| 1 |
30919354 | Methods to Investigate the Roles of β-Arrestin-Dependent RalGDS Activation in GPCR-Stimulated Membrane Blebbing. | 2019 |
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| 2 |
28139825 | Attenuated phenotype of Costello syndrome and early death in a patient with an HRAS mutation (c.179G>T; p.Gly60Val) affecting signalling dynamics. | 2017 Sep |
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| 3 |
26687416 | The structure of the Guanine Nucleotide Exchange Factor Rlf in complex with the small G-protein Ral identifies conformational intermediates of the exchange reaction and the basis for the selectivity. | 2016 Feb |
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| 4 |
27149377 | RalGPS2 Is Essential for Survival and Cell Cycle Progression of Lung Cancer Cells Independently of Its Established Substrates Ral GTPases. | 2016 |
2 |
| 5 |
27773821 | Tyrosine phosphorylation of RalGDS by c-Met receptor blocks its interaction with Ras. | 2016 Nov 18 |
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| 6 |
22450745 | Downregulation of Ral GTPase-activating protein promotes tumor invasion and metastasis of bladder cancer. | 2013 Feb 14 |
2 |
| 7 |
23335589 | Functional analysis of a duplication (p.E63_D69dup) in the switch II region of HRAS: new aspects of the molecular pathogenesis underlying Costello syndrome. | 2013 Apr 15 |
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| 8 |
22385209 | Electrostatic effects of mutations of Ras glutamine 61 measured using vibrational spectroscopy of a thiocyanate probe. | 2012 Apr 3 |
2 |
| 9 |
22738401 | Role of electrostatics in differential binding of RalGDS to Rap mutations E30D and K31E investigated by vibrational spectroscopy of thiocyanate probes. | 2012 Aug 9 |
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| 10 |
22982396 | Oncogene Ras/phosphatidylinositol 3-kinase signaling targets histone H3 acetylation at lysine 56. | 2012 Nov 30 |
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| 11 |
23226417 | Identification and characterisation of the RalA-ERp57 interaction: evidence for GDI activity of ERp57. | 2012 |
1 |
| 12 |
21441953 | The human Rgr oncogene is overexpressed in T-cell malignancies and induces transformation by acting as a GEF for Ras and Ral. | 2011 Aug 25 |
1 |
| 13 |
21748802 | Factors determining electrostatic fields in molecular dynamics simulations of the Ras/effector interface. | 2011 Dec |
1 |
| 14 |
20964430 | Vibrational Stark effect spectroscopy at the interface of Ras and Rap1A bound to the Ras binding domain of RalGDS reveals an electrostatic mechanism for protein-protein interaction. | 2010 Nov 25 |
1 |
| 15 |
19567266 | Phylogeny of the CDC25 homology domain reveals rapid differentiation of Ras pathways between early animals and fungi. | 2009 Nov |
1 |
| 16 |
17237388 | The B cell antigen receptor controls AP-1 and NFAT activity through Ras-mediated activation of Ral. | 2007 Feb 1 |
1 |
| 17 |
17462594 | Functional interaction between dopamine receptor subtypes for the regulation of c-fos expression. | 2007 Jun 15 |
1 |
| 18 |
17709381 | Activation of the RalGEF/Ral pathway promotes prostate cancer metastasis to bone. | 2007 Nov |
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| 19 |
17976838 | Rit mutants confirm role of MEK/ERK signaling in neuronal differentiation and reveal novel Par6 interaction. | 2007 Dec |
1 |
| 20 |
16580637 | Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis. | 2006 May 19 |
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| 21 |
17052213 | Regulation of RalA GTPase by phosphatidylinositol 3-kinase as visualized by FRET probes. | 2006 Nov |
1 |
| 22 |
16007223 | The merlin tumor suppressor interacts with Ral guanine nucleotide dissociation stimulator and inhibits its activity. | 2005 Aug 11 |
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| 23 |
