Serine

mitogen-activated protein kinase 1 ; Homo sapiens







284 Article(s)
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101 23017243 Novel involvement of leukotriene B₄ receptor 2 through ERK activation by PP2A down-regulation in leukotriene B₄-induced keratin phosphorylation and reorganization of pancreatic cancer cells. 2012 Dec 1
102 23178880 ERK1/2-dependent phosphorylation and nuclear translocation of PKM2 promotes the Warburg effect. 2012 Dec 1
103 20015194 A novel pathway for receptor-mediated post-translational activation of inducible nitric oxide synthase. 2011 Feb 2
104 21148411 Role of integrins in angiotensin II-induced proliferation of vascular smooth muscle cells. 2011 Mar 1
105 21187384 Phosphorylation of Grainy head by ERK is essential for wound-dependent regeneration but not for development of an epidermal barrier. 2011 Jan 11 1
106 21285457 Crystallographic and mutational analysis of the CD40-CD154 complex and its implications for receptor activation. 2011 Apr 1 1
107 21392397 Impact of oncogenic K-RAS on YB-1 phosphorylation induced by ionizing radiation. 2011 Mar 10 1
108 21730285 Nuclear extracellular signal-regulated kinase 1 and 2 translocation is mediated by casein kinase 2 and accelerated by autophosphorylation. 2011 Sep 1
109 21908610 Phosphorylation of the kinase interaction motif in mitogen-activated protein (MAP) kinase phosphatase-4 mediates cross-talk between protein kinase A and MAP kinase signaling pathways. 2011 Nov 4 1
110 22033920 Mitogen-activated protein kinase extracellular signal-regulated kinase 2 phosphorylates and promotes Pin1 protein-dependent promyelocytic leukemia protein turnover. 2011 Dec 30 2
111 22292133 Mechanism of RAF isoform switching induced by oncogenic RAS in melanoma. 2011 Sep 2
112 19464346 Participation of signaling pathways in the derepression of luteinizing hormone receptor transcription. 2010 Jan 27 1
113 20015475 Prostaglandin E2 activates cAMP response element-binding protein in glioma cells via a signaling pathway involving PKA-dependent inhibition of ERK. 2010 Feb 1
114 20101459 The role of MAPK-ERK pathway in 67-kDa laminin receptor-induced FasL expression in human cholangiocarcinoma cells. 2010 Oct 1
115 20122898 MKP-7, a JNK phosphatase, blocks ERK-dependent gene activation by anchoring phosphorylated ERK in the cytoplasm. 2010 Mar 5 1
116 20160123 Prostaglandin F2alpha represses IGF-I-stimulated IRS1/phosphatidylinositol-3-kinase/AKT signaling in the corpus luteum: role of ERK and P70 ribosomal S6 kinase. 2010 Mar 2
117 20178980 cAMP/CREB-mediated transcriptional regulation of ectonucleoside triphosphate diphosphohydrolase 1 (CD39) expression. 2010 May 7 1
118 20361728 Phosphorylation of the transcription factor Ets-1 by ERK2: rapid dissociation of ADP and phospho-Ets-1. 2010 May 4 1
119 20459645 Osteopontin selectively regulates p70S6K/mTOR phosphorylation leading to NF-kappaB dependent AP-1-mediated ICAM-1 expression in breast cancer cells. 2010 May 7 1
120 20675591 ERK is integral to the IFN-γ-mediated activation of STAT1, the expression of key genes implicated in atherosclerosis, and the uptake of modified lipoproteins by human macrophages. 2010 Sep 1 1
121 20729206 m-Calpain activation is regulated by its membrane localization and by its binding to phosphatidylinositol 4,5-bisphosphate. 2010 Oct 22 1
122 21102438 AKAP-Lbc enhances cyclic AMP control of the ERK1/2 cascade. 2010 Dec 1
123 18658095 ERK1/2 mediate wounding- and G-protein-coupled receptor ligands-induced EGFR activation via regulating ADAM17 and HB-EGF shedding. 2009 Jan 1
124 19109187 Toll-like receptor-mediated production of IL-1Ra is negatively regulated by GSK3 via the MAPK ERK1/2. 2009 Jan 1 1
