| 1 |
35203342 | Impaired Function of PLEKHG2, a Rho-Guanine Nucleotide-Exchange Factor, Disrupts Corticogenesis in Neurodevelopmental Phenotypes. | 2022 Feb 16 |
1 |
| 2 |
33284659 | Elevated TIAM2 expression promotes tumor progression and is associated with unfavorable prognosis in pancreatic cancer. | 2021 Jan |
1 |
| 3 |
33660564 | Biallelic ELMO3 mutations and loss of function for DOCK-mediated RAC1 activation result in intellectual disability. | 2021 Mar 4 |
1 |
| 4 |
35174167 | Role of ARHGEF3 as a GEF and mTORC2 Regulator. | 2021 |
1 |
| 5 |
32048687 | Optogenetic Rac1 engineered from membrane lipid-binding RGS-LOV for inducible lamellipodia formation. | 2020 Mar 1 |
1 |
| 6 |
32339198 | Mutations in SPATA13/ASEF2 cause primary angle closure glaucoma. | 2020 Apr |
1 |
| 7 |
32456244 | Pleiotropic Roles of Calmodulin in the Regulation of KRas and Rac1 GTPases: Functional Diversity in Health and Disease. | 2020 May 23 |
1 |
| 8 |
32978791 | The guanine nucleotide exchange factor FLJ00068 activates Rac1 in adipocyte insulin signaling. | 2020 Dec |
2 |
| 9 |
33200195 | Mechanisms and consequences of dysregulation of the Tiam family of Rac activators in disease. | 2020 Dec 18 |
1 |
| 10 |
28489964 | Specific activation of PLEKHG2-induced serum response element-dependent gene transcription by four-and-a-half LIM domains (FHL) 1, but not FHL2 or FHL3. | 2019 Sep |
1 |
| 11 |
30853411 | Structural Basis for the Dual Substrate Specificity of DOCK7 Guanine Nucleotide Exchange Factor. | 2019 May 7 |
1 |
| 12 |
31089935 | DBS is activated by EPHB2/SRC signaling-mediated tyrosine phosphorylation in HEK293 cells. | 2019 Sep |
1 |
| 13 |
31300985 | Functional Regulation of an Oxidative Stress Mediator, Rac1, in Diabetic Retinopathy. | 2019 Dec |
2 |
| 14 |
29130632 | DOCK3-related neurodevelopmental syndrome: Biallelic intragenic deletion of DOCK3 in a boy with developmental delay and hypotonia. | 2018 Jan |
1 |
| 15 |
29844364 | STEF/TIAM2-mediated Rac1 activity at the nuclear envelope regulates the perinuclear actin cap. | 2018 May 29 |
1 |
| 16 |
29967243 | Rac1 Nanoscale Organization on the Plasma Membrane Is Driven by Lipid Binding Specificity Encoded in the Membrane Anchor. | 2018 Sep 15 |
1 |
| 17 |
30108175 | HGF-induced formation of the MET-AXL-ELMO2-DOCK180 complex promotes RAC1 activation, receptor clustering, and cancer cell migration and invasion. | 2018 Oct 5 |
2 |
| 18 |
27267709 | Every day I'm rufflin': Calcium sensing and actin dynamics in the growth factor-independent membrane ruffling of professional phagocytes. | 2017 Apr 3 |
1 |
| 19 |
27669437 | The focal adhesion-associated proteins DOCK5 and GIT2 comprise a rheostat in control of epithelial invasion. | 2017 Mar 30 |
1 |
| 20 |
28807941 | The Rac GTPase in Cancer: From Old Concepts to New Paradigms. | 2017 Oct 15 |
1 |
| 21 |
29178143 | Peptide modulators of Rac1/Tiam1 protein-protein interaction: An alternative approach for cardiovascular diseases. | 2017 Nov 27 |
1 |
| 22 |
26887924 | Differential Rac1 signalling by guanine nucleotide exchange factors implicates FLII in regulating Rac1-driven cell migration. | 2016 Feb 18 |
2 |
| 23 |
27152953 | Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors. | 2016 Aug 2 |
2 |
| 24 |
27182061 | Expanding functions of GIT Arf GTPase-activating proteins, PIX Rho guanine nucleotide exchange factors and GIT-PIX complexes. | 2016 May 15 |
1 |
| 25 |
27693992 | The redox mechanism for vascular barrier dysfunction associated with metabolic disorders: Glutathionylation of Rac1 in endothelial cells. | 2016 Oct |
