Niacin

hydroxycarboxylic acid receptor 2 ; Mus musculus







32 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35320002 The niacin receptor HCAR2 modulates microglial response and limits disease progression in a mouse model of Alzheimer's disease. 2022 Mar 23 5
2 33605454 Do dimethyl fumarate and nicotinic acid elicit common, potentially HCA2 -mediated adverse reactions? A combined epidemiological-experimental approach. 2021 Oct 3
3 33924461 The Role of GPR109a Signaling in Niacin Induced Effects on Fed and Fasted Hepatic Metabolism. 2021 Apr 13 5
4 34803497 GPR109A alleviate mastitis and enhances the blood milk barrier by activating AMPK/Nrf2 and autophagy. 2021 2
5 31710686 Niacin protects against abdominal aortic aneurysm formation via GPR109A independent mechanisms: role of NAD+/nicotinamide. 2020 Dec 1 4
6 31846627 Discovery of a novel niacin-lipoic acid dimer N2L attenuating atherosclerosis and dyslipidemia with non-flushing effects. 2020 Feb 5 1
7 31858105 Niacin Ameliorates Hepatic Steatosis by Inhibiting De Novo Lipogenesis Via a GPR109A-Mediated PKC-ERK1/2-AMPK Signaling Pathway in C57BL/6 Mice Fed a High-Fat Diet. 2020 Apr 1 2
8 32030468 Niacin-mediated rejuvenation of macrophage/microglia enhances remyelination of the aging central nervous system. 2020 May 1
9 30596513 Niacin fine-tunes energy homeostasis through canonical GPR109A signaling. 2019 Apr 4
10 30625381 Deficiency of metabolite sensing receptor HCA2 impairs the salutary effect of niacin in hemorrhagic shock. 2019 Mar 1 1
11 31540057 Niacin Ameliorates Neuro-Inflammation in Parkinson's Disease via GPR109A. 2019 Sep 14 6
12 31745228 Nicotinic acid promotes sleep through prostaglandin synthesis in mice. 2019 Nov 19 2
13 29514953 Gpr109a Limits Microbiota-Induced IL-23 Production To Constrain ILC3-Mediated Colonic Inflammation. 2018 Apr 15 2
14 29627390 Sodium Butyrate Inhibits Inflammation and Maintains Epithelium Barrier Integrity in a TNBS-induced Inflammatory Bowel Disease Mice Model. 2018 Apr 2
15 29263047 Nicotinic Acid Receptor GPR109A Exerts Anti-Inflammatory Effects Through Inhibiting the Akt/mTOR Signaling Pathway in MIN6 Pancreatic β cells. 2017 Nov 1
16 27570060 Niacin receptor GPR109A inhibits insulin secretion and is down-regulated in type 2 diabetic islet beta-cells. 2016 Oct 1 1
17 26116596 GPR109A Expression in the Murine Min6 Pancreatic Beta Cell Line, and Its Relation with Glucose Metabolism and Inflammation. 2015 Spring 1
18 24412617 Activation of Gpr109a, receptor for niacin and the commensal metabolite butyrate, suppresses colonic inflammation and carcinogenesis. 2014 Jan 16 2
19 24845831 The β-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages. 2014 May 21 4
20 21798616 Niacin inhibits skin dendritic cell mobilization in a GPR109A independent manner but has no impact on monocyte trafficking in atherosclerosis. 2012 May 2
21 22427566 GPR109A as an anti-inflammatory receptor in retinal pigment epithelial cells and its relevance to diabetic retinopathy. 2012 Apr 24 2
22 22434674 3,5-Dihydroxybenzoic acid, a specific agonist for hydroxycarboxylic acid 1, inhibits lipolysis in adipocytes. 2012 Jun 1
23 21317532 Nicotinic acid inhibits progression of atherosclerosis in mice through its receptor GPR109A expressed by immune cells. 2011 Mar 4
24 21774590 High dietary niacin may increase prostaglandin formation but does not increase tumor formation in ApcMin/+ mice. 2011 1
25 20655299 Modulation of HDL metabolism by the niacin receptor GPR109A in mouse hepatocytes. 2010 Nov 1 3
26 20664170 Nicotinic acid- and monomethyl fumarate-induced flushing involves GPR109A expressed by keratinocytes and COX-2-dependent prostanoid formation in mice. 2010 Aug 5
27 19136666 Phenolic acids suppress adipocyte lipolysis via activation of the nicotinic acid receptor GPR109A (HM74a/PUMA-G). 2009 May 1
28 19141678 Niacin stimulates adiponectin secretion through the GPR109A receptor. 2009 Mar 2
29 19276343 GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon. 2009 Apr 1 2
30 19349687 beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice. 2009 May 1
31 17620858 Niacin in cardiovascular prevention: mechanisms, efficacy, and safety. 2007 Aug 1
32 16322797 GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing. 2005 Dec 3