammalian target of rapamycin pathway. | 2004 Sep 1 |
1 |
| 39 |
11847216 | 4E-binding proteins, the suppressors of eukaryotic initiation factor 4E, are down-regulated in cells with acquired or intrinsic resistance to rapamycin. | 2002 Apr 19 |
1 |
| 40 |
10212283 | A potential role for extracellular signal-regulated kinases in prostaglandin F2alpha-induced protein synthesis in smooth muscle cells. | 1999 Apr 30 |
1 |
| 41 |
10454551 | Cell cycle progression and proliferation despite 4BP-1 dephosphorylation. | 1999 Sep |
2 |
| 42 |
9458731 | Signal transduction pathways involved in the regulation of protein synthesis by insulin in L6 myoblasts. | 1998 Jan |
1 |
| 43 |
9160663 | Macrophage inflammatory protein-1alpha and interferon-inducible protein 10 inhibit synergistically induced growth factor stimulation of MAP kinase activity and suppress phosphorylation of eukaryotic initiation factor 4E and 4E binding protein 1. | 1997 May 15 |
1 |
| 44 |
8599949 | Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation. | 1996 Feb 1 |
1 |
| 45 |
7629182 | Control of PHAS-I by insulin in 3T3-L1 adipocytes. Synthesis, degradation, and phosphorylation by a rapamycin-sensitive and mitogen-activated protein kinase-independent pathway. | 1995 Aug 4 |
2 |