Hydrogen Peroxide

Rac family small GTPase 1 ; Homo sapiens







23 Article(s)
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1 35453403 Reciprocal Regulation of Shh Trafficking and H2O2 Levels via a Noncanonical BOC-Rac1 Pathway. 2022 Apr 5 2
2 31973815 P-Tyr42 RhoA GTPase amplifies superoxide formation through p47phox, phosphorylated by ROCK. 2020 Mar 19 1
3 29425589 Puerarin attenuates angiotensin II-induced cardiac fibroblast proliferation via the promotion of catalase activity and the inhibition of hydrogen peroxide-dependent Rac-1 activation. 2018 Jan 3
4 28761330 Epigenetic memory of oxidative stress: does nephrilin exert its protective effects via Rac1? 2017 1
5 27380944 Stochastic modelling suggests that an elevated superoxide anion - hydrogen peroxide ratio can drive extravascular phagocyte transmigration by lamellipodium formation. 2016 Oct 21 1
6 24550450 Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium. 2014 Mar 4 1
7 23345605 Acquisition of the metastatic phenotype is accompanied by H2O2-dependent activation of the p130Cas signaling complex. 2013 Mar 2
8 24064382 Oxidative stress enhances Axl-mediated cell migration through an Akt1/Rac1-dependent mechanism. 2013 Dec 2
9 21814770 Selective Rac1 inhibition protects renal tubular epithelial cells from oxalate-induced NADPH oxidase-mediated oxidative cell injury. 2012 Aug 1
10 22157762 Mitochondrial Rac1 GTPase import and electron transfer from cytochrome c are required for pulmonary fibrosis. 2012 Jan 27 4
11 22286230 Dieckol from Ecklonia cava suppresses the migration and invasion of HT1080 cells by inhibiting the focal adhesion kinase pathway downstream of Rac1-ROS signaling. 2012 Feb 1
12 22773836 Angiotensin-II and MARCKS: a hydrogen peroxide- and RAC1-dependent signaling pathway in vascular endothelium. 2012 Aug 17 1
13 21525435 Role of Rac1 in regulation of NOX5-S function in Barrett's esophageal adenocarcinoma cells. 2011 Aug 3
14 21958220 NOX2 activated by α1-adrenoceptors modulates hepatic metabolic routes stimulated by β-adrenoceptors. 2011 Nov 1
15 16354686 Nox2 and Rac1 regulate H2O2-dependent recruitment of TRAF6 to endosomal interleukin-1 receptor complexes. 2006 Jan 1
16 16927023 Activation of mitogen-activated protein kinases is essential for hydrogen peroxide -induced apoptosis in retinal pigment epithelial cells. 2006 Nov 3
17 16055727 Signal regulatory protein alpha ligation induces macrophage nitric oxide production through JAK/STAT- and phosphatidylinositol 3-kinase/Rac1/NAPDH oxidase/H2O2-dependent pathways. 2005 Aug 2
18 15121857 Sequential activation of phosphatidylinositol 3-kinase, beta Pix, Rac1, and Nox1 in growth factor-induced production of H2O2. 2004 May 1
19 12556491 Rho family GTPases are required for activation of Jak/STAT signaling by G protein-coupled receptors. 2003 Feb 1
20 12417261 Differential effect of simvastatin on activation of Rac(1) vs. activation of the heat shock protein 27-mediated pathway upon oxidative stress, in human smooth muscle cells. 2002 Nov 15 1
21 10747906 NADPH oxidase activation increases the sensitivity of intracellular Ca2+ stores to inositol 1,4,5-trisphosphate in human endothelial cells. 2000 May 26 1
22 10386621 Arachidonic acid induces the activation of the stress-activated protein kinase, membrane ruffling and H2O2 production via a small GTPase Rac1. 1999 Jun 11 2
23 9576845 Rac1, and not Rac2, is involved in the regulation of the intracellular hydrogen peroxide level in HepG2 cells. 1998 May 15 1