lysophosphatidic acid

mitogen-activated protein kinase 1 ; Homo sapiens







58 Article(s)
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1 35391830 Single-cell RNA sequencing identifies a migratory keratinocyte subpopulation expressing THBS1 in epidermal wound healing. 2022 Apr 15 1
2 32007501 Antidepressants induce profibrotic responses via the lysophosphatidic acid receptor LPA1. 2020 Apr 15 1
3 30403494 Lysophosphatidic acid represses autophagy in prostate carcinoma cells. 2019 Aug 1
4 31781264 Berberine Modulates LPA Function to Inhibit the Proliferation and Inflammation of FLS-RA via p38/ERK MAPK Pathway Mediated by LPA1. 2019 5
5 29328374 ATX‑LPA axis facilitates estrogen‑induced endometrial cancer cell proliferation via MAPK/ERK signaling pathway. 2018 Mar 4
6 28348459 Lysophosphatidic Acid Triggers Apoptosis in HeLa Cells through the Upregulation of Tumor Necrosis Factor Receptor Superfamily Member 21. 2017 2
7 28943105 A549 cells as a model to study endogenous LPA1 receptor signaling and regulation. 2017 Nov 15 1
8 29209219 Differential Effects of Inhibitor Combinations on Lysophosphatidic Acid-Mediated Chemokine Secretion in Unprimed and Tumor Necrosis Factor-α-Primed Synovial Fibroblasts. 2017 3
9 25491146 Omega-3 fatty acids and other FFA4 agonists inhibit growth factor signaling in human prostate cancer cells. 2015 Feb 1
10 26171059 Type II cyclic guanosine monophosphate-dependent protein kinase inhibits Rac1 activation in gastric cancer cells. 2015 Jul 4
11 26553339 Lysophosphatidic acid enhances survival of human CD34(+) cells in ischemic conditions. 2015 Nov 10 1
12 24461407 Lysophosphatidic acid rescues human dental pulp cells from ischemia-induced apoptosis. 2014 Feb 2
13 24845645 Cyclic phosphatidic acid and lysophosphatidic acid induce hyaluronic acid synthesis via CREB transcription factor regulation in human skin fibroblasts. 2014 Sep 2
14 25424429 Convergent regulation of neuronal differentiation and Erk and Akt kinases in human neural progenitor cells by lysophosphatidic acid, sphingosine 1-phosphate, and LIF: specific roles for the LPA1 receptor. 2014 1
15 23319595 The MLK-related kinase (MRK) is a novel RhoC effector that mediates lysophosphatidic acid (LPA)-stimulated tumor cell invasion. 2013 Feb 22 2
16 23618389 The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells. 2013 Apr 24 1
17 23747852 Regulation of angiogenesis by phospholipid lysophosphatidic acid. 2013 Jun 1 1
18 23942151 TAZ mediates lysophosphatidic acid-induced migration and proliferation of epithelial ovarian cancer cells. 2013 5
19 22577133 Lysophosphatidic acid induces early growth response-1 (Egr-1) protein expression via protein kinase Cδ-regulated extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) activation in vascular smooth muscle cells. 2012 Jun 29 5
20 22847216 Involvement of the cAMP response element binding protein, CREB, and cyclin D1 in LPA-induced proliferation of P19 embryonic carcinoma cells. 2012 Sep 1
21 22024689 MicroRNA-30c-2* expressed in ovarian cancer cells suppresses growth factor-induced cellular proliferation and downregulates the oncogene BCL9. 2011 Dec 2
22 20177148 Ovarian cancer-derived lysophosphatidic acid stimulates secretion of VEGF and stromal cell-derived factor-1 alpha from human mesenchymal stem cells. 2010 Apr 30 2
23 20533299 LPA rescues ER stress-associated apoptosis in hypoxia and serum deprivation-stimulated mesenchymal stem cells. 2010 Nov 1 8
24 20934509 Reactive oxygen species mediate lysophosphatidic acid induced signaling in ovarian cancer cells. 2010 Dec 15 1
25 21209852 Lysophosphatidic acid induces MDA-MB-231 breast cancer cells migration through activation of PI3K/PAK1/ERK signaling. 2010 Dec 30 10
