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35432890 | Photo-Brook rearrangement of acyl silanes as a strategy for photoaffinity probe design. | 2022 Mar 30 |
1 |
| 2 |
33669763 | In Silico Strategy for Targeting the mTOR Kinase at Rapamycin Binding Site by Small Molecules. | 2021 Feb 19 |
2 |
| 3 |
34542533 | A New Toolkit for Evaluating Gene Functions using Conditional Cas9 Stabilization. | 2021 Sep 2 |
2 |
| 4 |
32622856 | FK506 binding proteins and inflammation related signalling pathways; basic biology, current status and future prospects for pharmacological intervention. | 2020 Nov |
2 |
| 5 |
33195437 | Interactions of FK506 and Rapamycin With FK506 Binding Protein 12 in Opportunistic Human Fungal Pathogens. | 2020 |
5 |
| 6 |
30877063 | Properties of FDA-approved small molecule protein kinase inhibitors. | 2019 Jun |
1 |
| 7 |
31309829 | A Binding Site Hotspot Map of the FKBP12-Rapamycin-FRB Ternary Complex by Photoaffinity Labeling and Mass Spectrometry-Based Proteomics. | 2019 Jul 31 |
1 |
| 8 |
31548690 | A modular DNA scaffold to study protein-protein interactions at single-molecule resolution. | 2019 Oct |
1 |
| 9 |
31807738 | Ligand-activated BRET9 imaging for measuring protein-protein interactions in living mice. | 2019 Dec 19 |
1 |
| 10 |
28752574 | Improved sensitivity of firefly luminescent intermediate-based protein interaction assay using Ser 440 mutant with lower adenylation activity. | 2018 Feb |
1 |
| 11 |
25822756 | A signal-on fluorosensor based on quench-release principle for sensitive detection of antibiotic rapamycin. | 2015 Mar 26 |
1 |
| 12 |
25986568 | FK506-Binding Proteins and Their Diverse Functions. | 2015 |
1 |
| 13 |
26561008 | Differential Large-Amplitude Breathing Motions in the Interface of FKBP12-Drug Complexes. | 2015 Dec 1 |
1 |
| 14 |
24846380 | Bioluminescence resonance energy transfer system for measuring dynamic protein-protein interactions in bacteria. | 2014 May 20 |
4 |
| 15 |
23224428 | Functional diversity and pharmacological profiles of the FKBPs and their complexes with small natural ligands. | 2013 Sep |
1 |
| 16 |
23989449 | ScFKBP12 bridges rapamycin and AtTOR in Arabidopsis. | 2013 Nov |
1 |
| 17 |
19925836 | Lesion complexity determines arterial drug distribution after local drug delivery. | 2010 Mar 19 |
1 |
| 18 |
21182472 | FK506 binding proteins as targets in anticancer therapy. | 2010 Nov 1 |
1 |
| 19 |
17350953 | The rapamycin-binding domain of the protein kinase mammalian target of rapamycin is a destabilizing domain. | 2007 May 4 |
1 |
| 20 |
17531780 | Sirolimus as part of immunosuppressive therapy for refractory chronic graft-versus-host disease. | 2007 Jun |
2 |
| 21 |
16490780 | Establishment of a cell model based on FKBP12 dimerization for screening of FK506-like neurotrophic small molecular compounds. | 2006 Apr |
1 |
| 22 |
15783192 | Design of an intein that can be inhibited with a small molecule ligand. | 2005 Mar 30 |
1 |
| 23 |
15796538 | Characterization of the FKBP.rapamycin.FRB ternary complex. | 2005 Apr 6 |
1 |
| 24 |
16103094 | Novel fusion protein approach for efficient high-throughput screening of small molecule-mediating protein-protein interactions in cells and living animals. | 2005 Aug 15 |
2 |
| 25 |
9334222 | Regulation of eIF-4E BP1 phosphorylation by mTOR. | 1997 Oct 17 |
2 |
| 26 |
9396011 | Neural roles of immunophilins and their ligands. | 1997 Oct |
2 |
| 27 |
8662507 | Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP. | 1996 Jul 12 |
1 |
| 28 |
8785272 | Tryptophan dynamics of the FK506 binding protein: time-resolved fluorescence and simulations. | 1996 Mar |
1 |
| 29 |
8955134 | FAP48, a new protein that forms specific complexes with both immunophilins FKBP59 and FKBP12. Prevention by the immunosuppressant drugs FK506 and rapamycin. | 1996 Dec 20 |
1 |
| 30 |
9005438 | FK506-binding protein mutational analysis: defining the active-site residue contributions to catalysis and the stability of ligand complexes. | 1996 Feb |
2 |
| 31 |
21232286 | Expression and regulation of ryanodine receptor/calcium release channels. | 1996 May |
1 |
| 32 |
7531689 | Characterization of an exchange reaction between soluble FKBP-12 and the FKBP.ryanodine receptor complex. Modulation by FKBP mutants deficient in peptidyl-prolyl isomerase activity. | 1995 Feb 10 |
2 |
| 33 |
7533090 | FK506 binding protein 12 mediates sensitivity to both FK506 and rapamycin in murine mast cells. | 1995 Feb |
3 |
| 34 |
7566123 | Control of p70 s6 kinase by kinase activity of FRAP in vivo. | 1995 Oct 5 |
1 |
| 35 |
7642551 | FK506 binding protein mutational analysis. Defining the surface residue contributions to stability of the calcineurin co-complex. | 1995 Aug 11 |
3 |
| 36 |
8521476 | Calcineurin associated with the inositol 1,4,5-trisphosphate receptor-FKBP12 complex modulates Ca2+ flux. | 1995 Nov 3 |
2 |
| 37 |
15299838 | Comparative X-ray structures of the major binding protein for the immunosuppressant FK506 (tacrolimus) in unliganded form and in complex with FK506 and rapamycin. | 1995 Jul 1 |
4 |
| 38 |
7521160 | A putative sirolimus (rapamycin) effector protein. | 1994 Aug 30 |
2 |
| 39 |
1375751 | Heat capacity changes and hydrophobic interactions in the binding of FK506 and rapamycin to the FK506 binding protein. | 1992 Jun 1 |
2 |
| 40 |
1716149 | Exon organization of the human FKBP-12 gene: correlation with structural and functional protein domains. | 1991 Sep 3 |
1 |