Serine

mitogen-activated protein kinase 1 ; Homo sapiens







284 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
51 27339895 Role of WW Domain-containing Oxidoreductase WWOX in Driving T Cell Acute Lymphoblastic Leukemia Maturation. 2016 Aug 12 1
52 27793200 Subcellular localisation of pMEK has a different prognosis in locally advanced head and neck cancer treated with concomitant radiochemotherapy. 2016 Oct 28 1
53 27986870 MEK-ERK-mediated phosphorylation of Mdm2 at Ser-166 in hepatocytes. Mdm2 IS ACTIVATED IN RESPONSE TO INHIBITED Akt SIGNALING. 2016 Dec 16 1
54 28008418 Regulation of Group I Metabotropic Glutamate Receptors by MAPK/ERK in Neurons. 2016 2
55 28076932 Aortic dissection is associated with reduced polycystin-1 expression, an abnormality that leads to increased ERK phosphorylation in vascular smooth muscle cells. 2016 Dec 16 1
56 25391654 Conformational dynamics of the focal adhesion targeting domain control specific functions of focal adhesion kinase in cells. 2015 Jan 2 1
57 25425646 A novel MEK-ERK-AMPK signaling axis controls chemokine receptor CCR7-dependent survival in human mature dendritic cells. 2015 Jan 9 1
58 25658205 Erk2 phosphorylation of Drp1 promotes mitochondrial fission and MAPK-driven tumor growth. 2015 Feb 5 1
59 25701783 Role of tyrosine kinase-independent phosphorylation of EGFR with activating mutation in cisplatin-treated lung cancer cells. 2015 Mar 20 1
60 25826088 Paxillin promotes colorectal tumor invasion and poor patient outcomes via ERK-mediated stabilization of Bcl-2 protein by phosphorylation at Serine 87. 2015 Apr 20 2
61 25908842 RIP1 negatively regulates basal autophagic flux through TFEB to control sensitivity to apoptosis. 2015 Jun 1
62 26054059 Structural and Dynamic Features of F-recruitment Site Driven Substrate Phosphorylation by ERK2. 2015 Jun 8 1
63 26171055 Nitric oxide/cyclic guanosine monophosphate inducers sodium nitroprusside and L-arginine inhibit the proliferation of gastric cancer cells via the activation of type II cyclic guanosine monophosphate-dependent protein kinase. 2015 Jul 2
64 26181363 The class II transactivator (CIITA) is regulated by post-translational modification cross-talk between ERK1/2 phosphorylation, mono-ubiquitination and Lys63 ubiquitination. 2015 Jun 19 1
65 26194464 Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation. 2015 Jul 21 2
66 26245900 The Mutant KRAS Gene Up-regulates BCL-XL Protein via STAT3 to Confer Apoptosis Resistance That Is Reversed by BIM Protein Induction and BCL-XL Antagonism. 2015 Sep 25 1
67 24308965 HSP27 phosphorylation modulates TRAIL-induced activation of Src-Akt/ERK signaling through interaction with β-arrestin2. 2014 Mar 1
68 24498195 ERK MAP kinase activation in spinal cord regulates phosphorylation of Cdk5 at serine 159 and contributes to peripheral inflammation induced pain/hypersensitivity. 2014 1
69 24509437 Phosphorylation of human immunodeficiency virus type 1 capsid protein at serine 16, required for peptidyl-prolyl isomerase-dependent uncoating, is mediated by virion-incorporated extracellular signal-regulated kinase 2. 2014 May 8
70 24520095 Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib in liver cancer cells in vitro and in vivo. 2014 Mar 1 1
71 24525237 Wild-type H- and N-Ras promote mutant K-Ras-driven tumorigenesis by modulating the DNA damage response. 2014 Feb 10 1
72 24626525 Cholera toxin, a typical protein kinase A activator, induces G1 phase growth arrest in human bladder transitional cell carcinoma cells via inhibiting the c-Raf/MEK/ERK signaling pathway. 2014 May 1
73 24681962 Novel function of the chromosome 7 open reading frame 41 gene to promote leukemic megakaryocyte differentiation by modulating TPA-induced signaling. 2014 Mar 28 2
74 25204653 Post-translational regulation of mitogen-activated protein kinase phosphatase (MKP)-1 and MKP-2 in macrophages following lipopolysaccharide stimulation: the role of the C termini of the phosphatases in determining their stability. 2014 Oct 17 1
