2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

mitogen-activated protein kinase 1 ; Homo sapiens







1260 Article(s)
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201 25898413 Dihydroaustrasulfone alcohol inhibits PDGF-induced proliferation and migration of human aortic smooth muscle cells through inhibition of the cell cycle. 2015 Apr 17 1
202 25936372 MFG-E8 inhibits neutrophil migration through αvβ₃-integrin-dependent MAP kinase activation. 2015 Jul 1
203 25981695 Iron deficiency upregulates Egr1 expression. 2015 Jul 1
204 25982794 Cinobufagin exerts anti-proliferative and pro-apoptotic effects through the modulation ROS-mediated MAPKs signaling pathway. 2015 Jun 1
205 25983101 ANXA1 silencing increases the sensitivity of cancer cells to low-concentration arsenic trioxide treatment by inhibiting ERK MAPK activation. 2015 Jul-Aug 1
206 26026912 Aflatoxin B1 augments the synthesis of corticotropin releasing hormone in JEG-3 placental cells. 2015 Jul 25 2
207 26059188 Hepatitis B Virus X Protein (HBx) Is Responsible for Resistance to Targeted Therapies in Hepatocellular Carcinoma: Ex Vivo Culture Evidence. 2015 Oct 1 1
208 26086160 Reactive oxygen species mediate nitric oxide production through ERK/JNK MAPK signaling in HAPI microglia after PFOS exposure. 2015 Oct 15 2
209 26096905 Salicin from Willow Bark can Modulate Neurite Outgrowth in Human Neuroblastoma SH-SY5Y Cells. 2015 Oct 1
210 26220523 LK6/Mnk2a is a new kinase of alpha synuclein phosphorylation mediating neurodegeneration. 2015 Jul 29 1
211 26266487 The Interplay of Akt and ERK in Aβ Toxicity and Insulin-Mediated Protection in Primary Hippocampal Cell Culture. 2015 Nov 2
212 26304749 HCRP-1 regulates cell migration and invasion via EGFR-ERK mediated up-regulation of MMP-2 with prognostic significance in human renal cell carcinoma. 2015 Aug 25 4
213 26316083 8-Methoxypsoralen Induces Intrinsic Apoptosis in HepG2 Cells: Involvement of Reactive Oxygen Species Generation and ERK1/2 Pathway Inhibition. 2015 1
214 26347199 A bioinformatic and mechanistic study elicits the antifibrotic effect of ursolic acid through the attenuation of oxidative stress with the involvement of ERK, PI3K/Akt, and p38 MAPK signaling pathways in human hepatic stellate cells and rat liver. 2015 1
215 26357647 Effect of Glucagon-like Peptide-1 on the Differentiation of Adipose-derived Stem Cells into Osteoblasts and Adipocytes. 2015 Aug 2
216 26359088 Widdrol-induced lipolysis is mediated by PKC and MEK/ERK in 3T3-L1 adipocytes. 2015 Dec 2
217 26420479 Interleukin-29 induces receptor activator of NF-κB ligand expression in fibroblast-like synoviocytes via MAPK signaling pathways. 2015 Nov 2
218 26439801 Hydrogen peroxide mediates hyperglycemia-induced invasive activity via ERK and p38 MAPK in human pancreatic cancer. 2015 Oct 13 2
219 26526356 A Her2-let-7-β2-AR circuit affects prognosis in patients with Her2-positive breast cancer. 2015 Nov 2 1
220 26558197 Protein tyrosine phosphatase 1B regulates migration of ARPE-19 cells through EGFR/ERK signaling pathway. 2015 1
221 26696477 [Involvement of MAPK signal transduction pathways in regulating the expression of glucocorticoid receptor isoforms in nasal polyp epithelia in vitro]. 2015 Oct 1
222 23172806 Apoptosis induced by para-phenylenediamine involves formation of ROS and activation of p38 and JNK in chang liver cells. 2014 Sep 2
223 24019108 N-acetyl-L-cysteine enhances fisetin-induced cytotoxicity via induction of ROS-independent apoptosis in human colonic cancer cells. 2014 Feb 2
224 24213635 Leptin promotes the proliferation and migration of human breast cancer through the extracellular-signal regulated kinase pathway. 2014 Jan 2
225 24216289 Role of isothiocyanate conjugate of pterostilbene on the inhibition of MCF-7 cell proliferation and tumor growth in Ehrlich ascitic cell induced tumor bearing mice. 2014 Jan 15 1