26 18658095 ERK1/2 mediate wounding- and G-protein-coupled receptor ligands-induced EGFR activation via regulating ADAM17 and HB-EGF shedding. 2009 Jan 1
27 18027882 Lysophosphatidic acid in malignant ascites stimulates migration of human mesenchymal stem cells. 2008 May 15 2
28 18268018 Calcium-mediated interactions regulate the subcellular localization of extracellular signal-regulated kinases. 2008 Apr 25 1
29 18309089 Lysophosphatidic acid induces rapid and sustained decreases in epidermal growth factor receptor binding via different signaling pathways in BEAS-2B airway epithelial cells. 2008 Jun 1
30 18762583 ERK regulates Golgi and centrosome orientation towards the leading edge through GRASP65. 2008 Sep 8 2
31 19116446 Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells. 2008 Dec 31 1
32 17251460 Lysophosphatidic acid promoting corneal epithelial wound healing by transactivation of epidermal growth factor receptor. 2007 Feb 5
33 17531530 Lysophosphatidic acid induces prostate cancer PC3 cell migration via activation of LPA(1), p42 and p38alpha. 2007 Jul 5
34 17937769 Lysophosphatidic acid inhibits ghrelin secretion in the human gastric adenocarcinoma AGS cell line: role of mitogenic activated protein kinase signaling pathway. 2007 Nov 1
35 16197369 Transcriptional regulation of lysophosphatidic acid-induced interleukin-8 expression and secretion by p38 MAPK and JNK in human bronchial epithelial cells. 2006 Feb 1 13
36 16760261 Lysophosphatidic acid as a mediator for proinflammatory agonists in a human corneal epithelial cell line. 2006 Nov 3
37 15653692 Signaling mechanisms responsible for lysophosphatidic acid-induced urokinase plasminogen activator expression in ovarian cancer cells. 2005 Mar 18 2
38 15710431 Lysophosphatidic acid inhibits anti-Fas-mediated apoptosis enhanced by actin depolymerization in epithelial ovarian cancer. 2005 Feb 14 3
39 16210650 IL-4 regulates MEK expression required for lysophosphatidic acid-mediated chemokine generation by human mast cells. 2005 Oct 15 1
40 16230405 Lysophosphatidic acid acyltransferase-beta is a prognostic marker and therapeutic target in gynecologic malignancies. 2005 Oct 15 1
41 15024019 Interleukin 6 mediates the lysophosphatidic acid-regulated cross-talk between stromal and epithelial prostate cancer cells. 2004 May 14 3
42 15118098 Modular construction of a signaling scaffold: MORG1 interacts with components of the ERK cascade and links ERK signaling to specific agonists. 2004 May 4 1
43 15194005 Stimulation of early gene induction and cell proliferation by lysophosphatidic acid in human amnion-derived WISH cells: role of phospholipase D-mediated pathway. 2004 Jul 15 3
44 15533756 Lysophosphatidic acid inhibits TGF-beta-mediated stimulation of type I collagen mRNA stability via an ERK-dependent pathway in dermal fibroblasts. 2004 Oct 3
45 12730329 Lysophosphatidic acid signals through mitogen-activated protein kinase-extracellular signal regulated kinase in ovarian theca cells expressing the LPA1/edg2-receptor: involvement of a nonclassical pathway? 2003 Aug 2
46 12765417 Transcription factor activation and mitogenic synergism in airway smooth muscle cells. 2003 May 2
47 12902401 Mechanisms in LPA-induced tumor cell migration: critical role of phosphorylated ERK. 2003 Sep 15 7
48 14504178 Vascular remodeling induced by naturally occurring unsaturated lysophosphatidic acid in vivo. 2003 Oct 7 1
49 14723340 Lysophosphatidic acid inhibits melanocyte proliferation via cell cycle arrest. 2003 Dec 3
50 11832770 Guanosine phosphate binding protein coupled receptors in prostate cancer: a review. 2002 Mar 3