| 1 |
33888607 | SCA7 Mouse Cerebellar Pathology Reveals Preferential Downregulation of Key Purkinje Cell-Identity Genes and Shared Disease Signature with SCA1 and SCA2. | 2021 Jun 2 |
4 |
| 2 |
34852229 | Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7. | 2021 Nov 30 |
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| 3 |
30559154 | SUMOylation by SUMO2 is implicated in the degradation of misfolded ataxin-7 via RNF4 in SCA7 models. | 2019 Jan 11 |
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| 4 |
30625334 | Cell Death Mechanisms in a Mouse Model of Retinal Degeneration in Spinocerebellar Ataxia 7. | 2019 Feb 21 |
9 |
| 5 |
30381411 | Antisense oligonucleotides targeting mutant Ataxin-7 restore visual function in a mouse model of spinocerebellar ataxia type 7. | 2018 Oct 31 |
3 |
| 6 |
25755283 | Poly(Q) Expansions in ATXN7 Affect Solubility but Not Activity of the SAGA Deubiquitinating Module. | 2015 May |
7 |
| 7 |
25859008 | Proteolytic cleavage of ataxin-7 promotes SCA7 retinal degeneration and neurological dysfunction. | 2015 Jul 15 |
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| 8 |
24859968 | The autophagy/lysosome pathway is impaired in SCA7 patients and SCA7 knock-in mice. | 2014 Nov |
3 |
| 9 |
24930601 | Nonallele specific silencing of ataxin-7 improves disease phenotypes in a mouse model of SCA7. | 2014 Sep |
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| 10 |
23197655 | Reduction of mutant ataxin-7 expression restores motor function and prevents cerebellar synaptic reorganization in a conditional mouse model of SCA7. | 2013 Mar 1 |
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| 11 |
23347954 | H1152 promotes the degradation of polyglutamine-expanded ataxin-3 or ataxin-7 independently of its ROCK-inhibiting effect and ameliorates mutant ataxin-3-induced neurodegeneration in the SCA3 transgenic mouse. | 2013 Jul |
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| 12 |
24160175 | Histone deacetylase-3 interacts with ataxin-7 and is altered in a spinocerebellar ataxia type 7 mouse model. | 2013 Oct 27 |
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| 13 |
21827908 | Spinocerebellar ataxia type 7. | 2012 |
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| 14 |
22002997 | Gcn5 loss-of-function accelerates cerebellar and retinal degeneration in a SCA7 mouse model. | 2012 Jan 15 |
4 |
| 15 |
21689595 | CTCF regulates ataxin-7 expression through promotion of a convergently transcribed, antisense noncoding RNA. | 2011 Jun 23 |
3 |
| 16 |
21970987 | The linker histone H1C contributes to the SCA7 nuclear phenotype. | 2011 Sep-Oct |
3 |
| 17 |
22072678 | Spinocerebellar ataxia type 7 cerebellar disease requires the coordinated action of mutant ataxin-7 in neurons and glia, and displays non-cell-autonomous bergmann glia degeneration. | 2011 Nov 9 |
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| 18 |
19909779 | Polyglutamine-expanded ataxin-7 causes cerebellar dysfunction by inducing transcriptional dysregulation. | 2010 Jan |
5 |
| 19 |
20104018 | Autophagy: polyQ toxic fragment turnover. | 2010 Feb |
5 |
| 20 |
20546728 | Polyglutamine-expanded ataxin-7 upregulates Bax expression by activating p53 in cerebellar and inferior olivary neurons. | 2010 Aug |
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| 21 |
20600911 | Polyglutamine toxicity induces rod photoreceptor division, morphological transformation or death in spinocerebellar ataxia 7 mouse retina. | 2010 Oct |
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| 22 |
17646170 | Proteolytic cleavage of ataxin-7 by caspase-7 modulates cellular toxicity and transcriptional dysregulation. | 2007 Oct 12 |
10 |
| 23 |
18054568 | Visceral neuropathy and intestinal pseudo-obstruction in a murine model of a nuclear inclusion disease. | 2007 Dec |
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| 24 |
16434483 | Polyglutamine expansion causes neurodegeneration by altering the neuronal differentiation program. | 2006 Mar 1 |
4 |
| 25 |
16494529 | Glutamine-expanded ataxin-7 alters TFTC/STAGA recruitment and chromatin structure leading to photoreceptor dysfunction. | 2006 Mar |
7 |
| 26 |
16936724 | Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport. | 2006 Oct |
1 |
| 27 |
15932940 | Polyglutamine-expanded ataxin-7 inhibits STAGA histone acetyltransferase activity to produce retinal degeneration. | 2005 Jun 14 |
3 |
| 28 |
16297465 | Identification and characterization of Spinocerebellar Ataxia Type 7 (SCA7) isoform SCA7b in mice. | 2005 Dec 20 |
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| 29 |
14985428 | Disease progression despite early loss of polyglutamine protein expression in SCA7 mouse model. | 2004 Feb 25 |
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| 30 |
15494410 | Hsp70 and Hsp40 chaperones do not modulate retinal phenotype in SCA7 mice. | 2004 Dec 31 |
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| 31 |
14526177 | Insights into the molecular basis of polyglutamine neurodegeneration from studies of a spinocerebellar ataxia type 7 mouse model. | 2003 |
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| 32 |
12039035 | Cloning and expression analysis of the murine homolog of the spinocerebellar ataxia type 7 (SCA7) gene. | 2002 Feb 20 |
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| 33 |
12077187 | Polyglutamine-expanded ataxin-7 promotes non-cell-autonomous purkinje cell degeneration and displays proteolytic cleavage in ataxic transgenic mice. | 2002 Jun 15 |
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| 34 |
12471061 | Progressive retinal degeneration and dysfunction in R6 Huntington's disease mice. | 2002 Dec 15 |
4 |
| 35 |
11487572 | SCA7 mouse models show selective stabilization of mutant ataxin-7 and similar cellular responses in different neuronal cell types. | 2001 Aug 1 |
2 |
| 36 |
11580893 | Polyglutamine-expanded ataxin-7 antagonizes CRX function and induces cone-rod dystrophy in a mouse model of SCA7. | 2001 Sep 27 |
3 |
| 37 |
11030754 | Expanded polyglutamines induce neurodegeneration and trans-neuronal alterations in cerebellum and retina of SCA7 transgenic mice. | 2000 Oct 12 |
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