226 24270523 Extracellular signal‑regulated kinase inhibition is required for methanol extract of Smilax china L.‑induced apoptosis through death receptor 5 in human oral mucoepidermoid carcinoma cells. 2014 Feb 1
227 24277696 Thrombin-induced CCAAT/enhancer-binding protein β activation and IL-8/CXCL8 expression via MEKK1, ERK, and p90 ribosomal S6 kinase 1 in lung epithelial cells. 2014 Jan 1 1
228 24348851 Downregulation of ERK signaling impairs U2OS osteosarcoma cell migration in collagen matrix by suppressing MMP9 production. 2014 Jan 2
229 24357020 Nardostachys chinensis induces the differentiation of human promyelocytic leukemic cells through the activation of the protein kinase C-dependent extracellular signal-regulated kinase signaling pathway. 2014 Mar 1
230 24385109 High-density lipoprotein induces cyclooxygenase-2 expression and prostaglandin I-2 release in endothelial cells through sphingosine kinase-2. 2014 Apr 1
231 24390819 The activation of P2Y2 receptors increases MCF-7 breast cancer cells migration through the MEK-ERK1/2 signalling pathway. 2014 Jun 1
232 24394624 Inhibition of hedgehog signaling by GANT58 induces apoptosis and shows synergistic antitumor activity with AKT inhibitor in acute T cell leukemia cells. 2014 Jun 1
233 24416349 The combination of RAD001 and MK-2206 exerts synergistic cytotoxic effects against PTEN mutant gastric cancer cells: involvement of MAPK-dependent autophagic, but not apoptotic cell death pathway. 2014 1
234 24424889 MHY-449, a novel dihydrobenzofuro[4,5-b][1,8] naphthyridin-6-one derivative, induces apoptotic cell death through modulation of Akt/FoxO1 and ERK signaling in PC3 human prostate cancer cells. 2014 Mar 2
235 24482702 ERK/CANP rapid signaling mediates 17β-estradiol-induced proliferation of human breast cancer cell line MCF-7 cells. 2014 1
236 24508476 Nitidine chloride induces apoptosis and inhibits tumor cell proliferation via suppressing ERK signaling pathway in renal cancer. 2014 Apr 1
237 24525463 Downregulation of Rad51 participates in OTA-induced DNA double-strand breaks in GES-1 cells in vitro. 2014 Apr 21 1
238 24596063 Loss of HSulf-1 expression enhances tumorigenicity by inhibiting Bim expression in ovarian cancer. 2014 Oct 15 1
239 24606459 Effect of TLR4 and B7-H1 on immune escape of urothelial bladder cancer and its clinical significance. 2014 1
240 24647664 Quercetin induces apoptosis by inhibiting MAPKs and TRPM7 channels in AGS cells. 2014 Jun 1
241 24700312 Paeoniflorin upregulates β-defensin-2 expression in human bronchial epithelial cell through the p38 MAPK, ERK, and NF-κB signaling pathways. 2014 Oct 1
242 24705173 Induction of autophagy by Tongxinluo through the MEK/ERK pathway protects human cardiac microvascular endothelial cells from hypoxia/reoxygenation injury. 2014 Aug 1
243 24833468 Connexin43 siRNA promotes HUVEC proliferation and inhibits apoptosis induced by ox-LDL: an involvement of ERK signaling pathway. 2014 Sep 1
244 24849420 MAPK signaling mediates low shear stress-induced oxidative damage in human umbilical vein endothelial cells in vitro. 2014 May 1
245 24857917 The cytoprotective effect of sulfuretin against tert-butyl hydroperoxide-induced hepatotoxicity through Nrf2/ARE and JNK/ERK MAPK-mediated heme oxygenase-1 expression. 2014 May 19 1
246 24955924 Collagen nanofibers facilitated presynaptic maturation in differentiated neurons from spinal-cord-derived neural stem cells through MAPK/ERK1/2-Synapsin I signaling pathway. 2014 Jul 14 1
247 24994563 Mechanistic aspects of lauryl gallate-induced differentiation and apoptosis in human acute myeloid leukemia cells. 2014 Sep 3
248 25093489 Exogenous IGFBP-2 promotes proliferation, invasion, and chemoresistance to temozolomide in glioma cells via the integrin β1-ERK pathway. 2014 Sep 23 1
249 25124623 Insulin promotes proliferation and migration of breast cancer cells through the extracellular regulated kinase pathway. 2014 2
250 25136261 Bone morphogenetic protein-9 induces PDLSCs osteogenic differentiation through the ERK and p38 signal pathways. 2014 1