75 25353341 Phosphorylation of sterol regulatory element-binding protein (SREBP)-1c by p38 kinases, ERK and JNK influences lipid metabolism and the secretome of human liver cell line HepG2. 2014 Dec 1
76 25478290 MUC18 Differentially Regulates Pro-Inflammatory and Anti-Viral Responses in Human Airway Epithelial Cells. 2014 Oct 1
77 22183614 Phospholipase A(2) activation by poultry particulate matter is mediated through extracellular signal-regulated kinase in lung epithelial cells: regulation of interleukin-8 release. 2013 Nov 1
78 23348708 p38 Mitogen-activated protein kinase and extracellular signal-regulated kinase signaling pathways are not essential regulators of formyl peptide-stimulated p47(phox) activation in neutrophils. 2013 Feb 15 1
79 23405013 ERK-mediated phosphorylation of fibroblast growth factor receptor 1 on Ser777 inhibits signaling. 2013 Feb 12 3
80 23426330 The axis of MAPK1/3-XBP1u-FOXO1 controls autophagic dynamics in cancer cells. 2013 May 1
81 23434660 Epidermal growth factor stimulates extracellular-signal regulated kinase phosphorylation of a novel site on cytoplasmic Dynein intermediate chain 2. 2013 Feb 7 1
82 23529931 Endothelial RAF1/ERK activation regulates arterial morphogenesis. 2013 May 9 1
83 23653349 p21-activated kinase 1 (PAK1) can promote ERK activation in a kinase-independent manner. 2013 Jul 5 1
84 23667643 Viral infection increases glucocorticoid-induced interleukin-10 production through ERK-mediated phosphorylation of the glucocorticoid receptor in dendritic cells: potential clinical implications. 2013 2
85 23811561 Erythropoietin prevents hypoxia-induced GATA-4 ubiquitination via phosphorylation of serine 105 of GATA-4. 2013 1
86 23814485 A new p53 target gene, RKIP, is essential for DNA damage-induced cellular senescence and suppression of ERK activation. 2013 Jul 1
87 23822636 Inverse correlation between Thr-669 and constitutive tyrosine phosphorylation in the asymmetric epidermal growth factor receptor dimer conformation. 2013 Oct 1
88 23874979 ERK positive feedback regulates a widespread network of tyrosine phosphorylation sites across canonical T cell signaling and actin cytoskeletal proteins in Jurkat T cells. 2013 1
89 23892079 IRF3 and ERK MAP-kinases control nitric oxide production from macrophages in response to poly-I:C. 2013 Sep 17 1
90 24023871 The HDAC inhibitor LBH589 induces ERK-dependent prometaphase arrest in prostate cancer via HDAC6 inactivation and down-regulation. 2013 2
91 24049075 ERK phosphorylation of MED14 in promoter complexes during mitogen-induced gene activation by Elk-1. 2013 Dec 2
92 24080014 Serine-204 in the linker region of Smad3 mediates the collagen-I response to TGF-β in a cell phenotype-specific manner. 2013 Nov 15 1
93 24312439 The MEK-ERK pathway is necessary for serine phosphorylation of mitochondrial STAT3 and Ras-mediated transformation. 2013 1
94 22258404 ERK2 phosphorylation of serine 77 regulates Bmf pro-apoptotic activity. 2012 Jan 19 2
95 22298426 Phosphorylation of Stim1 at serine 575 via netrin-2/Cdo-activated ERK1/2 is critical for the promyogenic function of Stim1. 2012 Apr 2
96 22370157 Phosphorylation of human estrogen receptor-beta at serine 105 inhibits breast cancer cell migration and invasion. 2012 Jul 6 1
97 22392765 Targeting Mnks for cancer therapy. 2012 Feb 1
98 22586091 Gene regulation via excitation and BDNF is mediated by induction and phosphorylation of the Etv1 transcription factor in cerebellar granule cells. 2012 May 29 2
99 22767595 Cell surface expression of the major amyloid-β peptide (Aβ)-degrading enzyme, neprilysin, depends on phosphorylation by mitogen-activated protein kinase/extracellular signal-regulated kinase kinase (MEK) and dephosphorylation by protein phosphatase 1a. 2012 Aug 24 1
100 22955283 Extracellular signal-regulated kinase 2 (ERK2) mediates phosphorylation and inactivation of nuclear interaction partner of anaplastic lymphoma kinase (NIPA) at G2/M. 2012 Nov 2 2