2 |
| 26 |
25289457 | Redox regulation of Rac1 by thiol oxidation. | 2015 Feb |
4 |
| 27 |
25332238 | Axl phosphorylates Elmo scaffold proteins to promote Rac activation and cell invasion. | 2015 Jan |
1 |
| 28 |
25516960 | RhoC Is an Unexpected Target of RhoGDI2 in Prevention of Lung Colonization of Bladder Cancer. | 2015 Mar |
1 |
| 29 |
25635515 | Augmented AMPK activity inhibits cell migration by phosphorylating the novel substrate Pdlim5. | 2015 Jan 30 |
1 |
| 30 |
25655724 | Supervillin binds the Rac/Rho-GEF Trio and increases Trio-mediated Rac1 activation. | 2015 Jan |
3 |
| 31 |
24607953 | The on-off relationship of Rho and Rac during integrin-mediated adhesion and cell migration. | 2014 |
1 |
| 32 |
25014207 | Liposome reconstitution and modulation of recombinant prenylated human Rac1 by GEFs, GDI1 and Pak1. | 2014 |
3 |
| 33 |
23718289 | Prenylation and membrane localization of Cdc42 are essential for activation by DOCK7. | 2013 Jun 25 |
2 |
| 34 |
24043306 | Phosphorylation of Rac1 T108 by extracellular signal-regulated kinase in response to epidermal growth factor: a novel mechanism to regulate Rac1 function. | 2013 Nov |
3 |
| 35 |
22238672 | The N-terminal DH-PH domain of Trio induces cell spreading and migration by regulating lamellipodia dynamics in a Rac1-dependent fashion. | 2012 |
1 |
| 36 |
23014990 | ELMO domains, evolutionary and functional characterization of a novel GTPase-activating protein (GAP) domain for Arf protein family GTPases. | 2012 Nov 16 |
1 |
| 37 |
21943825 | Inactivation of Rac1 reduces Trastuzumab resistance in PTEN deficient and insulin-like growth factor I receptor overexpressing human breast cancer SKBR3 cells. | 2011 Dec 26 |
1 |
| 38 |
20237902 | The role of Crk/Dock180/Rac1 pathway in the malignant behavior of human ovarian cancer cell SKOV3. | 2010 Jan |
1 |
| 39 |
20444104 | The Candida albicans ELMO homologue functions together with Rac1 and Dck1, upstream of the MAP Kinase Cek1, in invasive filamentous growth. | 2010 Jun |
1 |
| 40 |
19088377 | Rac GTPases play critical roles in early T-cell development. | 2009 Apr 23 |
1 |
| 41 |
19525225 | Adenomatous polyposis coli and Asef function downstream of hepatocyte growth factor and phosphatidylinositol 3-kinase. | 2009 Aug 14 |
1 |
| 42 |
19933863 | Signal-transducing adaptor protein-2 regulates stromal cell-derived factor-1 alpha-induced chemotaxis in T cells. | 2009 Dec 15 |
1 |
| 43 |
18267089 | Rho-kinase phosphorylates PAR-3 and disrupts PAR complex formation. | 2008 Feb |
1 |
| 44 |
18374160 | Characterization of EHT 1864, a novel small molecule inhibitor of Rac family small GTPases. | 2008 |
1 |
| 45 |
18482007 | Activation of the small GTPase Rac1 by a specific guanine-nucleotide-exchange factor suffices to induce glucose uptake into skeletal-muscle cells. | 2008 Nov |
1 |
| 46 |
18589439 | Structural basis of guanine nucleotide exchange mediated by the T-cell essential Vav1. | 2008 Jul 25 |
1 |
| 47 |
18596235 | The DHR1 domain of DOCK180 binds to SNX5 and regulates cation-independent mannose 6-phosphate receptor transport. | 2008 Sep |
1 |
| 48 |
17214551 | Asef is a Cdc42-specific guanine nucleotide exchange factor. | 2007 Jan |
1 |
| 49 |
17570359 | RhoG regulates anoikis through a phosphatidylinositol 3-kinase-dependent mechanism. | 2007 Aug 1 |
1 |
| 50 |
17686471 | VEGF-induced Rac1 activation in endothelial cells is regulated by the guanine nucleotide exchange factor Vav2. | 2007 Sep 10 |
1 |