125 19153083 MEK1 binds directly to betaarrestin1, influencing both its phosphorylation by ERK and the timing of its isoprenaline-stimulated internalization. 2009 Apr 24 1
126 19274665 Soluble factors derived from stroma activated androgen receptor phosphorylation in human prostate LNCaP cells: roles of ERK/MAP kinase. 2009 Jun 15 2
127 19361221 How mitogen-activated protein kinases recognize and phosphorylate their targets: A QM/MM study. 2009 May 6 1
128 19401382 TLR2 ligands augment cPLA2alpha activity and lead to enhanced leukotriene release in human monocytes. 2009 Aug 1
129 19405034 RNF2 is the target for phosphorylation by the p38 MAPK and ERK signaling pathways. 2009 May 1
130 19429262 NADPH oxidase and ERK1/2 are involved in cadmium induced-STAT3 activation in HepG2 cells. 2009 Jun 22 1
131 19447520 Protein kinase SGK1 enhances MEK/ERK complex formation through the phosphorylation of ERK2: implication for the positive regulatory role of SGK1 on the ERK function during liver regeneration. 2009 Jul 3
132 19623651 Prostaglandin E(2) promotes cell proliferation via protein kinase C/extracellular signal regulated kinase pathway-dependent induction of c-Myc expression in human esophageal squamous cell carcinoma cells. 2009 Dec 1 2
133 19687304 TAK1-mediated serine/threonine phosphorylation of epidermal growth factor receptor via p38/extracellular signal-regulated kinase: NF-{kappa}B-independent survival pathways in tumor necrosis factor alpha signaling. 2009 Oct 2
134 19801668 Identification and functional characterization of ERK/MAPK phosphorylation sites in the Runx2 transcription factor. 2009 Nov 20 3
135 19885032 Extracellular Signal-regulated Kinase Activation Is Required for Serine 727 Phosphorylation of STAT3 in Schwann Cells in vitro and in vivo. 2009 Jun 7
136 20087429 Erk signaling and chromatin remodeling in MMTV promoter activation by progestins. 2009 Oct 2 1
137 18084034 ERK is a novel regulatory kinase for poly(A) polymerase. 2008 Feb 2
138 18204781 Phosphorylation and nuclear translocation of STAT3 regulated by the Epstein-Barr virus latent membrane protein 1 in nasopharyngeal carcinoma. 2008 Feb 2
139 18245089 Mitogen-activated protein kinase ERK1/2 regulates the class II transactivator. 2008 Apr 4 2
140 18258304 Rac mediates TNF-induced cytokine production via modulation of NF-kappaB. 2008 May 1
141 18372343 Protein kinase Calpha-induced derepression of the human luteinizing hormone receptor gene transcription through ERK-mediated release of HDAC1/Sin3A repressor complex from Sp1 sites. 2008 Jun 1
142 18372406 Phosphorylation at serines 104 and 106 by Erk1/2 MAPK is important for estrogen receptor-alpha activity. 2008 Apr 1
143 18378670 ERK and the F-box protein betaTRCP target STAT1 for degradation. 2008 Jun 6 1
144 18417338 Convergence on chromatin of non-genomic and genomic pathways of hormone signaling. 2008 Apr 1
145 18454176 Oncogenic Ras upregulates NADPH oxidase 1 gene expression through MEK-ERK-dependent phosphorylation of GATA-6. 2008 Aug 21 1
146 18476811 Phosphorylation of Argonaute 2 at serine-387 facilitates its localization to processing bodies. 2008 Aug 1 4
147 18487214 Epidermal growth factor-stimulated extravillous cytotrophoblast motility is mediated by the activation of PI3-K, Akt and both p38 and p42/44 mitogen-activated protein kinases. 2008 Aug 1
148 18596912 PPARgamma and MEK Interactions in Cancer. 2008 1
149 18632853 ERK1/2-mediated phosphorylation of small hepatitis delta antigen at serine 177 enhances hepatitis delta virus antigenomic RNA replication. 2008 Oct 1
150 18694962 Serum-induced phosphorylation of the serum response factor coactivator MKL1 by the extracellular signal-regulated kinase 1/2 pathway inhibits its nuclear localization. 2008 Oct 1