15197281 | Electrostatically optimized Ras-binding Ral guanine dissociation stimulator mutants increase the rate of association by stabilizing the encounter complex. | 2004 Jun 22 |
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| 24 |
15313192 | Nitric oxide activates Rap1 and Ral in a Ras-independent manner. | 2004 Sep 10 |
3 |
| 25 |
15470141 | Ral and phospholipase D2-dependent pathway for constitutive metabotropic glutamate receptor endocytosis. | 2004 Oct 6 |
1 |
| 26 |
12624092 | Structure of the GTPase-binding domain of Sec5 and elucidation of its Ral binding site. | 2003 May 9 |
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| 27 |
12168089 | Modulation of phospholipase D by Ras proteins mediated by its effectors Ral-GDS, PI3K and Raf-1. | 2002 Sep |
2 |
| 28 |
11283245 | Regulation of Ras signaling specificity by protein kinase C. | 2001 Apr |
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| 29 |
11292826 | Thermodynamics of Ras/effector and Cdc42/effector interactions probed by isothermal titration calorimetry. | 2001 Jun 29 |
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| 30 |
11340168 | Activation of the Ral and phosphatidylinositol 3' kinase signaling pathways by the ras-related protein TC21. | 2001 Jun |
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| 31 |
10747847 | Identification and characterization of a new family of guanine nucleotide exchange factors for the ras-related GTPase Ral. | 2000 May 5 |
2 |
| 32 |
10869344 | A novel RalGEF-like protein, RGL3, as a candidate effector for rit and Ras. | 2000 Sep 1 |
2 |
| 33 |
11027278 | Ral GTPases contribute to regulation of cyclin D1 through activation of NF-kappaB. | 2000 Nov |
2 |
| 34 |
11455956 | Structure characterization of human RalGDS gene, and the identification of its novel variant. | 2000 |
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| 35 |
10072355 | Ras caught in another affair: the exchange factors for Ral. | 1999 Feb |
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| 36 |
10213614 | Double-mutant analysis of the interaction of Ras with the Ras-binding domain of RGL. | 1999 Apr 20 |
1 |
| 37 |
10364219 | Effector recognition by the small GTP-binding proteins Ras and Ral. | 1999 Jun 18 |
3 |
| 38 |
9550702 | Ras-dependent activation of the small GTPase Ral. | 1998 Apr 9 |
3 |
| 39 |
9566869 | Activation of the small GTPase Ral in platelets. | 1998 May |
1 |
| 40 |
9628477 | Structural basis for the interaction of Ras with RalGDS. | 1998 Jun |
1 |
| 41 |
9843482 | All in the family? New insights and questions regarding interconnectivity of Ras, Rap1 and Ral. | 1998 Dec 1 |
1 |
| 42 |
9931431 | Identification of Ce-AF-6, a novel Caenorhabditis elegans protein, as a putative Ras effector. | 1998 Dec 11 |
1 |
| 43 |
9253406 | Three-dimensional structure of the Ras-interacting domain of RalGDS. | 1997 Aug |
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| 44 |
8636102 | Differential interaction of the ras family GTP-binding proteins H-Ras, Rap1A, and R-Ras with the putative effector molecules Raf kinase and Ral-guanine nucleotide exchange factor. | 1996 Mar 22 |
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| 45 |
15299618 | Crystallization and preliminary crystallographic analysis of the Ras binding domain of RalGDS, a guanine nucleotide dissociation stimulator of the Ral protein. | 1996 Sep 1 |
2 |
| 46 |
7972015 | Activated Ras interacts with the Ral guanine nucleotide dissociation stimulator. | 1994 Nov 8 |
3 |
| 47 |
8094051 | Characterization of a guanine nucleotide dissociation stimulator for a ras-related GTPase. | 1993 Jan |
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| 48 |
2108160 | Guanine nucleotide binding properties of the mammalian RalA protein produced in Escherichia coli. | 1990 Apr 15 |
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