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eukaryotic translation initiation factor 4E ; Homo sapiens







44 Article(s)
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1 28322282 Maternal immune activation dysregulation of the fetal brain transcriptome and relevance to the pathophysiology of autism spectrum disorder. 2018 Apr 2
2 28468879 Regulation of Tacaribe Mammarenavirus Translation: Positive 5' and Negative 3' Elements and Role of Key Cellular Factors. 2017 Jul 15 1
3 28487484 Cap-binding protein 4EHP effects translation silencing by microRNAs. 2017 May 23 1
4 28539821 Stabilization of 4E-BP1 by PI3K kinase and its involvement in CHK2 phosphorylation in the cellular response to radiation. 2017 2
5 27002144 Human Cells Cultured under Physiological Oxygen Utilize Two Cap-binding Proteins to recruit Distinct mRNAs for Translation. 2016 May 13 1
6 27114554 Importin 8 mediates m7G cap-sensitive nuclear import of the eukaryotic translation initiation factor eIF4E. 2016 May 10 1
7 25839159 Translation initiation complex eIF4F is a therapeutic target for dual mTOR kinase inhibitors in non-Hodgkin lymphoma. 2015 Apr 20 1
8 23624914 ERK and AKT signaling cooperate to translationally regulate survivin expression for metastatic progression of colorectal cancer. 2014 Apr 3 2
9 25356869 An eIF4E-interacting peptide induces cell death in cancer cell lines. 2014 Oct 30 1
10 23547259 Inactivation of the mTORC1-eukaryotic translation initiation factor 4E pathway alters stress granule formation. 2013 Jun 1
11 23667251 Hypoxia-inducible factor-1α (HIF-1α) promotes cap-dependent translation of selective mRNAs through up-regulating initiation factor eIF4E1 in breast cancer cells under hypoxia conditions. 2013 Jun 28 1
12 23901100 Human eIF4E promotes mRNA restructuring by stimulating eIF4A helicase activity. 2013 Aug 13 1
13 22392810 Development of biochemical assays for the identification of eIF4E-specific inhibitors. 2012 Jun 2
14 22495651 Cap-dependent translation initiation factor eIF4E: an emerging anticancer drug target. 2012 Jul 1
15 20227039 Genetic dissection of the oncogenic mTOR pathway reveals druggable addiction to translational control via 4EBP-eIF4E. 2010 Mar 16 1
16 19159466 The human Ago2 MC region does not contain an eIF4E-like mRNA cap binding motif. 2009 Jan 21 1
17 18343217 Ectopic expression of eIF4E-transporter triggers the movement of eIF4E into P-bodies, inhibiting steady-state translation but not the pioneer round of translation. 2008 May 16 1
18 17220299 Thioredoxin 1 and thioredoxin 2 have opposed regulatory functions on hypoxia-inducible factor-1alpha. 2007 Mar 9 1
19 17369309 Weak binding affinity of human 4EHP for mRNA cap analogs. 2007 May 1
20 17440067 Phenethyl isothiocyanate, a cancer chemopreventive constituent of cruciferous vegetables, inhibits cap-dependent translation by regulating the level and phosphorylation of 4E-BP1. 2007 Apr 15 1
21 17584618 Substrate-dependent targeting of eukaryotic translation initiation factor 4A by pateamine A: negation of domain-linker regulation of activity. 2007 Jun 1
22 17638893 Eukaryotic translation initiation factor 4E induced progression of primary human mammary epithelial cells along the cancer pathway is associated with targeted translational deregulation of oncogenic drivers and inhibitors. 2007 Jul 15 2
23 16405910 Folding transitions during assembly of the eukaryotic mRNA cap-binding complex. 2006 Mar 3 2
24 16515558 Mnk is a negative regulator of cap-dependent translation in Aplysia neurons. 2006 Apr 1
25 16531451 Global alterations in mRNA polysomal recruitment in a cell model of colorectal cancer progression to metastasis. 2006 Jul 1
26 16626853 Potyvirus terminal protein VPg, effector of host eukaryotic initiation factor eIF4E. 2006 Jul 2
27 17036047 Cap-free structure of eIF4E suggests a basis for conformational regulation by its ligands. 2006 Nov 1 1
28 15766285 A mutant of eukaryotic protein synthesis initiation factor eIF4E(K119A) has an increased binding affinity for both m7G cap analogues and eIF4G peptides. 2005 Mar 22 2
29 15901615 4E-binding protein phosphorylation and eukaryotic initiation factor-4E release are required for airway smooth muscle hypertrophy. 2005 Aug 3
30 15220445 Structural basis for competitive inhibition of eIF4G-Mnk1 interaction by the adenovirus 100-kilodalton protein. 2004 Jul 3
31 15491137 Thermodynamics of mRNA 5' cap binding by eukaryotic translation initiation factor eIF4E. 2004 Oct 26 1
32 12691746 Structural features of human initiation factor 4E, studied by X-ray crystal analyses and molecular dynamics simulations. 2003 Apr 25 1
33 14507920 Ser-64 and Ser-111 in PHAS-I are dispensable for insulin-stimulated dissociation from eIF4E. 2003 Nov 28 1
34 14690557 [Contribution of eukaryotic initiation factor-4E inhibition to heparanase expression and activity in human colon adenocarcinoma cell line LS-174T]. 2003 Nov 2
35 11463832 Negative regulation of protein translation by mitogen-activated protein kinase-interacting kinases 1 and 2. 2001 Aug 1
36 11483729 Activity of the hepatitis A virus IRES requires association between the cap-binding translation initiation factor (eIF4E) and eIF4G. 2001 Sep 1
37 11513750 Glucose exerts a permissive effect on the regulation of the initiation factor 4E binding protein 4E-BP1. 2001 Sep 1 3
38 10611225 Eukaryotic translation initiation factor 4E (eIF4E) binding site and the middle one-third of eIF4GI constitute the core domain for cap-dependent translation, and the C-terminal one-third functions as a modulatory region. 2000 Jan 2
39 10882133 Interaction between a poly(A)-specific ribonuclease and the 5' cap influences mRNA deadenylation rates in vitro. 2000 Mar 1
40 9582349 Cloning and characterization of 4EHP, a novel mammalian eIF4E-related cap-binding protein. 1998 May 22 2
41 8610440 Phosphorylation state of the cap-binding protein eIF4E during viral infection. 1996 Mar 15 1
42 8971030 Rapamycin stimulates viral protein synthesis and augments the shutoff of host protein synthesis upon picornavirus infection. 1996 Dec 1
43 8505316 Characterization of wild-type and Ser53 mutant eukaryotic initiation factor 4E overexpression in mammalian cells. 1993 Jun 5 3
44 2386781 Phenyl azide substituted and benzophenone-substituted phosphonamides of 7-methylguanosine 5'-triphosphate as photoaffinity probes for protein synthesis initiation factor eIF-4E and a proteolytic fragment containing the cap-binding site. 1990 Jun 12 2